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Biology and Biochemistry

D-Index
70
Citations
23010
World Ranking
6892
National Ranking
218

Overview

Philippe Dessen is affiliated with the Institut Gustave Roussy in France and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their body of work spans several subfields, including molecular biology, oncology, cancer research, immunology, and hematology.

Research topics central to Dessen's work include:

  • Cancer Genomics and Diagnostics
  • RNA modifications and cancer
  • Neuroblastoma Research and Treatments
  • CAR-T cell therapy research
  • Epigenetics and DNA Methylation
  • Chronic Myeloid Leukemia Treatments
  • Muscle Physiology and Disorders

They have published papers in several scientific venues, notably including:

  • Cancers
  • UNC Libraries
  • Communications Biology
  • OncoImmunology
  • The EMBO Journal

Recent publications by Philippe Dessen showcase a focus on cancer biology and molecular mechanisms, with highlighted works such as:

  • "Hypoxia increases mutational load of breast cancer cells through frameshift mutations," 2020, OncoImmunology
  • "DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability," 2021, The EMBO Journal
  • "A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors," 2023, Communications Biology
  • "Dual role of EZH2 in megakaryocyte differentiation," 2021, Blood
  • "Adipose Tissue Properties in Tumor-Bearing Breasts," 2020, Frontiers in Oncology

Philippe Dessen's collaborations often include frequent coauthors such as Antonin Marchais, Birgit Geoerger, Jean-Yves Scoazec, Maria Eugénia Marques Da Costa, and Wan Ching Lim. These collaborative efforts underline a diverse network of research partnerships in related fields.

Best Publications

  • PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

    Muhammad Zaeem Noman;Giacomo Desantis;Bassam Janji;Meriem Hasmim

  • Mutation in TET2 in Myeloid Cancers

    François Delhommeau;Sabrina Dupont;Véronique Della Valle;Chloé James

  • Inhibition of macroautophagy triggers apoptosis.

    Patricia Boya;Rosa-Ana González-Polo;Noelia Casares;Jean-Luc Perfettini

  • Extent of N-terminal methionine excision from Escherichia coli proteins is governed by the side-chain length of the penultimate amino acid.

    P H Hirel;M J Schmitter;P Dessen;G Fayat

  • TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis

    Cyril Quivoron;Cyril Quivoron;Cyril Quivoron;Lucile Couronné;Lucile Couronné;Lucile Couronné;Véronique Della Valle;Véronique Della Valle;Véronique Della Valle;Cécile K. Lopez;Cécile K. Lopez;Cécile K. Lopez

  • Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia

    Jean-Marc Aury;Olivier Jaillon;Laurent Duret;Benjamin Noel

  • Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death?

    Céline Candé;Francesco Cecconi;Philippe Dessen;Guido Kroemer

  • A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

    Corine Bertolotto;Fabienne Lesueur;Sandy Giuliano;Thomas Strub

  • Gene Expression Profiling of Primary Cutaneous Melanoma and Clinical Outcome

    Véronique Winnepenninckx;Vladimir Lazar;Stefan Michiels;Philippe Dessen

  • Molecular Characterization of Breast Cancer with High-Resolution Oligonucleotide Comparative Genomic Hybridization Array

    Fabrice Andre;Bastien Job;Philippe Dessen;Philippe Dessen;Attila Tordai

  • Characterization of a large panel of patient-derived tumor xenografts representing the clinical heterogeneity of human colorectal cancer.

    Sylvia Julien;Ana Merino-Trigo;Ludovic Lacroix;Marc Pocard

  • miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death

    Lorenzo Galluzzi;Eugenia Morselli;Ilio Vitale;Oliver Kepp

  • Acquired initiating mutations in early hematopoietic cells of CLL patients

    Frederik Damm;Frederik Damm;Elena Mylonas;Elena Mylonas;Adrien Cosson;Adrien Cosson;Kenichi Yoshida

  • High expression of DNA repair pathways is associated with metastasis in melanoma patients.

    A Kauffmann;F Rosselli;V Lazar;V Winnepenninckx

  • Light-scattering studies showing the effect of initiation factors on the reversible dissociation of Escherichia coli ribosomes.

    M Grunberg-Manago;P Dessen;D Pantaloni;T Godefroy-Colburn

  • Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas.

    Stephanie Puget;Cathy Philippe;Dorine A. Bax;Bastien Job

  • Apoptosis regulation in tetraploid cancer cells

    Maria Castedo;Arnaud Coquelle;Sonia Vivet;Ilio Vitale

  • A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast

    Anne Dupressoir;Cécile Vernochet;Francis Harper;Justine Guégan

  • Atlas of Genetics and Cytogenetics in Oncology and Haematology in 2013

    Jean-Loup Huret;Mohammad Ahmad;Mélanie Arsaban;Alain Bernheim

  • Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia

    Celine Callens;Séverine Coulon;Séverine Coulon;Jerome Naudin;Isabelle Radford-Weiss;Isabelle Radford-Weiss

Frequent Co-Authors

Guido Kroemer
Guido Kroemer Université Paris Cité
Alain Bernheim
Alain Bernheim Institut Gustave Roussy
Stefan Michiels
Stefan Michiels University of Paris-Saclay
Alain Sarasin
Alain Sarasin Institut Gustave Roussy
Caroline Robert
Caroline Robert University of Paris-Saclay
Sylvain Blanquet
Sylvain Blanquet École Polytechnique
Nathalie Droin
Nathalie Droin Institut Gustave Roussy
Ilio Vitale
Ilio Vitale University of Rome Tor Vergata
William Vainchenker
William Vainchenker Institut Gustave Roussy
Lorenzo Galluzzi
Lorenzo Galluzzi Cornell University

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