World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
80
Citations
20216
World Ranking
1634
National Ranking
798

Biology and Biochemistry

D-Index
81
Citations
20485
World Ranking
3948
National Ranking
1948

Overview

Wen Cheng Xiong is affiliated with Case Western Reserve University in the United States, with a research focus spanning medicine, biochemistry, genetics, molecular biology, and neuroscience. Their work covers a substantial body of publications with notable contributions in molecular biology and cellular and molecular neuroscience.

The scientist's research topics include:

  • Neuroscience and Neuropharmacology Research
  • Cellular transport and secretion
  • Neurogenesis and neuroplasticity mechanisms
  • Tryptophan and brain disorders
  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Genetics and Neurodevelopmental Disorders

Major recent papers authored by Wen Cheng Xiong include:

  • "The ATP Level in the Medial Prefrontal Cortex Regulates Depressive-like Behavior via the Medial Prefrontal Cortex-Lateral Habenula Pathway" (2022), published in Biological Psychiatry
  • "Lactate Metabolism, Signaling, and Function in Brain Development, Synaptic Plasticity, Angiogenesis, and Neurodegenerative Diseases" (2023), published in International Journal of Molecular Sciences
  • "A Role of Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) in Astrocytic Aβ Clearance" (2020), published in Journal of Neuroscience
  • "Neddylation stabilizes Nav1.1 to maintain interneuron excitability and prevent seizures in murine epilepsy models" (2021), published in Journal of Clinical Investigation
  • "Coupling of terminal differentiation deficit with neurodegenerative pathology in Vps35-deficient pyramidal neurons" (2020), published in Cell Death and Differentiation

Frequent co-authors of Wen Cheng Xiong include:

  • Lin Mei
  • Daehoon Lee
  • Xiao Ren
  • Jin-Xiu Pan
  • Hongsheng Wang

The scientist frequently publishes in several prominent venues, with the highest number of publications appearing in the Journal of Neuroscience. Other venues include:

  • Neuron
  • Biological Psychiatry
  • International Journal of Molecular Sciences
  • Nature Communications

Wen Cheng Xiong's work covers a range of scientific disciplines, and their main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

Subfields within these disciplines prominently featured in their publications are:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Physiology
  • Neurology
  • Cell Biology

Best Publications

  • Neuregulin 1 in neural development, synaptic plasticity and schizophrenia

    Lin Mei;Wen Cheng Xiong

  • Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.

    Kit Wong;Xiu Rong Ren;Yang Zhong Huang;Yi Xie

  • LRP4 serves as a coreceptor of agrin.

    Bin Zhang;Shiwen Luo;Qiang Wang;Tatsuo Suzuki

  • To build a synapse: Signaling pathways in neuromuscular junction assembly

    Haitao Wu;Wen C. Xiong;Lin Mei

  • Regulation of Neuregulin Signaling by PSD-95 Interacting with ErbB4 at CNS Synapses

    Yang Z. Huang;Yang Z. Huang;Yang Z. Huang;Sandra Won;Declan W. Ali;Qiang Wang;Qiang Wang;Qiang Wang

  • Autoantibodies to Lipoprotein-Related Protein 4 in Patients With Double-Seronegative Myasthenia Gravis

    Bin Zhang;John S. Tzartos;Maria Belimezi;Samia Ragheb

  • GADD34–PP1c recruited by Smad7 dephosphorylates TGFβ type I receptor

    Weibin Shi;Chuanxi Sun;Bin He;Wencheng Xiong

  • Neuregulin 1 regulates pyramidal neuron activity via ErbB4 in parvalbumin-positive interneurons

    Lei Wen;Yi Sheng Lu;Xin Hong Zhu;Xiao Ming Li

  • Neuregulin-1 enhances depolarization-induced GABA release.

    Ran Sook Woo;Xiao Ming Li;Xiao Ming Li;Yanmei Tao;Ezekiel Carpenter-Hyland

  • Cell-type based analysis of microRNA profiles in the mouse brain

    Miao He;Miao He;Yu Liu;Xiaowo Wang;Michael Q. Zhang;Michael Q. Zhang

  • Neuromuscular Junction Formation, Aging, and Disorders.

    Lei Li;Wen-Cheng Xiong;Wen-Cheng Xiong;Lin Mei;Lin Mei

  • Identification of a Novel Cortactin SH3 Domain-Binding Protein and Its Localization to Growth Cones of Cultured Neurons

    Yunrui Du;Scott A. Weed;Wen Cheng Xiong;Trudy D. Marshall

  • VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease.

    Fu Lei Tang;Joanna R. Erion;Yun Tian;Wei Liu

  • Focal adhesion kinase in netrin-1 signaling

    Xiu Rong Ren;Guo Li Ming;Yi Xie;Yan Hong

  • Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1

    Zhen G Luo;Qiang Wang;Qiang Wang;Jian Z Zhou;Jianbo Wang

  • VPS35 haploinsufficiency increases Alzheimer’s disease neuropathology

    Lei Wen;Fu Lei Tang;Yan Hong;Shi Wen Luo

  • YAP promotes osteogenesis and suppresses adipogenic differentiation by regulating β-catenin signaling.

    Jin Xiu Pan;Jin Xiu Pan;Lei Xiong;Lei Xiong;Kai Zhao;Kai Zhao;Peng Zeng;Peng Zeng

  • VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function.

    Fu Lei Tang;Fu Lei Tang;Wei Liu;Wei Liu;Jin Xia Hu;Joanna Ruth Erion

  • ErbB4 in parvalbumin-positive interneurons is critical for neuregulin 1 regulation of long-term potentiation

    Yong Jun Chen;Meng Zhang;Dong Min Yin;Lei Wen

  • Neuregulin 1 promotes excitatory synapse development and function in GABAergic interneurons.

    Annie K. Ting;Yongjun Chen;Lei Wen;Dong Min Yin

Frequent Co-Authors

Lin Mei
Lin Mei Case Western Reserve University
Wei Liu
Wei Liu Huazhong University of Science and Technology
Yu-Qiang Ding
Yu-Qiang Ding Fudan University
Jay M. McDonald
Jay M. McDonald University of Alabama at Birmingham
Yi Rao
Yi Rao Peking University
Bai Lu
Bai Lu Tsinghua University
Craig Montell
Craig Montell University of California, Santa Barbara
Susan L. Ackerman
Susan L. Ackerman University of California, San Diego
Shihua Li
Shihua Li Southeast University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Wen Cheng Xiong

Trending Scientists

Recently Published Articles