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Biology and Biochemistry

D-Index
64
Citations
17137
World Ranking
9545
National Ranking
4213

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1980 - Fellow of Alfred P. Sloan Foundation

Overview

Steven J. Burden is affiliated with New York University in the United States. Their research spans several domains within medicine and biochemistry, genetics, and molecular biology, with a strong focus on neurological and muscular disorders.

The main fields of study in which Steven J. Burden has contributed include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields of particular focus are:

  • Neurology
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging
  • Genetics
  • Cell Biology

Research topics frequently addressed in their work cover:

  • Myasthenia Gravis and Thymoma
  • Monoclonal and Polyclonal Antibodies Research
  • Peripheral Neuropathies and Disorders
  • Advanced biosensing and bioanalysis techniques
  • Neurogenetic and Muscular Disorders Research
  • RNA Research and Splicing
  • Cellular transport and secretion

Among their recent publications are the following papers:

  • Mechanism of disease and therapeutic rescue of Dok7 congenital myasthenia, 2021, Nature
  • Affinity maturation is required for pathogenic monovalent IgG4 autoantibody development in myasthenia gravis, 2020, The Journal of Experimental Medicine
  • The Platform Vector Gene Therapies Project: Increasing the Efficiency of Adeno-Associated Virus Gene Therapy Clinical Trial Startup, 2020, Human Gene Therapy
  • Activation of Muscle-Specific Kinase (MuSK) Reduces Neuromuscular Defects in the Delta7 Mouse Model of Spinal Muscular Atrophy (SMA), 2021, International Journal of Molecular Sciences
  • ARGX-119 is an agonist antibody for human MuSK that reverses disease relapse in a mouse model of congenital myasthenic syndrome, 2024, Science Translational Medicine

Steven J. Burden has collaborated frequently with a number of co-authors including:

  • Julien Oury
  • Casey Vieni
  • Rachel L. Redler
  • Damian C. Ekiert
  • Kevin C. O'Connor

Their work has appeared in multiple publication venues, notable among them are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • The Journal of Experimental Medicine
  • Human Gene Therapy
  • International Journal of Molecular Sciences

Steven J. Burden has been recognized with the following awards:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2013
  • Fellow of Alfred P. Sloan Foundation, 1980

Best Publications

  • FoxO3 controls autophagy in skeletal muscle in vivo.

    Cristina Mammucari;Giulia Milan;Vanina Romanello;Eva Masiero

  • The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

    Thomas M DeChiara;David C Bowen;David M Valenzuela;Mary V Simmons

  • Agrin Acts via a MuSK Receptor Complex

    David J Glass;David C Bowen;Trevor N Stitt;Czeslaw Radziejewski

  • Lrp4 Is a Receptor for Agrin and Forms a Complex with MuSK

    Natalie Kim;Amy L. Stiegler;Thomas O. Cameron;Peter T. Hallock

  • Neuregulins and Their Receptors: A Versatile Signaling Module in Organogenesis and Oncogenesis

    Steve Burden;Yosef Yarden

  • Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation

    Xia Yang;Silvia Arber;Christopher William;Li Li

  • Receptor tyrosine kinase specific for the skeletal muscle lineage: Expression in embryonic muscle, at the neuromuscular junction, and after injury

    David M. Valenzuela;Trevor N. Stitt;Peter S. DiStefano;Eduardo Rojas

  • Acetylcholine receptors in regenerating muscle accumulate at original synaptic sites in the absence of the nerve.

    S J Burden;P B Sargent;U J McMahan

  • DNA topoisomerase IIβ and neural development

    Xia Yang;Wei Li;Elizabeth D. Prescott;Steven J. Burden

  • Neuregulins are concentrated at nerve-muscle synapses and activate ACh–receptor gene expression

    Sangmee Ahn Jo;Xuejun Zhu;Xuejun Zhu;Mark A. Marchionni;Steven J. Burden

  • Increased mitochondrial mass in mitochondrial myopathy mice.

    Anna Wredenberg;Rolf Wibom;Hans Wilhelmsson;Caroline Graff

  • MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4

    Maartje G. Huijbers;Wei Zhang;Rinse Klooster;Erik H. Niks

  • A dystroglycan mutation associated with limb-girdle muscular dystrophy.

    Yuji Hara;Burcu Balci-Hayta;Takako Yoshida-Moriguchi;Motoi Kanagawa

  • The formation of neuromuscular synapses

    Steven J. Burden

  • Crosslinking of proteins in acetylcholine receptor-rich membranes: Association between the β-subunit and the 43 kd subsynaptic protein

    S.J. Burden;R.L. Depalma;G.S. Gottesman

  • Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses

    Norihiro Yumoto;Natalie Kim;Steven J. Burden

  • Neuregulins and their receptors.

    Kermit L Carraway;Steven J Burden

  • Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle

    Xiaoxia Wang;Chris Blagden;Jihua Fan;Scott J. Nowak

  • Neuregulin receptors, erbB3 and erbB4, are localized at neuromuscular synapses.

    Xuejun Zhu;C. Lai;S. Thomas;S. J. Burden

  • MuSK controls where motor axons grow and form synapses

    Natalie Kim;Steven J Burden

Frequent Co-Authors

Stevan R. Hubbard
Stevan R. Hubbard New York University
Michael L. Dustin
Michael L. Dustin University of Oxford
Thomas A. Neubert
Thomas A. Neubert New York University
David J. Glass
David J. Glass Regeneron (United States)
Antonella Viola
Antonella Viola University of Padua
Silvia Arber
Silvia Arber University of Basel
Robert C. Froemke
Robert C. Froemke New York University
George Z. Mentis
George Z. Mentis Columbia University
Stefan Kunz
Stefan Kunz University of Lausanne
Silvère M. van der Maarel
Silvère M. van der Maarel Leiden University Medical Center

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