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D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
10728
World Ranking
12136
National Ranking
362

Overview

Monica Fedele is affiliated with the National Research Council (CNR) in Italy, contributing extensively to research in biochemistry, genetics, and molecular biology, with additional work spanning medicine. The scientist's publication record reflects a consistent focus on molecular biology and oncology, with specialization in cancer research and biomedical engineering.

The research output includes numerous papers published in well-known scientific venues. Frequent publication venues for this scientist include the International Journal of Molecular Sciences, Journal of Experimental & Clinical Cancer Research, Pharmaceutics, Cancers, and Cells.

Key research topics covered encompass advanced biosensing and bioanalysis techniques, cancer cells and metastasis, nanoplatforms for cancer theranostics, epigenetics and DNA methylation, RNA interference and gene delivery, cancer, hypoxia, and metabolism, as well as immunotherapy and immune responses.

Notable recent papers include:

  • The Epithelial-Mesenchymal Transition at the Crossroads between Metabolism and Tumor Progression, 2022, International Journal of Molecular Sciences
  • Epithelial-Mesenchymal Transition (EMT) 2021, 2022, International Journal of Molecular Sciences
  • Optimizing cisplatin delivery to triple-negative breast cancer through novel EGFR aptamer-conjugated polymeric nanovectors, 2021, Journal of Experimental & Clinical Cancer Research
  • Epithelial-Mesenchymal Transition (EMT), 2023, International Journal of Molecular Sciences
  • Aptamer targeted therapy potentiates immune checkpoint blockade in triple-negative breast cancer, 2020, Journal of Experimental & Clinical Cancer Research

Frequent coauthors in the scientist's body of work include Laura Cerchia, Simona Camorani, Lisa Agnello, Sabrina Battista, and Antonella Zannetti.

Best Publications

  • Roles of HMGA proteins in cancer.

    Alfredo Fusco;Monica Fedele

  • High level expression of the HMGI (Y) gene during embryonic development.

    Gennaro Chiappetta;Virginia Avantaggiato;Roberta Visconti;Monica Fedele

  • Upregulation of vascular endothelial growth factor (VEGF) and downregulation of placenta growth factor (PlGF) associated with malignancy in human thyroid tumors and cell lines.

    G Viglietto;D Maglione;M Rambaldi;J Cerutti

  • HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity.

    Monica Fedele;Rosa Visone;Ivana De Martino;Giancarlo Troncone

  • The expression of a truncated HMGI-C gene induces gigantism associated with lipomatosis.

    Sabrina Battista;Vincenzo Fidanza;Monica Fedele;Andres J. P. Klein-Szanto

  • Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas.

    Monica Fedele;Monica Fedele;Sabrina Battista;Sabrina Battista;Lawrence Kenyon;Gustavo Baldassarre

  • Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice

    Daniela Foti;Eusebio Chiefari;Monica Fedele;Rodolfo Iuliano

  • Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NFkappaB p65 protein expression.

    Roberta Visconti;Janete Cerutti;Sabrina Battista;Monica Fedele

  • Neoplastic transformation of rat thyroid cells requires the junB and fra‐1 gene induction which is dependent on the HMGI‐C gene product

    Daniela Vallone;Sabrina Battista;Giovanna Maria Pierantoni;Monica Fedele

  • Detection of High Mobility Group I HMGI(Y) Protein in the Diagnosis of Thyroid Tumors: HMGI(Y) Expression Represents a Potential Diagnostic Indicator of Carcinoma

    G. Chiappetta;G. Tallini;M. C. De Biasio;G. Manfioletti

  • Proneural-Mesenchymal Transition: Phenotypic Plasticity to Acquire Multitherapy Resistance in Glioblastoma

    Monica Fedele;Laura Cerchia;Silvia Pegoraro;Riccardo Sgarra

  • Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias.

    Stefania Scala;Giuseppe Portella;Monica Fedele;Gennaro Chiappetta

  • Human colorectal carcinomas express high levels of high mobility group HMGI(Y) proteins.

    Monica Fedele;Antonella Bandiera;Gennaro Chiappetta;Sabrina Battista

  • HMGA and cancer.

    Monica Fedele;Alfredo Fusco

  • Role of the high mobility group A proteins in human lipomas.

    Monica Fedele;Sabrina Battista;Guidalberto Manfioletti;Carlo Maria Croce

  • Altered MicroRNA Expression Profile in Human Pituitary GH Adenomas: Down-Regulation of miRNA Targeting HMGA1, HMGA2, and E2F1

    Daniela D'Angelo;Dario Palmieri;Paula Mussnich;Magali Roche

  • Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.

    Monica Fedele;Francesca Pentimalli;Gustavo Baldassarre;Sabrina Battista

  • Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma

    Gustavo Baldassarre;Sabrina Battista;Sabrina Battista;Barbara Belletti;Sanjay Thakur

  • CBX7 is a tumor suppressor in mice and humans

    Floriana Forzati;Antonella Federico;Pierlorenzo Pallante;Adele Abbate

  • The Epithelial-to-Mesenchymal Transition in Breast Cancer: Focus on Basal-Like Carcinomas

    Monica Fedele;Laura Cerchia;Gennaro Chiappetta

Frequent Co-Authors

Alfredo Fusco
Alfredo Fusco University of Naples Federico II
Claudio Arra
Claudio Arra Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
Carlo M. Croce
Carlo M. Croce The Ohio State University
Giuseppe Viglietto
Giuseppe Viglietto Magna Graecia University
Massimo Santoro
Massimo Santoro University of Naples Federico II
Lorenzo Chiariotti
Lorenzo Chiariotti University of Naples Federico II
Gerardo Botti
Gerardo Botti Istituto Giannina Gaslini
Andres J. P. Klein-Szanto
Andres J. P. Klein-Szanto Fox Chase Cancer Center
Guidalberto Manfioletti
Guidalberto Manfioletti University of Trieste
Renato Franco
Renato Franco University of Campania "Luigi Vanvitelli"

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