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Philippe Chavrier

Philippe Chavrier

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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
25530
World Ranking
4717
National Ranking
127

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Philippe Chavrier is affiliated with the Institute Curie in France and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research predominantly focuses on cell biology, molecular biology, immunology and allergy, oncology, and cancer research.

The scientist's work covers various main topics including cellular mechanics and interactions, cell adhesion molecules research, protease and inhibitor mechanisms, cellular transport and secretion, peptidase inhibition and analysis, 3D printing in biomedical research, and Hippo pathway signaling and YAP/TAZ.

Frequent co-authors collaborating with Philippe Chavrier include:

  • Anne-Sophie Macé
  • Elisabetta Marangoni
  • Carine Rossé
  • Pedro Monteiro
  • David Remy

Their publications appear mostly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Cell Biology
  • Advanced Science
  • Cell
  • Nature Cell Biology

Recent notable papers include:

  • Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion, 2021, Cell
  • Protrudin-mediated ER-endosome contact sites promote MT1-MMP exocytosis and cell invasion, 2020, The Journal of Cell Biology
  • Intersection of TKS5 and FGD1/CDC42 signaling cascades directs the formation of invadopodia, 2020, The Journal of Cell Biology
  • Tissue remodeling by invadosomes, 2021, Faculty Reviews
  • Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance, 2021, Oncogene

Philippe Chavrier has been recognized as a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • ARF proteins: roles in membrane traffic and beyond.

    Crislyn D'Souza-Schorey;Philippe Chavrier

  • Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments.

    Philippe Chavrier;Robert G. Parton;Hans Peter Hauri;Kai Simons

  • rab5 controls early endosome fusion in vitro.

    Jean-Pierre Gorvel;Philippe Chavrier;Marino Zerial;Jean Gruenberg

  • Collective migration of an epithelial monolayer in response to a model wound

    M. Poujade;E. Grasland-Mongrain;A. Hertzog;J. Jouanneau

  • ARF6-regulated shedding of tumor cell-derived plasma membrane microvesicles.

    Vandhana Muralidharan-Chari;James Clancy;Carolyn Plou;Maryse Romao

  • Force mapping in epithelial cell migration

    Olivia Du Roure;Alexandre Saez;Axel Buguin;Robert Hamilton Austin

  • The role of ARF and Rab GTPases in membrane transport.

    Philippe Chavrier;Bruno Goud

  • Protein interaction mapping: A Drosophila case study

    Etienne Formstecher;Sandra Aresta;Vincent Collura;Alexandre Hamburger

  • Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse.

    David G. Wilkinson;Sangita Bhatt;Philippe Chavrier;Rodrigo Bravo

  • Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia.

    Renaud Poincloux;Floria Lizárraga;Philippe Chavrier

  • Hypervariable C-terminal domain of rab proteins acts as a targeting signal.

    Philippe Chavrier;Jean-Pierre Gorvel;Ernst Stelzer;Kai Simons

  • A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells.

    P. Chavrier;M. Zerial;P. Lemaire;J. Almendral

  • Both Epstein-Barr virus (EBV)-encoded trans-acting factors, EB1 and EB2, are required to activate transcription from an EBV early promoter

    A Chevallier-Greco;E Manet;P Chavrier;C Mosnier

  • Function of Rho family proteins in actin dynamics during phagocytosis and engulfment.

    Giovanna Chimini;Philippe Chavrier

  • The Rab7 GTPase resides on a vesicular compartment connected to lysosomes

    Stéphane Méresse;Jean-Pierre Gorvel;Philippe Chavrier

  • Contractility of the cell rear drives invasion of breast tumor cells in 3D Matrigel

    Renaud Poincloux;Olivier Collin;Floria Lizárraga;Maryse Romao

  • The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA

    Mika Sakurai-Yageta;Mika Sakurai-Yageta;Chiara Recchi;Chiara Recchi;Gaëlle Le Dez;Gaëlle Le Dez;Jean Baptiste Sibarita;Jean Baptiste Sibarita

  • EFA6, a sec7 domain-containing exchange factor for ARF6, coordinates membrane recycling and actin cytoskeleton organization

    Michel Franco;Peter J. Peters;Joëlle Boretto;Elly van Donselaar

  • Fc receptor‐mediated phagocytosis requires CDC42 and Rac1

    Philippe Massol;Philippe Montcourrier;Jean‐Claude Guillemot;Philippe Chavrier

  • Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis

    Cameron C. Scott;Wendy Dobson;Roberto J. Botelho;Natasha Coady-Osberg

Frequent Co-Authors

Graça Raposo
Graça Raposo Institut Curie
Jean-Pierre Gorvel
Jean-Pierre Gorvel Aix-Marseille University
Marino Zerial
Marino Zerial Max Planck Society
Anne Vincent-Salomon
Anne Vincent-Salomon Institute Curie
Uwe Schlattner
Uwe Schlattner Grenoble Alpes University
Crislyn D'Souza-Schorey
Crislyn D'Souza-Schorey University of Notre Dame
Anne Houdusse
Anne Houdusse Université Paris Cité
Kai Simons
Kai Simons Lipotype
Olivier Delattre
Olivier Delattre PSL University

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