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Florence Pedeutour

Florence Pedeutour

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
11200
World Ranking
13261
National Ranking
500

Overview

Florence Pedeutour is affiliated with Grenoble Alpes University in France and has contributed extensively to the intersection of medicine, biochemistry, genetics, and molecular biology. Their research span focuses on oncology and related subfields including pulmonary and respiratory medicine, molecular biology, cancer research, and genetics.

The scientist has developed a significant body of work concentrated on topics related to sarcoma diagnosis and treatment, cardiac tumors and thrombi, glioma diagnosis and treatment, histiocytic disorders and treatments, renal cell carcinoma treatment, cancer genomics and diagnostics, as well as vascular tumors and angiosarcomas.

Frequent publication venues for their research include Genes Chromosomes and Cancer, Histopathology, Journal of Investigative Dermatology, Annales de Dermatologie et de Vénéréologie - FMC, and Cell Death and Differentiation.

Notable recent papers authored or coauthored by Florence Pedeutour include:

  • Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease, 2021, Cell Death and Differentiation
  • Targeting of c-MET and AXL by cabozantinib is a potential therapeutic strategy for patients with head and neck cell carcinoma, 2022, Cell Reports Medicine
  • A polyphenotypic malignant paediatric brain tumour presenting a MN1-PATZ1 fusion, no epigenetic similarities with CNS High-Grade Neuroepithelial Tumour with MN1 Alteration (CNS HGNET-MN1) and related to PATZ1-fused sarcomas, 2020, Neuropathology and Applied Neurobiology
  • Novel Therapeutic Insights in Dedifferentiated Liposarcoma: A Role for FGFR and MDM2 Dual Targeting, 2020, Cancers
  • Comprehensive study of nine novel cases of TFEB-amplified renal cell carcinoma: an aggressive tumour with frequent PDL1 expression, 2022, Histopathology

Collaborations within their research network include partnerships with notable coauthors such as Bérengère Dadone-Montaudie, Ilaria Di Mauro, Damien Ambrosetti, Fanny Burel-Vandenbos, and Valérie Kubiniek.

Best Publications

  • Deregulation of the platelet-derived growth factor B-chain gene via fusion with collagen gene COL1A1 in dermatofibrosarcoma protuberans and giant-cell fibroblastoma

    Marie Pierre Simon;Florence Pedeutour;Nicolas Sirvent;Josiane Grosgeorge

  • Detection of MDM2-CDK4 amplification by fluorescence in situ hybridization in 200 paraffin-embedded tumor samples: utility in diagnosing adipocytic lesions and comparison with immunohistochemistry and real-time PCR.

    Nicolas Sirvent;Jean-Michel Coindre;Georges Maire;Isabelle Hostein

  • Translocation-positive low-grade fibromyxoid sarcoma: clinicopathologic and molecular analysis of a series expanding the morphologic spectrum and suggesting potential relationship to sclerosing epithelioid fibrosarcoma: a study from the French Sarcoma Group.

    Louis Guillou;Jean Benhattar;Carole Gengler;Gabrielle Gallagher

  • Genetics of dermatofibrosarcoma protuberans family of tumors: from ring chromosomes to tyrosine kinase inhibitor treatment.

    Nicolas Sirvent;Georges Maire;Florence Pedeutour

  • Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor.

    Jan Cools;Iwona Wlodarska;Riet Somers;Nicole Mentens

  • Structure of the Supernumerary Ring and Giant Rod Chromosomes in Adipose Tissue Tumors

    Florence Pedeutour;Anne Forus;Jean Michel Coindre;Jeanne Marie Berner

  • Well-differentiated and dedifferentiated liposarcomas

    Jean-Michel Coindre;Florence Pédeutour;Alain Aurias

  • Translocation, t(17;22)(q22;q13), in dermatofibrosarcoma protuberans: a new tumor-associated chromosome rearrangement.

    F. Pedeutour;M.P. Simon;F. Minoletti;G. Barcelo

  • Complex composition and co-amplification of SAS and MDM2 in ring and giant rod marker chromosomes in well-differentiated liposarcoma.

    Florence Pedeutour;Ron F. Suijkerbuijk;Anne Forus;Jose Van Gaal

  • Pseudosarcomatous myofibroblastic proliferations of the bladder : A clinicopathologic study of 42 cases

    Lara R. Harik;Celine Merino;Jean-Michel Coindre;Mahul B. Amin

  • MDM2 and CDK4 immunohistochemistry is a valuable tool in the differential diagnosis of low-grade osteosarcomas and other primary fibro-osseous lesions of the bone

    Fanny Dujardin;Matthieu Bui Nguyen Binh;Corinne Bouvier;Anne Gomez-Brouchet

  • Dermatofibrosarcoma protuberans, giant cell fibroblastoma, and hybrid lesions in children: clinicopathologic comparative analysis of 28 cases with molecular data--a study from the French Federation of Cancer Centers Sarcoma Group.

    Marie-Josée Terrier-Lacombe;Louis Guillou;Georges Maire;Philippe Terrier

  • HMGA2 is the partner of MDM2 in well-differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon.

    Antoine Italiano;Laurence Bianchini;Frédérique Keslair;Stéphanie Bonnafous

  • The architecture and evolution of cancer neochromosomes.

    Dale W. Garsed;Dale W. Garsed;Owen J. Marshall;Vincent D.A. Corbin;Vincent D.A. Corbin;Vincent D.A. Corbin;Arthur Hsu

  • Inflammatory malignant fibrous histiocytomas and dedifferentiated liposarcomas: histological review, genomic profile, and MDM2 and CDK4 status favour a single entity.

    Jean-Michel Coindre;Isabelle Hostein;Georges Maire;Josette Derré

  • Ring 22 chromosomes in dermatofibrosarcoma protuberans are low-level amplifiers of chromosome 17 and 22 sequences.

    Florence Pedeutour;Marie-Pierre Simon;Fabiola Minoletti;Gabriella Sozzi

  • Clinical effect of molecular methods in sarcoma diagnosis (GENSARC): a prospective, multicentre, observational study

    Antoine Italiano;Ilaria Di Mauro;Jocelyn Rapp;Gaëlle Pierron

  • Imatinib mesylate as a preoperative therapy in dermatofibrosarcoma: results of a multicenter phase II study on 25 patients.

    Delphine Kérob;Raphael Porcher;Olivier Vérola;Stephane Dalle

  • Clinical and Biological Significance of CDK4 Amplification in Well-Differentiated and Dedifferentiated Liposarcomas

    Antoine Italiano;Laurence Bianchini;Elisabet Gjernes;Frédérique Keslair

  • KRAS and BRAF Mutational Status in Primary Colorectal Tumors and Related Metastatic Sites: Biological and Clinical Implications

    Antoine Italiano;Isabelle Hostein;Isabelle Soubeyran;Thibault Fabas

Frequent Co-Authors

Jean-Michel Coindre
Jean-Michel Coindre University of Bordeaux
Ola Myklebost
Ola Myklebost University of Bergen
Paul Hofman
Paul Hofman Grenoble Alpes University
Antoine Italiano
Antoine Italiano University of Bordeaux
Alain Aurias
Alain Aurias Institute Curie
Gabriella Sozzi
Gabriella Sozzi University of Milan
Céleste Lebbé
Céleste Lebbé Hôpitaux Universitaires Paris-Ouest
Raphaël Porcher
Raphaël Porcher Université Paris Cité
Azra H. Ligon
Azra H. Ligon Brigham and Women's Hospital
Cynthia C. Morton
Cynthia C. Morton Brigham and Women's Hospital

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