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Thierry Heidmann

Thierry Heidmann

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Genetics
France
2024
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Genetics and Molecular Biology
France
2024

D-Index & Metrics

Genetics

D-Index
75
Citations
20219
World Ranking
1903
National Ranking
84

Research.com Recognitions

  • 2024 - Research.com Genetics in France Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in France Leader Award

Overview

Thierry Heidmann is a researcher affiliated with the Institut Gustave Roussy in France. Their work is primarily situated within the broad field of Biochemistry, Genetics and Molecular Biology, with specific focus areas including Molecular Biology, Genetics, Plant Science, Virology, and Epidemiology.

The scientist's research covers a range of topics reflecting a strong intersection of molecular mechanisms and disease-related studies. These main topics include:

  • RNA modifications and cancer
  • Chromosomal and Genetic Variations
  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation
  • HIV Research and Treatment
  • Virology and Viral Diseases
  • Virus-based gene therapy research

Thierry Heidmann's recent scholarly output includes several publications spanning from 2021 to 2024. These papers demonstrate engagement with molecular oncology, virology, and innovative assay development approaches. Notable recent papers include:

  • "Therapeutic potential of the human endogenous retroviral envelope protein HEMO: a pan-cancer analysis" (2021) published in Molecular Oncology
  • "A recombinant measles virus vaccine strongly reduces SHIV viremia and virus reservoir establishment in macaques" (2021) published in npj Vaccines
  • "Sodium-dependent phosphate transporter PiT1/SLC20A1 as the receptor for the endogenous retroviral envelope syncytin-B involved in mouse placenta formation" (2024) published in Journal of Virology
  • "Cell-Int: a cell-cell interaction assay to identify native membrane protein interactions" (2024) published in Life Science Alliance
  • "Targeting the paralog protein for degradation accounts for the opposite roles of NRBP1 and NRBP2 in regulating LINE1 retrotransposition" (2024) published in bioRxiv (Cold Spring Harbor Laboratory)

Their co-researchers often include Gérard Pierron, Guillaume Mousseau, Anne Dupressoír, Agathe Bacquin, and Shaobo Cong, each collaborating on at least two publications. The diversity of frequent publication venues reflects a multidisciplinary approach with contributions to Molecular Oncology, npj Vaccines, Life Science Alliance, Journal of Virology, and bioRxiv.

Best Publications

  • LINE-mediated retrotransposition of marked Alu sequences

    Marie Dewannieux;Cécile Esnault;Thierry Heidmann

  • Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

    Daniel B. Stetson;Joan S. Ko;Thierry Heidmann;Ruslan Medzhitov

  • Human LINE retrotransposons generate processed pseudogenes.

    Cécile Esnault;Joël Maestre;Thierry Heidmann

  • Structural and functional properties of the acetylcholine receptor protein in its purified and membrane-bound states.

    Thierry Heidmann;Jean-Pierre Changeux

  • APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses.

    Cécile Esnault;Odile Heidmann;Frédéric Delebecque;Marie Dewannieux

  • Syncytin-A and syncytin-B, two fusogenic placenta-specific murine envelope genes of retroviral origin conserved in Muridae.

    Anne Dupressoir;Geoffroy Marceau;Cécile Vernochet;Laurence Bénit

  • Identification of an infectious progenitor for the multiple-copy HERV-K human endogenous retroelements

    Marie Dewannieux;Francis Harper;Aurélien Richaud;Claire Letzelter

  • Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene

    Anne Dupressoir;Cécile Vernochet;Olivia Bawa;Francis Harper

  • Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine.

    Jerome Giraudat;Michael Dennis;Thierry Heidmann;Jui-Yoa Chang

  • Paleovirology of ‘syncytins’, retroviral env genes exapted for a role in placentation

    Christian Lavialle;Guillaume Cornelis;Guillaume Cornelis;Anne Dupressoir;Anne Dupressoir;Cécile Esnault;Cécile Esnault

  • From ancestral infectious retroviruses to bona fide cellular genes: Role of the captured syncytins in placentation

    A. Dupressoir;C. Lavialle;C. Lavialle;T. Heidmann;T. Heidmann

  • Placental syncytins: Genetic disjunction between the fusogenic and immunosuppressive activity of retroviral envelope proteins

    Marianne Mangeney;Martial Renard;Géraldine Schlecht-Louf;Isabelle Bouallaga

  • Multiple sites of action for noncompetitive blockers on acetylcholine receptor rich membrane fragments from Torpedo marmorata

    Thierry Heidmann;Robert E. Oswald;Jean Pierre Changeux

  • High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition

    Ya-Lin Chiu;H. Ewa Witkowska;Steven C. Hall;Mario Santiago

  • Taming of transposable elements by homology-dependent gene silencing

    Silke Jensen;Marie-Pierre Gassama;Thierry Heidmann

  • Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: [3H]chlorpromazine labels homologous residues in the .beta. and .delta. chains

    Jerome Giraudat;Michael Dennis;Thierry Heidmann;Pierre Yves Haumont

  • A placenta-specific receptor for the fusogenic, endogenous retrovirus-derived, human syncytin-2.

    Cécile Esnault;Stéphane Priet;David Ribet;Cécile Vernochet

  • Cloning of a new murine endogenous retrovirus, MuERV-L, with strong similarity to the human HERV-L element and with a gag coding sequence closely related to the Fv1 restriction gene.

    L Bénit;N De Parseval;J F Casella;I Callebaut

  • A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast

    Anne Dupressoir;Cécile Vernochet;Francis Harper;Justine Guégan

  • Members of the SRY family regulate the human LINE retrotransposons

    Thierry Tchénio;Jean-François Casella;Thierry Heidmann

Frequent Co-Authors

Jean-Pierre Changeux
Jean-Pierre Changeux Institut Pasteur
Gérard Pierron
Gérard Pierron Centre national de la recherche scientifique, CNRS
André Sobel
André Sobel Grenoble Alpes University
Olivier Schwartz
Olivier Schwartz Université Paris Cité
Philippe Dessen
Philippe Dessen Institut Gustave Roussy
François Catzeflis
François Catzeflis University of Montpellier
Marc Lecuit
Marc Lecuit Institut Pasteur
Eviatar Nevo
Eviatar Nevo University of Haifa
Bud C. Tennant
Bud C. Tennant Cornell University
Gilles Thomas
Gilles Thomas Grenoble Alpes University

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