Palle Serup focuses on Internal medicine, Cell biology, Endocrinology, Pancreas and Enteroendocrine cell. His Internal medicine research includes themes of NeuroD and Cellular differentiation. His study in Cell biology is interdisciplinary in nature, drawing from both Transcription factor and PAX6.
His research combines Frizzled and Endocrinology. His Pancreas research is multidisciplinary, incorporating perspectives in PAX4, Morphogenesis, Glucagon, Endocrine system and Pancreas morphogenesis. Palle Serup combines subjects such as Precursor cell, Endoderm and Notch signaling pathway with his study of Enteroendocrine cell.
His main research concerns Cell biology, Internal medicine, Endocrinology, Pancreas and Molecular biology. His work deals with themes such as Embryonic stem cell, Enteroendocrine cell and Cellular differentiation, which intersect with Cell biology. His Internal medicine research is multidisciplinary, incorporating elements of Regulation of gene expression and Stem cell.
His Endocrinology research incorporates elements of Receptor, Mesenchyme, Precursor cell and NeuroD. In his study, which falls under the umbrella issue of Pancreas, Transcription is strongly linked to Transcription factor. His Molecular biology research focuses on subjects like Monoclonal antibody, which are linked to Fusion protein and Polyclonal antibodies.
His primary areas of study are Cell biology, Notch signaling pathway, Progenitor cell, Pancreas and HES1. His biological study spans a wide range of topics, including Embryonic stem cell, Induced pluripotent stem cell, Transcription factor, Cell fate determination and Compartment. His Embryonic stem cell study combines topics from a wide range of disciplines, such as Wnt signaling pathway, Cellular differentiation and Embryo, Embryogenesis.
The concepts of his Induced pluripotent stem cell study are interwoven with issues in Promoter and Enteroendocrine cell. His Pancreas research is multidisciplinary, relying on both Bioinformatics, Gene expression profiling, JAG1, Cell subpopulations and Signal transduction. Palle Serup works mostly in the field of HES1, limiting it down to topics relating to Morphogenesis and, in certain cases, Dysgenesis, Downregulation and upregulation, Ectopic pancreas and Pancreas morphogenesis, as a part of the same area of interest.
Palle Serup mostly deals with Cell biology, Embryonic stem cell, Stem cell, Cellular differentiation and Embryogenesis. Much of his study explores Cell biology relationship to Cell fate determination. His Cell fate determination research includes elements of Molecular biology, GABAergic, RBPJ and Synexpression.
The Stem cell study combines topics in areas such as Induced pluripotent stem cell, Directed differentiation and Embryoid body. His Extracellular matrix research integrates issues from Progenitor cell, Pancreas, Mechanotransduction, Integrin and Signal transduction. His Wnt signaling pathway study incorporates themes from Cell polarity, Gastrulation, NODAL and Brachyury.
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Control of endodermal endocrine development by Hes-1.
J Jensen;E E Pedersen;P Galante;J Hald.
Nature Genetics (2000)
Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
J. Briscoe;L. Sussel;P. Serup;D. Hartigan-O'Connor.
Opposing actions of Arx and Pax4 in endocrine pancreas development
Patrick Collombat;Ahmed Mansouri;Jacob Hecksher-Sørensen;Palle Serup.
Genes & Development (2003)
Lower blood glucose, hyperglucagonemia, and pancreatic α cell hyperplasia in glucagon receptor knockout mice
R. W. Gelling;X. Q. Du;D. S. Dichmann;J. Rømer.
Proceedings of the National Academy of Sciences of the United States of America (2003)
The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells
Patrick Collombat;Xiaobo Xu;Philippe Ravassard;Philippe Ravassard;Beatriz Sosa-Pineda.
Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation.
J Jensen;R S Heller;T Funder-Nielsen;E E Pedersen.
An illustrated review of early pancreas development in the mouse.
Mette Christine Jørgensen;Jonas Ahnfelt-Rønne;Jacob Hald;Ole D. Madsen.
Endocrine Reviews (2007)
Embryonic endocrine pancreas and mature β cells acquire α and PP cell phenotypes upon Arx misexpression
Patrick Collombat;Jacob Hecksher-Sorensen;Jens Krull;Joachim Berger.
Journal of Clinical Investigation (2007)
Artifactual Insulin Release From Differentiated Embryonic Stem Cells
Mattias Hansson;Anna Tonning;Ulrik Frandsen;Andreas Petri.
Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3
Yves Heremans;Mark Van De Casteele;Peter in't Veld;Gerard Gradwohl.
Journal of Cell Biology (2002)
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