World's Best Scientists 2026 revealed!
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Genetics
Italy
2026
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Molecular Biology
Italy
2026

D-Index & Metrics

Genetics

D-Index
115
Citations
48364
World Ranking
455
National Ranking
3

Molecular Biology

D-Index
115
Citations
48364
World Ranking
310
National Ranking
5

Medicine

D-Index
115
Citations
49225
World Ranking
4543
National Ranking
139

Research.com Recognitions

  • 2026 - Research.com Genetics in Italy Leader Award
  • 2026 - Research.com Molecular Biology in Italy Leader Award
  • 2025 - Research.com Genetics in Italy Leader Award
  • 2025 - Research.com Molecular Biology in Italy Leader Award
  • 2024 - Research.com Genetics in Italy Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Italy Leader Award
  • 2023 - Research.com Genetics in Italy Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in Italy Leader Award
  • 2023 - Research.com Medicine in Italy Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Italy Leader Award

Overview

Alfredo Fusco is affiliated with the University of Naples Federico II in Italy. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Fusco's work focuses on molecular biology, cancer research, surgery, oncology, and pathology and forensic medicine as subfields.

The scientist's research topics cover several key areas including:

  • Cancer-related molecular mechanisms research
  • RNA research and splicing
  • Circular RNAs in diseases
  • Genomics and chromatin dynamics
  • RNA modifications and cancer
  • Cancer-related gene regulation
  • Testicular diseases and treatments

Alfredo Fusco has contributed to multiple scientific publications, notably including:

  • "The Long Non-Coding RNA Prader Willi/Angelman Region RNA5 (PAR5) Is Downregulated in Anaplastic Thyroid Carcinomas Where It Acts as a Tumor Suppressor by Reducing EZH2 Activity", 2020, Cancers
  • "HMGA1-Regulating microRNAs Let-7a and miR-26a are Downregulated in Human Seminomas", 2020, International Journal of Molecular Sciences
  • "Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assays", 2020, Scientific Reports
  • "Interplay between HMGA and TP53 in cell cycle control along tumor progression", 2020, Cellular and Molecular Life Sciences
  • "Critical role of the high mobility group A proteins in hematological malignancies", 2021, Hematological Oncology

The primary venues where Fusco frequently publishes include Cell Cycle, Cancers, Scientific Reports, International Journal of Molecular Sciences, and Cellular and Molecular Life Sciences.

Fusco has collaborated extensively with other researchers. Frequent co-authors include:

  • Marco De Martino
  • Francesco Esposito
  • Pierlorenzo Pallante
  • Paolo Chieffi
  • Simona Pellecchia

Best Publications

  • BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas

    Marina N. Nikiforova;Edna Teruko Kimura;Manoj Gandhi;Paul W. Biddinger

  • PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas.

    Michele Grieco;Massimo Santoro;Maria Teresa Berlingieri;Rosa Marina Melillo

  • Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

    M Santoro;F Carlomagno;A Romano;D P Bottaro

  • Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27 Kip1 by PKB/Akt-mediated phosphorylation in breast cancer

    Giuseppe Viglietto;Maria Letizia Motti;Paola Bruni;Rosa Marina Melillo

  • Roles of HMGA proteins in cancer.

    Alfredo Fusco;Monica Fedele

  • ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases.

    Francesca Carlomagno;Donata Vitagliano;Teresa Guida;Fortunato Ciardiello

  • MicroRNA deregulation in human thyroid papillary carcinomas

    P Pallante;R Visone;R Visone;Manuela Ferracin;A Ferraro

  • Regulation of Thyroid Cell Proliferation by TSH and Other Factors: A Critical Evaluation of in Vitro Models

    Takao Kimura;Alexandra Van Keymeulen;Jacqueline Golstein;Alfredo Fusco

  • MicroRNAs (miR)-221 and miR-222, both overexpressed in human thyroid papillary carcinomas, regulate p27Kip1 protein levels and cell cycle.

    Rosa Visone;Lucia Russo;Pierlorenzo Pallante;Ivana De Martino

  • A new oncogene in human thyroid papillary carcinomas and their lymph-nodal metastases

    A. Fusco;M. Grieco;M. Santoro;M. T. Berlingieri

  • Bioactive IL-18 expression is up-regulated in Crohn's disease.

    Giovanni Monteleone;Francesco Trapasso;Tiziana Parrello;Livia Biancone

  • Molecular characterization of RET/PTC3; A novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma

    Massimo Santoro;Nina A. Dathan;Maria T. Berlingieri;Italia Bongarzone

  • Specific microRNAs are downregulated in human thyroid anaplastic carcinomas.

    R. Visone;P. Pallante;A. Vecchione;R. Cirombella

  • Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.

    M Santoro;F Carlomagno;I D Hay;M A Herrmann

  • The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

    Rosa Marina Melillo;Maria Domenica Castellone;Valentina Guarino;Valentina De Falco

  • Mutation of the PIK3CA gene in anaplastic thyroid cancer.

    Ginesa García-Rostán;Angela M. Costa;Isabel Pereira-Castro;Giuliana Salvatore

  • Increased BDNF promoter methylation in the Wernicke area of suicide subjects.

    Simona Keller;Marco Sarchiapone;Federica Zarrilli;Alja Videtič

  • An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue.

    N Abe;T Watanabe;Y Suzuki;N Matsumoto

  • High level expression of the HMGI (Y) gene during embryonic development.

    Gennaro Chiappetta;Virginia Avantaggiato;Roberta Visconti;Monica Fedele

  • The RET receptor: function in development and dysfunction in congenital malformation

    Serge Manié;Massimo Santoro;Alfredo Fusco;Marc Billaud

Frequent Co-Authors

Monica Fedele
Monica Fedele National Research Council (CNR)
Massimo Santoro
Massimo Santoro University of Padua
Giuseppe Viglietto
Giuseppe Viglietto Magna Graecia University
Massimo Santoro
Massimo Santoro University of Naples Federico II
Carlo M. Croce
Carlo M. Croce The Ohio State University
Rosa Marina Melillo
Rosa Marina Melillo University of Naples Federico II
Lorenzo Chiariotti
Lorenzo Chiariotti University of Naples Federico II
Claudio Arra
Claudio Arra Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
Paola Bruni
Paola Bruni University of Florence
Guidalberto Manfioletti
Guidalberto Manfioletti University of Trieste

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