2013 - Member of Academia Europaea
Member of the European Molecular Biology Organization (EMBO)
His primary scientific interests are in Genetics, PRC2, Molecular biology, Cell biology and E2F. His PRC2 study integrates concerns from other disciplines, such as Embryonic stem cell, Cellular differentiation, Gene silencing and SUZ12. His Molecular biology research is multidisciplinary, incorporating elements of Cyclin-dependent kinase, Cyclin A2, Cyclin D, Cyclin B and EZH2.
The Cell biology study combines topics in areas such as Cyclin A and DNA replication. His E2F study combines topics in areas such as Tumor suppressor gene, Retinoblastoma protein and Cancer research. The study incorporates disciplines such as Chromatin and Transcriptional regulation in addition to Histone.
Kristian Helin focuses on Cell biology, Cancer research, Molecular biology, Genetics and Chromatin. His work deals with themes such as Histone, Transcription factor, Gene expression, Gene and PRC2, which intersect with Cell biology. His work in Transcription factor tackles topics such as Retinoblastoma protein which are related to areas like Tumor suppressor gene.
His study looks at the relationship between Cancer research and fields such as Cellular differentiation, as well as how they intersect with chemical problems. Kristian Helin interconnects DNA methylation, E2F, Biochemistry, Promoter and Cyclin A in the investigation of issues within Molecular biology. His research in Chromatin intersects with topics in Computational biology, Epigenetics and Signal transduction.
Kristian Helin mainly focuses on Cell biology, Chromatin, Transcription factor, Computational biology and Cancer research. His Cell biology research is multidisciplinary, incorporating perspectives in Gene expression, Transcriptional regulation, Regulation of gene expression, Gene and Histone. His research integrates issues of Histone H2A, Polycomb-group proteins and Monoubiquitination in his study of Regulation of gene expression.
His studies deal with areas such as Transcription and Epigenetics as well as Chromatin. Kristian Helin studies Repressor, a branch of Transcription factor. His Cancer research study combines topics from a wide range of disciplines, such as Cancer, Cell culture, Methylation, GLI2 and In vivo.
Kristian Helin mainly investigates Cell biology, Epigenetics, Chromatin, DNA methylation and Methylation. Kristian Helin has included themes like Regulation of gene expression and Histone in his Cell biology study. His Regulation of gene expression research entails a greater understanding of Gene.
His Epigenetics research focuses on EZH2 and PRC2. His Chromatin study incorporates themes from Transcription factor and Computational biology. His studies in Methylation integrate themes in fields like Cancer research, Myeloid leukemia, Transcription, Transcriptional regulation and PRC1.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
Adrian P. Bracken;Nikolaj Dietrich;Diego Pasini;Klaus H. Hansen.
Genes & Development (2006)
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.
Karl Agger;Paul A. C. Cloos;Jesper Christensen;Diego Pasini.
EZH2 is downstream of the pRB‐E2F pathway, essential for proliferation and amplified in cancer
Adrian P. Bracken;Diego Pasini;Maria Capra;Elena Prosperini.
The EMBO Journal (2003)
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
Kristine Williams;Jesper Christensen;Marianne Terndrup Pedersen;Jens V. Johansen.
Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
Diego Pasini;Adrian P Bracken;Michael R Jensen;Eros Lazzerini Denchi.
The EMBO Journal (2004)
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
Adrian P. Bracken;Daniela Kleine-Kohlbrecher;Nikolaj Dietrich;Diego Pasini.
Genes & Development (2007)
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis
Heiko Müller;Adrian P. Bracken;Richard Vernell;M. Cristina Moroni.
Genes & Development (2001)
Transcriptional regulation by Polycomb group proteins.
Luciano Di Croce;Luciano Di Croce;Kristian Helin.
Nature Structural & Molecular Biology (2013)
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
Paul A C Cloos;Jesper Christensen;Karl Agger;Alessio Maiolica.
Molecular mechanisms and potential functions of histone demethylases.
Susanne Marije Kooistra;Kristian Helin.
Nature Reviews Molecular Cell Biology (2012)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: