World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
15796
World Ranking
9121
National Ranking
89

Overview

Palle Serup is affiliated with the University of Copenhagen in Denmark and conducts research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields with notable focus on Molecular Biology, Surgery, and Genetics, alongside areas like Hepatology and Pediatrics, Perinatology, and Child Health.

The scientist's research topics cover a diverse range of biomedical subjects, including:

  • Pancreatic function and diabetes
  • Pluripotent Stem Cells Research
  • Diabetes and associated disorders
  • Congenital heart defects research
  • Liver physiology and pathology
  • Genetics and Neurodevelopmental Disorders
  • Renal and related cancers

Among the recent published papers by Palle Serup are:

  • "Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors," 2020, Developmental Cell
  • "Dynamic cell contacts between periportal mesenchyme and ductal epithelium act as a rheostat for liver cell proliferation," 2021, Cell stem cell
  • "Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling," 2022, Nature Communications
  • "Extensive NEUROG3 occupancy in the human pancreatic endocrine gene regulatory network," 2021, Molecular Metabolism
  • "Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development," 2020, Development

The frequent coauthors collaborating with Palle Serup include:

  • Philip A. Seymour
  • Kristian Honnens de Lichtenberg
  • Anuska la Rosa Egeskov-Madsen
  • Mette C. Jørgensen
  • Yi Miao

Palle Serup's publications often appear in journals such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Development
  • Developmental Cell
  • Cell stem cell

Best Publications

  • Control of endodermal endocrine development by Hes-1.

    J Jensen;E E Pedersen;P Galante;J Hald

  • Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

    J. Briscoe;L. Sussel;P. Serup;D. Hartigan-O'Connor

  • Opposing actions of Arx and Pax4 in endocrine pancreas development

    Patrick Collombat;Ahmed Mansouri;Jacob Hecksher-Sørensen;Palle Serup

  • The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells

    Patrick Collombat;Xiaobo Xu;Philippe Ravassard;Philippe Ravassard;Beatriz Sosa-Pineda

  • Lower blood glucose, hyperglucagonemia, and pancreatic α cell hyperplasia in glucagon receptor knockout mice

    R. W. Gelling;X. Q. Du;D. S. Dichmann;J. Rømer

  • Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation.

    J Jensen;R S Heller;T Funder-Nielsen;E E Pedersen

  • An illustrated review of early pancreas development in the mouse.

    Mette Christine Jørgensen;Jonas Ahnfelt-Rønne;Jacob Hald;Ole D. Madsen

  • Conditional and specific NF-κB blockade protects pancreatic beta cells from diabetogenic agents

    R. Eldor;A. Yeffet;K. Baum;V. Doviner

  • Embryonic endocrine pancreas and mature β cells acquire α and PP cell phenotypes upon Arx misexpression

    Patrick Collombat;Jacob Hecksher-Sorensen;Jens Krull;Joachim Berger

  • Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3

    Yves Heremans;Mark Van De Casteele;Peter in't Veld;Gerard Gradwohl

  • Artifactual Insulin Release From Differentiated Embryonic Stem Cells

    Mattias Hansson;Anna Tonning;Ulrik Frandsen;Andreas Petri

  • Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development

    Jacob Hald;J.Peter Hjorth;Michael S German;Ole D Madsen

  • The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas.

    Patrick Collombat;Jacob Hecksher-Sørensen;Vania Broccoli;Jens Krull

  • Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes

    Helle V. Petersen;Palle Serup;James Leonard;Birgitte K. Michelsen

  • The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells.

    A Ammendrup;A Maillard;K Nielsen;N Aabenhus Andersen

  • mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor

    Jan Jensen;Palle Serup;Christina Karlsen;Tove Funder Nielsen

  • Genetic determinants of pancreatic epsilon-cell development.

    R. S. Heller;M. Jenny;P. Collombat;A. Mansouri

  • The Insulin Gene Promoter: A Simplified Nomenclature

    German M;Ashcroft S;Docherty K;Edlund H

  • Anteroposterior polarity and elongation in the absence of extra-embryonic tissues and of spatially localised signalling in gastruloids: mammalian embryonic organoids.

    David A Turner;Mehmet Girgin;Luz Alonso-Crisostomo;Vikas Trivedi

  • Mechanosignalling via integrins directs fate decisions of pancreatic progenitors

    Anant Mamidi;Christy Prawiro;Philip A. Seymour;Kristian Honnens de Lichtenberg

Frequent Co-Authors

Jan Jensen
Jan Jensen Cleveland Clinic
Harry Heimberg
Harry Heimberg Vrije Universiteit Brussel
Ahmed Mansouri
Ahmed Mansouri Max Planck Society
Poul Hyttel
Poul Hyttel University of Copenhagen
Ryoichiro Kageyama
Ryoichiro Kageyama Kyoto University
Mark A. Magnuson
Mark A. Magnuson Vanderbilt University
Itaru Imayoshi
Itaru Imayoshi Kyoto University
Christopher V.E. Wright
Christopher V.E. Wright Vanderbilt University
Henrik Semb
Henrik Semb University of Copenhagen
Raphael Kopan
Raphael Kopan Cincinnati Children's Hospital Medical Center

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