Graham Simmons

Overview

Best Publications

• Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry

  Graham Simmons;Jacqueline D. Reeves;Andrew J. Rennekamp;Sean M. Amberg

  682
  Citations

• A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus

  Thomas N. Kledal;Mette M. Rosenkilde;Florence Coulin;Graham Simmons

  602
  Citations

• Aminooxypentane-RANTES Induces CCR5 Internalization but Inhibits Recycling: A Novel Inhibitory Mechanism of HIV Infectivity

  Matthias Mack;Bruno Luckow;Peter J. Nelson;Josef Cihak

  543
  Citations

• Differential Downregulation of ACE2 by the Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63

  Ilona Glowacka;Stephanie Bertram;Petra Herzog;Susanne Pfefferle

  515
  Citations

• Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry.

  G Simmons;D Wilkinson;J D Reeves;M T Dittmar

  499
  Citations

• The Spike Protein of the Emerging Betacoronavirus EMC Uses a Novel Coronavirus Receptor for Entry, Can Be Activated by TMPRSS2, and Is Targeted by Neutralizing Antibodies

  Stefanie Gierer;Stephanie Bertram;Franziska Kaup;Florian Wrensch

  395
  Citations

• KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells

  Johnny T. Stine;Christi Wood;Mark Hill;Angela Epp

  279
  Citations

• Ebola Virus Glycoproteins Induce Global Surface Protein Down-Modulation and Loss of Cell Adherence

  Graham Simmons;Rouven J. Wool-Lewis;Frédéric Baribaud;Robert C. Netter

  273
  Citations

• Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent.

  Aine McKnight;David Wilkinson;G Simmons;Simon Talbot

  247
  Citations

• Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress

  Julie M. Fox;Feng Long;Melissa A. Edeling;Hueylie Lin

  230
  Citations

• CXCR4 as a functional coreceptor for human immunodeficiency virus type 1 infection of primary macrophages

  Graham Simmons;Jacqueline D. Reeves;Áine McKnight;Nathalie Dejucq

  211
  Citations

• Primary human immunodeficiency virus type 2 (HIV-2) isolates infect CD4-negative cells via CCR5 and CXCR4: comparison with HIV-1 and simian immunodeficiency virus and relevance to cell tropism in vivo.

  Jacqueline D. Reeves;Sam Hibbitts;Graham Simmons;Áine McKnight

  208
  Citations

• CD4-independent infection by HIV-2 (ROD/B): use of the 7-transmembrane receptors CXCR-4, CCR-3, and V28 for entry.

  Jacqueline D. Reeves;Áine McKnight;Sandra Potempa;Graham Simmons

  197
  Citations

• Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry.

  Zhaozhu Qiu;Susan T. Hingley;Graham Simmons;Christopher Yu

  191
  Citations

• A Single Asparagine-Linked Glycosylation Site of the Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein Facilitates Inhibition by Mannose-Binding Lectin through Multiple Mechanisms

  Yanchen Zhou;Kai Lu;Susanne Pfefferle;Stephanie Bertram

  187
  Citations

• HIV-1 tropism and co-receptor use

  Matthias T. Dittmar;Áine McKnight;Graham Simmons;Paul R. Clapham

  178
  Citations

• Multiple extracellular domains of CCR-5 contribute to human immunodeficiency virus type 1 entry and fusion.

  Laurent Picard;Graham Simmons;Christine A. Power;Alexandra Meyer

  176
  Citations

• No Evidence of Murine-Like Gammaretroviruses in CFS Patients Previously Identified as XMRV-Infected

  Konstance Knox;Donald Carrigan;Graham Simmons;Graham Simmons;Fernando Teque

  164
  Citations

• Highly Conserved Regions within the Spike Proteins of Human Coronaviruses 229E and NL63 Determine Recognition of Their Respective Cellular Receptors

  Heike Hofmann;Graham Simmons;Graham Simmons;Andrew J. Rennekamp;Chawaree Chaipan

  154
  Citations

• Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion.

  Graham Simmons;Stephanie Bertram;Ilona Glowacka;Imke Steffen

  145
  Citations