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Molecular Biology

D-Index
45
Citations
11121
World Ranking
2840
National Ranking
1360

Overview

Jan Jensen is affiliated with the Cleveland Clinic in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, their subfields of focus are:

  • Molecular Biology
  • Genetics
  • Artificial Intelligence
  • Surgery
  • Biomedical Engineering

Jensen's work covers a range of topics, predominantly:

  • Machine Learning in Healthcare
  • Pluripotent Stem Cells Research
  • Biomedical Text Mining and Ontologies
  • Genomics and Rare Diseases
  • RNA modifications and cancer
  • Pancreatic function and diabetes
  • 3D Printing in Biomedical Research

The frequent publication venues where their research appears include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • iScience
  • Stem Cell Research & Therapy
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nature

Among Jan Jensen's recent published papers are:

  • "High-Dimensional Design-Of-Experiments Extracts Small-Molecule-Only Induction Conditions for Dorsal Pancreatic Endoderm from Pluripotency," 2020, iScience
  • "Semantic text mining in early drug discovery for type 2 diabetes," 2020, PLoS ONE
  • "Structural variation in 1,019 diverse humans based on long-read sequencing," 2025, Nature
  • "Imputation of structural variants using a multi-ancestry long-read sequencing panel enables identification of disease associations," 2023, bioRxiv (Cold Spring Harbor Laboratory)
  • "Controlling neural territory patterning from pluripotency using a systems developmental biology approach," 2022, iScience

The scientist frequently collaborates with the following co-authors:

  • A. Mesut Erzurumluoglu
  • Michael A. Bukys
  • Jatin Arora
  • Zhihao Ding
  • Johann de Jong

Best Publications

  • Control of endodermal endocrine development by Hes-1.

    J Jensen;E E Pedersen;P Galante;J Hald

  • The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

    Janet M. Wenzlau;Kirstine Juhl;Kirstine Juhl;Liping Yu;Ong Moua

  • SOX9 is required for maintenance of the pancreatic progenitor cell pool

    Philip A. Seymour;Kristine K. Freude;Man N. Tran;Erin E. Mayes

  • Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium

    Marjorie Jenny;Céline Uhl;Colette Roche;Isabelle Duluc

  • Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation.

    J Jensen;R S Heller;T Funder-Nielsen;E E Pedersen

  • Gene regulatory factors in pancreatic development

    Jan Jensen

  • Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration

    Jan Nygaard Jensen;Erin Cameron;Maria Veronica R. Garay;Thomas W. Starkey

  • Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3.

    Patrick Jacquemin;Serge M. Durviaux;Jan Jensen;Catherine Godfraind

  • Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas

    Meritxell Rovira;Sherri Gae Scott;Andrew S. Liss;Jan Jensen

  • Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development

    Jacob Hald;J.Peter Hjorth;Michael S German;Ole D Madsen

  • FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development

    Gitte Anker Norgaard;Jan Nygaard Jensen;Jan Jensen

  • mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor

    Jan Jensen;Palle Serup;Christina Karlsen;Tove Funder Nielsen

  • Hedgehog Signaling Is Required for Effective Regeneration of Exocrine Pancreas

    Volker Fendrich;Volker Fendrich;Farzad Esni;Maria Veronica R. Garay;Georg Feldmann

  • Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function

    Sui Wang;Jan N. Jensen;Philip A. Seymour;Wei Hsu

  • Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation

    R. Scott Heller;Darwin S. Dichmann;Jan Jensen;Chris Miller

  • Diminished β-cell replication contributes to reduced β-cell mass in fetal sheep with intrauterine growth restriction

    Sean W. Limesand;Jan Jensen;John C. Hutton;William W. Hay

  • Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1.

    Palle Serup;Jan Jensen;Frank G. Andersen;Mette C. Jorgensen

  • Permanent Neonatal Diabetes and Enteric Anendocrinosis Associated With Biallelic Mutations in NEUROG3

    Oscar Rubio-Cabezas;Jan N. Jensen;Maria I. Hodgson;Ethel Codner

  • Rat Endocrine Pancreatic Development in Relation to Two Homeobox Gene Products (Pdx-1 and Nkx 6.1)

    Anne Øster;Jan Jensen;Palle Serup;Philip Galante

  • Transcription Factor Glis3, a Novel Critical Player in the Regulation of Pancreatic β-Cell Development and Insulin Gene Expression

    Hong Soon Kang;Yong Sik Kim;Gary ZeRuth;Ju Youn Beak

Frequent Co-Authors

Palle Serup
Palle Serup University of Copenhagen
John C. Hutton
John C. Hutton University of Colorado Denver
Anton M. Jetten
Anton M. Jetten National Institutes of Health
Maike Sander
Maike Sander Max Delbrück Center for Molecular Medicine
Frédéric P. Lemaigre
Frédéric P. Lemaigre Université Catholique de Louvain
James DeGregori
James DeGregori University of Colorado Anschutz Medical Campus
François Guillemot
François Guillemot The Francis Crick Institute
Justin D. Lathia
Justin D. Lathia Cleveland Clinic Lerner College of Medicine
Raymond J. MacDonald
Raymond J. MacDonald The University of Texas Southwestern Medical Center
Gerd Scherer
Gerd Scherer University of Freiburg

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