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James DeGregori

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
30344
World Ranking
5463
National Ranking
2593

James DeGregori publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where James DeGregori sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 232 publications — 62nd percentile

62% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

James DeGregori D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where James DeGregori sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 74 D-Index — 72nd percentile

72% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

James DeGregori is affiliated with the University of Colorado Anschutz Medical Campus in the United States. Their research spans multiple areas within medicine and molecular biology, focusing heavily on cancer and hematology.

DeGregori's scientific contributions cover a broad range of topics, with notable emphasis on:

  • Cancer Genomics and Diagnostics
  • Acute Myeloid Leukemia Research
  • Hematopoietic Stem Cell Transplantation
  • Evolution and Genetic Dynamics
  • Epigenetics and DNA Methylation
  • Single-cell and Spatial Transcriptomics
  • Cancer Cells and Metastasis

Their work is published predominantly in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Subfields of study include Molecular Biology, Hematology, Cancer Research, Oncology, and Genetics.

DeGregori's recent publications demonstrate engagement with contemporary cancer research topics. Among the noteworthy papers are:

  • "Embracing cancer complexity: Hallmarks of systemic disease," 2024, Cell
  • "Cancer as a disease of old age: changing mutational and microenvironmental landscapes," 2020, British Journal of Cancer
  • "Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells," 2020, Cell Stem Cell
  • "Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion," 2021, Proceedings of the National Academy of Sciences
  • "Clonal hematopoiesis: Mutation-specific adaptation to environmental change," 2022, Cell Stem Cell

The number of citations for these papers indicates their relevance in the field, with counts ranging from over 100 to more than 300 citations.

Frequent co-authors with whom DeGregori has collaborated include:

  • Eric M. Pietras (14 co-authored works)
  • Marco De Dominici (10 co-authored works)
  • Andrew Goodspeed (10 co-authored works)
  • Edward J. Evans (9 co-authored works)
  • Frédéric Thomas (8 co-authored works)

Leading journals and venues featuring DeGregori's research include:

  • Cancer Research (21 publications)
  • Blood (9 publications)
  • Aging and Cancer (5 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (5 preprints)
  • Evolutionary Applications (4 publications)

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes.

    James DeGregori;Timothy Kowalik;Joseph R. Nevins

  • Distinct roles for E2F proteins in cell growth control and apoptosis

    James DeGregori;Gustavo Leone;Alexander Miron;Laszlo Jakoi

  • Regulation of the cyclin E gene by transcription factor E2F1.

    K Ohtani;J DeGregori;J R Nevins

  • Distinct and Overlapping Roles for E2F Family Members in Transcription, Proliferation and Apoptosis

    James DeGregori;David G. Johnson

  • Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F

    Gustavo Leone;James DeGregori;Rosalie Sears;Laszlo Jakoi

  • Ras Enhances Myc Protein Stability

    Rosalie Sears;Gustavo Leone;James DeGregori;Joseph R Nevins

  • E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

    Timothy F. Kowalik;James DeGregori;James K. Schwarz;Joseph R. Nevins

  • Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.

    Samir N. Khleif;James Degregori;Carole L. Yee;Gregory A. Otterson

  • Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells.

    Courtney L. Jones;Brett M. Stevens;Angelo D'Alessandro;Julie A. Reisz

  • E2F3 activity is regulated during the cell cycle and is required for the induction of S phase

    Gustavo Leone;James DeGregori;Zhen Yan;Laszlo Jakoi

  • The genetics of the E2F family of transcription factors: shared functions and unique roles.

    James DeGregori

  • The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state.

    E J Smith;G Leone;J DeGregori;L Jakoi

  • Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells

    Zhen Yan;James DeGregori;Ralph Shohet;Gustavo Leone

  • The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease

    Günter U. Höglinger;Joshua J. Breunig;Candan Depboylu;Caroline Rouaux

  • E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity.

    James DeGregori;Gustavo Leone;Kiyoshi Ohtani;Alexander Miron

  • Trisomy 21 consistently activates the interferon response.

    Kelly D Sullivan;Hannah C Lewis;Amanda A Hill;Ahwan Pandey

  • Role of the Rb/E2F pathway in cell growth control.

    Joseph R. Nevins;Gustavo Leone;James DeGregori;Laszlo Jakoi

  • E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2

    TF Kowalik;J DeGregori;G Leone;L Jakoi

  • TNF-α–driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging

    Pavel Davizon-Castillo;Brandon McMahon;Sonia Aguila;David Bark

Frequent Co-Authors

Joseph R. Nevins
Joseph R. Nevins Duke University
Aik Choon Tan
Aik Choon Tan University of Utah
Gustavo Leone
Gustavo Leone Medical University of South Carolina
Angelo D'Alessandro
Angelo D'Alessandro University of Colorado Denver
Craig T. Jordan
Craig T. Jordan University of Colorado Anschutz Medical Campus
Travis Nemkov
Travis Nemkov University of Colorado Denver
Kirk C. Hansen
Kirk C. Hansen University of Colorado Anschutz Medical Campus
Charles A. Dinarello
Charles A. Dinarello University of Colorado Anschutz Medical Campus
Timm Schroeder
Timm Schroeder ETH Zurich
Lynn E. Heasley
Lynn E. Heasley University of Colorado Anschutz Medical Campus

External Links

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Best Scientists Citing James DeGregori

Joseph R. Nevins

Joseph R. Nevins

Duke University

Publications: 57

Gustavo Leone

Gustavo Leone

Medical University of South Carolina

Publications: 48

David T. Curiel

David T. Curiel

Washington University in St. Louis

Publications: 45

Beata Ujvari

Beata Ujvari

Deakin University

Publications: 36

Joaquín M. Espinosa

Joaquín M. Espinosa

University of Colorado Anschutz Medical Campus

Publications: 34

Judith Campisi

Judith Campisi

Buck Institute for Research on Aging

Publications: 31

Nicholas J. Dyson

Nicholas J. Dyson

Harvard University

Publications: 30

Frédéric Thomas

Frédéric Thomas

University of Montpellier

Publications: 30

Tyler Jacks

Tyler Jacks

MIT

Publications: 25

Kristian Helin

Kristian Helin

Institute of Cancer Research

Publications: 24

Akseli Hemminki

Akseli Hemminki

University of Helsinki

Publications: 23

Hartmut Geiger

Hartmut Geiger

University of Ulm

Publications: 23

Toshinori Nakayama

Toshinori Nakayama

Chiba University

Publications: 22

Kelly M. McMasters

Kelly M. McMasters

University of Louisville

Publications: 22

Jean Y. J. Wang

Jean Y. J. Wang

University of California, San Diego

Publications: 21

Angelo D'Alessandro

Angelo D'Alessandro

University of Colorado Denver

Publications: 21

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