What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Genetics, PRC2, Molecular biology, Cell biology and E2F.
His PRC2 study integrates concerns from other disciplines, such as Embryonic stem cell, Cellular differentiation, Gene silencing and SUZ12.
His Molecular biology research is multidisciplinary, incorporating elements of Cyclin-dependent kinase, Cyclin A2, Cyclin D, Cyclin B and EZH2.
The Cell biology study combines topics in areas such as Cyclin A and DNA replication.
His E2F study combines topics in areas such as Tumor suppressor gene, Retinoblastoma protein and Cancer research.
The study incorporates disciplines such as Chromatin and Transcriptional regulation in addition to Histone.
His most cited work include:
- Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions (1064 citations)
- UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. (994 citations)
- EZH2 is downstream of the pRB‐E2F pathway, essential for proliferation and amplified in cancer (940 citations)
What are the main themes of his work throughout his whole career to date?
Kristian Helin focuses on Cell biology, Cancer research, Molecular biology, Genetics and Chromatin.
His work deals with themes such as Histone, Transcription factor, Gene expression, Gene and PRC2, which intersect with Cell biology.
His work in Transcription factor tackles topics such as Retinoblastoma protein which are related to areas like Tumor suppressor gene.
His study looks at the relationship between Cancer research and fields such as Cellular differentiation, as well as how they intersect with chemical problems.
Kristian Helin interconnects DNA methylation, E2F, Biochemistry, Promoter and Cyclin A in the investigation of issues within Molecular biology.
His research in Chromatin intersects with topics in Computational biology, Epigenetics and Signal transduction.
He most often published in these fields:
- Cell biology (45.21%)
- Cancer research (27.39%)
- Molecular biology (25.74%)
What were the highlights of his more recent work (between 2018-2021)?
- Cell biology (45.21%)
- Chromatin (26.07%)
- Transcription factor (22.44%)
In recent papers he was focusing on the following fields of study:
Kristian Helin mainly focuses on Cell biology, Chromatin, Transcription factor, Computational biology and Cancer research.
His Cell biology research is multidisciplinary, incorporating perspectives in Gene expression, Transcriptional regulation, Regulation of gene expression, Gene and Histone.
His research integrates issues of Histone H2A, Polycomb-group proteins and Monoubiquitination in his study of Regulation of gene expression.
His studies deal with areas such as Transcription and Epigenetics as well as Chromatin.
Kristian Helin studies Repressor, a branch of Transcription factor.
His Cancer research study combines topics from a wide range of disciplines, such as Cancer, Cell culture, Methylation, GLI2 and In vivo.
Between 2018 and 2021, his most popular works were:
- Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation (152 citations)
- Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation (152 citations)
- Non-core Subunits of the PRC2 Complex Are Collectively Required for Its Target-Site Specificity (35 citations)
In his most recent research, the most cited papers focused on:
Kristian Helin mainly investigates Cell biology, Epigenetics, Chromatin, DNA methylation and Methylation.
Kristian Helin has included themes like Regulation of gene expression and Histone in his Cell biology study.
His Regulation of gene expression research entails a greater understanding of Gene.
His Epigenetics research focuses on EZH2 and PRC2.
His Chromatin study incorporates themes from Transcription factor and Computational biology.
His studies in Methylation integrate themes in fields like Cancer research, Myeloid leukemia, Transcription, Transcriptional regulation and PRC1.
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