What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Neuron
His primary scientific interests are in Cell biology, Biochemistry, Neuroscience, Synaptic plasticity and Cerebellar cortex.
His study in Cell biology is interdisciplinary in nature, drawing from both NMDA receptor, Gene expression and Cellular differentiation.
His biological study spans a wide range of topics, including Myocyte and Immunohistochemistry.
Hiroyuki Sakagami combines subjects such as Long-term potentiation, Knockout mouse and Protein kinase A with his study of Synaptic plasticity.
As part of the same scientific family, Hiroyuki Sakagami usually focuses on Long-term potentiation, concentrating on Fatty acid-binding protein and intersecting with Endocrinology and Internal medicine.
His work in Cerebellar cortex addresses subjects such as Molecular biology, which are connected to disciplines such as Hippocampus, Dorsal cochlear nucleus, GABAergic and Genetically modified mouse.
His most cited work include:
- Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2. (313 citations)
- Rac1 is required for the formation of three germ layers during gastrulation. (294 citations)
- Localization of mRNAs of voltage-dependent Ca2+-channels: four subtypes of α1- and β-subunits in developing and mature rat brain (170 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Cell biology, Molecular biology, Hippocampal formation, Endocrinology and Internal medicine.
The concepts of his Cell biology study are interwoven with issues in Biochemistry and Postsynaptic density.
His Molecular biology research is multidisciplinary, incorporating elements of In situ hybridization, Complementary DNA, Messenger RNA, Gene and Gene isoform.
In his work, Cerebellar cortex is strongly intertwined with Olfactory bulb, which is a subfield of Hippocampal formation.
His work carried out in the field of Endocrinology brings together such families of science as Angiogenesis and Immunology.
His Ca2+/calmodulin-dependent protein kinase study combines topics from a wide range of disciplines, such as Cerebellum, Long-term potentiation, MAP2K7 and Mitogen-activated protein kinase kinase.
He most often published in these fields:
- Cell biology (52.79%)
- Molecular biology (25.38%)
- Hippocampal formation (16.24%)
What were the highlights of his more recent work (between 2014-2021)?
- Cell biology (52.79%)
- ADP ribosylation factor (12.69%)
- Internal medicine (15.23%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Cell biology, ADP ribosylation factor, Internal medicine, Endocrinology and Neuroscience.
In his research, Autosomal dominant trait is intimately related to Mutant, which falls under the overarching field of Cell biology.
Hiroyuki Sakagami has researched ADP ribosylation factor in several fields, including Immunolabeling, Guanine nucleotide exchange factor, GTPase, Actin remodeling and Subcellular localization.
His Internal medicine research focuses on subjects like Ca2+/calmodulin-dependent protein kinase, which are linked to Hippocampus, Hippocampal formation, Dentate gyrus and Sigma-1 receptor.
His work on Kidney as part of general Endocrinology research is frequently linked to Bilateral Renal Agenesis, Polyhydramnios, Pulmonary hypoplasia and Amnion, thereby connecting diverse disciplines of science.
Hiroyuki Sakagami interconnects NMDA receptor, Knockout mouse and Postsynaptic potential in the investigation of issues within Neuroscience.
Between 2014 and 2021, his most popular works were:
- CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility (50 citations)
- Stimulation of Sigma-1 Receptor Ameliorates Depressive-like Behaviors in CaMKIV Null Mice (31 citations)
- ADP Ribosylation Factor 6 Regulates Neuronal Migration in the Developing Cerebral Cortex through FIP3/Arfophilin-1-dependent Endosomal Trafficking of N-cadherin (26 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Neuron
Hiroyuki Sakagami mainly investigates Cell biology, Internal medicine, Endocrinology, Neuroscience and Long-term potentiation.
He regularly ties together related areas like Myelin in his Cell biology studies.
The various areas that Hiroyuki Sakagami examines in his Internal medicine study include Immunology and Agenesis.
His Kidney and Stimulation study, which is part of a larger body of work in Endocrinology, is frequently linked to Pulmonary hypoplasia, Amnion and Amniotic fluid, bridging the gap between disciplines.
His studies deal with areas such as NMDA receptor, Receptor, Postsynaptic potential, Gene knockdown and Imprinting as well as Neuroscience.
In his research on the topic of Long-term potentiation, Hippocampus, Hippocampal formation, Dentate gyrus and Protein kinase B is strongly related with Ca2+/calmodulin-dependent protein kinase.
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