World's Best Scientists 2026 revealed!
Jean-Pierre Changeux

Jean-Pierre Changeux

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Best Scientists
2025
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Neuroscience
France
2026

D-Index & Metrics

Best Scientists

D-Index
167
Citations
109069
World Ranking
976
National Ranking
20

Neuroscience

D-Index
169
Citations
110068
World Ranking
78
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Neuroscience in France Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Neuroscience in France Leader Award
  • 2023 - Research.com Neuroscience in France Leader Award
  • 2022 - Research.com Neuroscience in France Leader Award
  • 2010 - Robert J. and Claire Pasarow Foundation Medical Research Award
  • 2007 - NAS Award in the Neurosciences, U.S. National Academy of Sciences For the pioneering discovery that fast-acting neurotransmitters mediate their effects through allosteric regulation of the neurotransmitter protein.
  • 2003 - Member of the European Academy of Sciences
  • 2002 - Karl Spencer Lashley Award, The American Philosophical Society In recognition of his pioneering, comprehensive studies into the fundamental molecular mechanisms underlying interneuronal communication and their role in network formation, learning, and reward
  • 2001 - International Balzan Prize
  • 2000 - Member of the National Academy of Medicine (NAM)
  • 1994 - Fellow of the American Academy of Arts and Sciences
  • 1992 - CNRS Gold Medal, French National Centre for Scientific Research Neurobiology
  • 1988 - Member of Academia Europaea
  • 1983 - Member of the National Academy of Sciences
  • 1982 - Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences for their work on fundamental structures of genetic material and of the nervous system.
  • 1978 - Canada Gairdner International Award
  • 1974 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Physiology and Pharmacology/Toxicology
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Jean-Pierre Changeux is affiliated with the Institut Pasteur in France and has a significant body of work primarily in the fields of Biochemistry, Genetics and Molecular Biology, with a strong focus on Neuroscience. Their research spans molecular biology and cognitive neuroscience, including cellular and molecular neuroscience aspects.

Their recent publications include the following papers:

  • The natural axis of transmitter receptor distribution in the human cerebral cortex (2021), Proceedings of the National Academy of Sciences
  • A Connectomic Hypothesis for the Hominization of the Brain (2020), Cerebral Cortex
  • Differential mechanisms underlie trace and delay conditioning in Drosophila (2022), Nature
  • Attenuation of clinical and immunological outcomes during SARS-CoV-2 infection by ivermectin (2021), EMBO Molecular Medicine
  • Do Nicotinic Receptors Modulate High-Order Cognitive Processing? (2020), Trends in Neurosciences

Frequent co-authors collaborating with Jean-Pierre Changeux include:

  • Marco Cecchini
  • Claus C. Hilgetag
  • Katrin Amunts
  • Pierre-Jean Corringer
  • Adrien Henri Cerdan

Their works are often published in venues such as:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Comptes Rendus Biologies
  • Zenodo (CERN European Organization for Nuclear Research)

Main topics of their research include:

  • Nicotinic Acetylcholine Receptors Study
  • Receptor Mechanisms and Signaling
  • Neural dynamics and brain function
  • Neuroscience and Neuropharmacology Research
  • Functional Brain Connectivity Studies
  • EEG and Brain-Computer Interfaces
  • Ion channel regulation and function

Jean-Pierre Changeux has been recognized with multiple awards including:

  • Robert J. and Claire Pasarow Foundation Medical Research Award (2010)
  • NAS Award in the Neurosciences, U.S. National Academy of Sciences (2007) for pioneering discoveries in neurotransmitter protein regulation
  • Member of the European Academy of Sciences (2003)
  • Karl Spencer Lashley Award, The American Philosophical Society (2002) for studies on interneuronal communication
  • International Balzan Prize (2001)
  • Member of the National Academy of Medicine (2000)
  • Fellow of the American Academy of Arts and Sciences (1994)
  • CNRS Gold Medal, French National Centre for Scientific Research (1992) in Neurobiology
  • Member of Academia Europaea (1988)
  • Member of the National Academy of Sciences (1983)
  • Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences (1982)
  • Canada Gairdner International Award (1978)
  • German National Academy of Sciences Leopoldina (1974)
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • On the Nature of Allosteric Transitions: A Plausible Model

    Jacques Monod;Jeffries Wyman;Jean-Pierre Changeux

  • Allosteric Proteins and Cellular Control Systems

    Jacques Monod;Jean-Pierre Changeux;François Jacob

  • Experimental and Theoretical Approaches to Conscious Processing

    Stanislas Dehaene;Jean-Pierre Changeux;Jean-Pierre Changeux

  • Conscious, preconscious, and subliminal processing: a testable taxonomy.

    Stanislas Dehaene;Jean Pierre Changeux;Jean Pierre Changeux;Lionel Naccache;Jérôme Sackur

  • A Neuronal Model of a Global Workspace in Effortful Cognitive Tasks

    Stanislas Dehaene;Michel Kerszberg;Jean-Pierre Changeux

  • Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks.

    Jean-Pierre Changeux;Antoine Danchin

  • Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine

    Marina R. Picciotto;Marina R. Picciotto;Michele Zoli;Roberto Rimondini;Clément Léna

  • Nicotinic receptors at the amino acid level.

    Corringer Pj;Le Novère N;Changeux Jp

  • A neuronal network model linking subjective reports and objective physiological data during conscious perception

    Stanislas Dehaene;Claire Sergent;Jean-Pierre Changeux

  • Neuronal man : the biology of mind

    Jean-Pierre Changeux

  • Development of elementary numerical abilities: A neuronal model

    Stanislas Dehaene;Jean-Pierre Changeux

  • Conscious Processing and the Global Neuronal Workspace Hypothesis.

    George A. Mashour;Pieter Roelfsema;Pieter Roelfsema;Jean Pierre Changeux;Jean Pierre Changeux;Jean Pierre Changeux;Stanislas Dehaene;Stanislas Dehaene

  • Acetylcholine receptor: an allosteric protein

    Jean-Pierre Changeux;Jean-Pierre Changeux;Anne Devillers-Thiéry;Phillippe Chemouilli

  • Allosteric mechanisms of signal transduction.

    Jean-Pierre Changeux;Jean-Pierre Changeux;Stuart J. Edelstein;Stuart J. Edelstein

  • Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

    Antoine Taly;Pierre-Jean Corringer;Denis Guedin;Pierre Lestage

  • Use of a Snake Venom Toxin to Characterize the Cholinergic Receptor Protein

    Jean-Pierre Changeux;Michiki Kasai;Chen-Yuan Lee

  • Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain.

    Marina R. Picciotto;Michele Zoli;Clement Léna;Alain Bessis

  • International Union of Pharmacology. XX. Current Status of the Nomenclature for Nicotinic Acetylcholine Receptors and Their Subunits

    R. J. Lukas;J.-P. Changeux;N. Le Novere;E. X. Albuquerque

  • Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors.

    U. Maskos;B. E. Molles;S. Pons;M. Besson;M. Besson

  • Molecular and Physiological Diversity of Nicotinic Acetylcholine Receptors in the Midbrain Dopaminergic Nuclei

    Ruby Klink;Alban de Kerchove d'Exaerde;Michele Zoli;Michele Zoli;Jean-Pierre Changeux

Frequent Co-Authors

Marina R. Picciotto
Marina R. Picciotto Yale University
Stanislas Dehaene
Stanislas Dehaene Collège de France
Michele Zoli
Michele Zoli University of Modena and Reggio Emilia
Uwe Maskos
Uwe Maskos Institut Pasteur
Clément Léna
Clément Léna École Normale Supérieure
Nicolas Le Novère
Nicolas Le Novère Babraham Institute
Christophe Mulle
Christophe Mulle University of Bordeaux
Daniel Bertrand
Daniel Bertrand University of Geneva
Thierry Heidmann
Thierry Heidmann Institut Gustave Roussy
Sonia Bertrand
Sonia Bertrand University of Geneva

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