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Medicine

D-Index
96
Citations
64822
World Ranking
9455
National Ranking
286

Overview

Paul Hofman is affiliated with Grenoble Alpes University in France and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their primary research spans pulmonary and respiratory medicine, oncology, and cancer research, with a significant focus on molecular biology and infectious diseases.

The scientist's work concentrates on key topics including lung cancer treatments and mutations, cancer genomics and diagnostics, lung cancer diagnosis and treatment, lung cancer research studies, cancer immunotherapy and biomarkers, COVID-19 clinical research studies, and RNA modifications in cancer.

Among the notable recent papers authored or co-authored by Paul Hofman are:

  • Pulmonary pathology and COVID-19: lessons from autopsy. The experience of European Pulmonary Pathologists (2020), published in Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
  • Circulating tumour cells as a potential biomarker for lung cancer screening: a prospective cohort study (2020), published in The Lancet Respiratory Medicine
  • Genetic alterations of malignant pleural mesothelioma: association with tumor heterogeneity and overall survival (2020), published in Molecular Oncology
  • Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease (2021), published in Cell Death and Differentiation
  • Recommendations for a practical implementation of circulating tumor DNA mutation testing in metastatic non-small-cell lung cancer (2022), published in ESMO Open

Frequent collaborators with Paul Hofman include Véronique Hofman, Marius Ilié, Charles-Hugo Marquette, Jonathan Benzaquen, and Sandra Lassalle. These colleagues have co-authored numerous papers alongside Paul Hofman, highlighting ongoing research partnerships.

Paul Hofman has published extensively in several key venues, with the highest number of publications appearing in:

  • Cancers
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Translational Lung Cancer Research
  • Revue Francophone des Laboratoires
  • Journal of Thoracic Oncology

Their research output reflects a multidisciplinary approach blending clinical medicine, oncology, molecular biology, and genomics. The emphasis on lung cancer and associated diagnostics, combined with studies related to COVID-19 and infectious diseases, demonstrates the breadth and relevance of their scientific investigations.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Human polymorphism at microRNAs and microRNA target sites.

    Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang

  • Migraine as a Risk Factor for Subclinical Brain Lesions

    Mark C. Kruit;Mark A. van Buchem;Paul A. M. Hofman;Jacobus T. N. Bakkers

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

    Patrick Brest;Pierre Lapaquette;Pierre Lapaquette;Mouloud Souidi;Mouloud Souidi;Kevin Lebrigand;Kevin Lebrigand

  • Comparative study of the PD-L1 status between surgically resected specimens and matched biopsies of NSCLC patients reveal major discordances: a potential issue for anti-PD-L1 therapeutic strategies

    M. Ilie;E. Long-Mira;C. Bence;C. Butori

  • Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

    C. Allison Stewart;Elizabeth M. Park;Lixia Diao

  • Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation.

    Allison Agus;Jérémy Denizot;Jonathan Thévenot;Margarita Martinez-Medina

  • Hepatic Stem-like Phenotype and Interplay of Wnt/β-Catenin and Myc Signaling in Aggressive Childhood Liver Cancer

    Stefano Cairo;Stefano Cairo;Carolina Armengol;Carolina Armengol;Aurélien de Reyniès;Yu. Wei;Yu. Wei

  • miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity.

    M-P Puisségur;M-P Puisségur;M-P Puisségur;N M Mazure;N M Mazure;T Bertero;T Bertero;T Bertero;L Pradelli

  • "Sentinel" circulating tumor cells allow early diagnosis of lung cancer in patients with chronic obstructive pulmonary disease.

    Marius Ilie;Véronique Hofman;Elodie Long-Mira;Eric Selva

  • The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis.

    Frédéric Bost;Myriam Aouadi;Leslie Caron;Patrick Even

  • Detection of circulating tumor cells as a prognostic factor in patients undergoing radical surgery for non-small-cell lung carcinoma: comparison of the efficacy of the CellSearch Assay™ and the isolation by size of epithelial tumor cell method†

    Véronique Hofman;Marius I. Ilie;Elodie Long;Eric Selva

  • Preoperative Circulating Tumor Cell Detection Using the Isolation by Size of Epithelial Tumor Cell Method for Patients with Lung Cancer Is a New Prognostic Biomarker

    Véronique Hofman;Christelle Bonnetaud;Marius I. Ilie;Philippe Vielh

  • Surface attachment of Salmonella typhimurium to intestinal epithelia imprints the subepithelial matrix with gradients chemotactic for neutrophils.

    Beth A. McCormick;Paul M. Hofman;Jin Kim;Denice K. Carnes

  • Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy.

    Thomas Bertero;William M. Oldham;Eloise M. Grasset;Isabelle Bourget

  • Senescent cells develop a PARP-1 and nuclear factor-κB-associated secretome (PNAS)

    Mickaël Ohanna;Sandy Giuliano;Caroline Bonet;Véronique Imbert

  • Pulmonary pathology and COVID-19: lessons from autopsy. The experience of European Pulmonary Pathologists.

    Fiorella Calabrese;Federica Pezzuto;Francesco Fortarezza;Paul Hofman

Frequent Co-Authors

Bernard Mari
Bernard Mari Centre national de la recherche scientifique, CNRS
Pascal Barbry
Pascal Barbry Centre national de la recherche scientifique, CNRS
Patrick Auberger
Patrick Auberger Grenoble Alpes University
Robert Ballotti
Robert Ballotti Université Côte d'Azur
Xavier Hébuterne
Xavier Hébuterne Université Côte d'Azur
Corine Bertolotto
Corine Bertolotto Université Côte d'Azur
Julien Mazieres
Julien Mazieres Paul Sabatier University
Arlette Darfeuille-Michaud
Arlette Darfeuille-Michaud University of Clermont Auvergne
Daniel J. Klionsky
Daniel J. Klionsky University of Michigan–Ann Arbor
Fabrice Barlesi
Fabrice Barlesi Institut Gustave Roussy

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