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Microbiology

D-Index
72
Citations
14656
World Ranking
1791
National Ranking
761

Overview

Glenn W. Kaatz is affiliated with Wayne State University in the United States. Their research focuses primarily on issues related to agricultural and biological sciences as well as biochemistry, genetics, and molecular biology. The work spans several interconnected subfields, including food science, organic chemistry, toxicology, plant science, and molecular biology.

Kaatz's recent scientific output includes studies related to antimicrobial activity, bioactive compounds, and mechanisms underlying antibiotic resistance and cancer therapeutics. Notable topics covered in their research are essential oils and antimicrobial activity, synthesis and biological activity of chemical compounds, bioactive compounds and antitumor agents, plant-microbe interactions and immunity, cancer therapeutics and mechanisms, and antibiotic resistance in bacteria.

Significant publications authored or co-authored by Kaatz include:

  • Chalcones Isolated from Arrabidaea brachypoda Flowers as Inhibitors of NorA and MepA Multidrug Efflux Pumps of Staphylococcus aureus, 2020, Antibiotics
  • Modulation of the Drug Resistance by Platonia insignis Mart. Extract, Ethyl Acetate Fraction and Morelloflavone/Volkensiflavone (Biflavonoids) in Staphylococcus aureus Strains Overexpressing Efflux Pump Genes, 2020, Current Drug Metabolism

These publications indicate a focus on bacterial resistance mechanisms, particularly related to Staphylococcus aureus, and the exploration of natural compounds that affect multidrug efflux pumps.

Frequent collaborators in Kaatz's research include José de Sousa Lima Neto, José P. Siqueira-Júnior, Humberto Medeiros Barreto, Luís Mário Rezende Júnior, and Leila Maria de Sousa Andrade. These co-authors have contributed to multiple projects, reflecting ongoing partnerships in related scientific fields.

Research dissemination has taken place in journals such as Antibiotics and Current Drug Metabolism, demonstrating a focus on microbiology, pharmacology, and drug metabolism within biomedical and biological research communities.

Best Publications

  • Efflux-mediated fluoroquinolone resistance in Staphylococcus aureus.

    G W Kaatz;S M Seo;C A Ruble

  • Antibacterial and resistance modifying activity of Rosmarinus officinalis

    Moyosoluwa Oluwatuyi;Glenn W. Kaatz;Simon Gibbons

  • Fluoroquinolone resistance protein NorA of Staphylococcus aureus is a multidrug efflux transporter

    Unknown

  • Multidrug Resistance in Staphylococcus aureus Due to Overexpression of a Novel Multidrug and Toxin Extrusion (MATE) Transport Protein

    Glenn W. Kaatz;Fionnuala McAleese;Susan M. Seo

  • Inducible NorA-mediated multidrug resistance in Staphylococcus aureus.

    G W Kaatz;S M Seo

  • ACQUISITION OF CLOSTRIDIUM DIFFICILE FROM THE HOSPITAL ENVIRONMENT

    Glenn W. Kaatz;Scott D. Gitlin;Dennis R. Schaberg;Kenneth H. Wilson

  • Phenothiazines and Thioxanthenes Inhibit Multidrug Efflux Pump Activity in Staphylococcus aureus

    Glenn W. Kaatz;Varsha V. Moudgal;Susan M. Seo;Jette E. Kristiansen

  • Efflux-Related Resistance to Norfloxacin, Dyes, and Biocides in Bloodstream Isolates of Staphylococcus aureus

    Carmen E. DeMarco;Laurel A. Cushing;Emmanuel Frempong-Manso;Susan M. Seo

  • A novel inhibitor of multidrug efflux pumps in Staphylococcus aureus

    Simon Gibbons;Moyosoluwa Oluwatuyi;Glenn W. Kaatz

  • Multidrug efflux pumps of Gram-positive bacteria.

    Bryan D. Schindler;Glenn W. Kaatz

  • Emergence of Teicoplanin Resistance During Therapy of Staphylococcus aureus Endocarditis

    Glenn W. Kaatz;Susan M. Seo;Nancy J. Dorman;Stephen A. Lerner

  • Comparative In Vitro Activities and Postantibiotic Effects of the Oxazolidinone Compounds Eperezolid (PNU-100592) and Linezolid (PNU-100766) versus Vancomycin against Staphylococcus aureus, Coagulase-Negative Staphylococci, Enterococcus faecalis, and Enterococcus faecium

    Michael J. Rybak;Michael J. Rybak;Diane M. Cappelletty;Diane M. Cappelletty;Tabitha Moldovan;Jeffrey R. Aeschlimann

  • Antimicrobial Salvage Therapy for Persistent Staphylococcal Bacteremia Using Daptomycin Plus Ceftaroline

    George Sakoulas;Pamela A. Moise;Anthony M. Casapao;Poochit Nonejuie

  • Mechanisms of fluoroquinolone resistance in genetically related strains of Staphylococcus aureus.

    Glenn W. Kaatz;Susan M. Seo

  • Evidence for the Existence of a Multidrug Efflux Transporter Distinct from NorA in Staphylococcus aureus

    Glenn W. Kaatz;Susan M. Seo;Louise O'Brien;Mohammad Wahiduzzaman

  • Mechanisms of Fluoroquinolone Resistance in Staphylococcus aureus

    Glenn W. Kaatz;Susan M. Seo;Cheryl A. Ruble

  • Antibacterials and modulators of bacterial resistance from the immature cones of Chamaecyparis lawsoniana

    Eileen C.J. Smith;Elizabeth M. Williamson;Neale Wareham;Glenn W. Kaatz

  • In vitro pharmacodynamic effects of concentration, pH, and growth phase on serum bactericidal activities of daptomycin and vancomycin.

    Kenneth C. Lamp;Michael J. Rybak;Elaine M. Bailey;Glenn W. Kaatz

  • Effects of NorA inhibitors on in vitro antibacterial activities and postantibiotic effects of levofloxacin, ciprofloxacin, and norfloxacin in genetically related strains of Staphylococcus aureus

    Jeffrey R. Aeschlimann;Linda D. Dresser;Glenn W. Kaatz;Michael J. Rybak;Michael J. Rybak

  • Multidrug efflux pump overexpression in Staphylococcus aureus after single and multiple in vitro exposures to biocides and dyes

    Aurélie A. Huet;Aurélie A. Huet;Jose L. Raygada;Kabir Mendiratta;Susan M. Seo

  • The Phenolic Diterpene Totarol Inhibits Multidrug Efflux Pump Activity in Staphylococcus aureus

    Eileen C. J. Smith;Glenn W. Kaatz;Susan M. Seo;Neale Wareham

Frequent Co-Authors

Michael J. Rybak
Michael J. Rybak Wayne State University
Simon Gibbons
Simon Gibbons University of East Anglia
Brian T. Tsuji
Brian T. Tsuji University at Buffalo, State University of New York
Gabriele Cruciani
Gabriele Cruciani University of Perugia
Richard G. Brennan
Richard G. Brennan Duke University
Keith S. Kaye
Keith S. Kaye Rutgers, The State University of New Jersey
Marcus J. Zervos
Marcus J. Zervos Wayne State University
George Sakoulas
George Sakoulas University of California, San Diego
Gian Maria Rossolini
Gian Maria Rossolini University of Florence
Marina Warner
Marina Warner Public Health England

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