World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
15411
World Ranking
11235
National Ranking
774

Juro Sakai publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Juro Sakai sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 143 publications — 23rd percentile

23% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Juro Sakai D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Juro Sakai sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 61 D-Index — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Juro Sakai is affiliated with the University of Tokyo in Japan, contributing extensively to the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research encompasses several subfields, including Molecular Biology, Physiology, Epidemiology, Cancer Research, and Cell Biology.

Their work addresses key topics related to Adipose Tissue and Metabolism, RNA modifications and cancer, Adipokines, Inflammation, and Metabolic Diseases, Epigenetics and DNA Methylation, Lipid metabolism and biosynthesis, Peroxisome Proliferator-Activated Receptors, and Mitochondrial Function and Pathology.

Juro Sakai has authored various scientific papers, with recent examples illustrating diverse metabolic and molecular biology subjects:

  • "Pemafibrate, a selective PPARα modulator, prevents non-alcoholic steatohepatitis development without reducing the hepatic triglyceride content" (2020, Scientific Reports)
  • "Epitranscriptomics in metabolic disease" (2023, Nature Metabolism)
  • "Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever" (2021, eLife)
  • "Crucial role of iron in epigenetic rewriting during adipocyte differentiation mediated by JMJD1A and TET2 activity" (2023, Nucleic Acids Research)
  • "Glutamine deficiency in solid tumor cells confers resistance to ribosomal RNA synthesis inhibitors" (2022, Nature Communications)

The scientist frequently publishes in venues that include Nature Communications, SSRN Electronic Journal, Scientific Reports, Nature Metabolism, and iScience. This variety reflects a multi-disciplinary approach within biomedical research.

Collaborative work is notable in their career, with frequent co-authors including Yoshihiro Matsumura, Hiroyuki Aburatani, Tatsuhiko Kodama, Toshiya Tanaka, and Takeshi Yoneshiro.

Best Publications

  • Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome

    Toshiya Tanaka;Joji Yamamoto;Satoshi Iwasaki;Hiroshi Asaba

  • Rabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificity.

    Sadao Takahashi;Yutaka Kawarabayasi;Tsuguhiko Nakai;Juro Sakai

  • Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment.

    Juro Sakai;Elizabeth A Duncan;Robert B Rawson;Xianxin Hua

  • Complementation Cloning of S2P, a Gene Encoding a Putative Metalloprotease Required for Intramembrane Cleavage of SREBPs

    Robert B. Rawson;Nikolai G. Zelenski;Deepak Nijhawan;Jin Ye

  • Human Apolipoprotein E Receptor 2 A NOVEL LIPOPROTEIN RECEPTOR OF THE LOW DENSITY LIPOPROTEIN RECEPTOR FAMILY PREDOMINANTLY EXPRESSED IN BRAIN

    Dong Ho Kim;Hiroaki Iijima;Kaoru Goto;Juro Sakai

  • Molecular Identification of the Sterol-Regulated Luminal Protease that Cleaves SREBPs and Controls Lipid Composition of Animal Cells

    Juro Sakai;Robert B Rawson;Peter J Espenshade;Dong Cheng

  • Low-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretion

    Takahiro Fujino;Hiroshi Asaba;Man Jong Kang;Yukio Ikeda

  • Cleavage of sterol regulatory element binding proteins (SREBPs) by CPP32 during apoptosis.

    Xiaodong Wang;Nikolai G. Zelenski;Jianxin Yang;Juro Sakai

  • cDNA Cloning of Mouse and Human Cholesterol 25-Hydroxylases, Polytopic Membrane Proteins That Synthesize a Potent Oxysterol Regulator of Lipid Metabolism

    Erik G. Lund;Thomas A. Kerr;Juro Sakai;Wei Ping Li

  • Structure, chromosome location, and expression of the human very low density lipoprotein receptor gene.

    Juro Sakai;Atsushi Hoshino;Sadao Takahashi;Yukio Miura

  • Transcriptional and epigenetic control of brown and beige adipose cell fate and function

    Takeshi Inagaki;Juro Sakai;Shingo Kajimura

  • A Small Molecule That Blocks Fat Synthesis By Inhibiting the Activation of SREBP

    Shinji Kamisuki;Qian Mao;Lutfi Abu-Elheiga;Ziwei Gu

  • Identification of Complexes between the COOH-terminal Domains of Sterol Regulatory Element-binding Proteins (SREBPs) and SREBP Cleavage-Activating Protein

    Juro Sakai;Axel Nohturfft;Dong Cheng;Y. K. Ho

  • Angiopoietin-related growth factor antagonizes obesity and insulin resistance

    Yuichi Oike;Masaki Akao;Kunio Yasunaga;Toshimasa Yamauchi

  • Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein. Evidence from in vivo competition studies.

    Juro Sakai;Axel Nohturfft;Joseph L. Goldstein;Michael S. Brown

  • Regulated Cleavage of Sterol Regulatory Element Binding Proteins Requires Sequences on Both Sides of the Endoplasmic Reticulum Membrane

    Xianxin Hua;Juro Sakai;Michael S. Brown;Joseph L. Goldstein

  • The Peroxisome Proliferator-Activated Receptor γ/Retinoid X Receptor α Heterodimer Targets the Histone Modification Enzyme PR-Set7/Setd8 Gene and Regulates Adipogenesis through a Positive Feedback Loop

    Ken Ichi Wakabayashi;Masashi Okamura;Shuichi Tsutsumi;Naoko S. Nishikawa

  • Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A

    Imari Mimura;Masaomi Nangaku;Yasuharu Kanki;Shuichi Tsutsumi

  • Cleavage Site for Sterol-regulated Protease Localized to a Leu-Ser Bond in the Lumenal Loop of Sterol Regulatory Element-binding Protein-2

    Elizabeth A. Duncan;Michael S. Brown;Joseph L. Goldstein;Juro Sakai

  • COUP-TFII acts downstream of Wnt/β-catenin signal to silence PPARγ gene expression and repress adipogenesis

    Masashi Okamura;Hiromi Kudo;Ken Ichi Wakabayashi;Toshiya Tanaka

Frequent Co-Authors

Tatsuhiko Kodama
Tatsuhiko Kodama University of Tokyo
Takao Hamakubo
Takao Hamakubo Nippon Medical School
Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Makoto Naito
Makoto Naito Niigata University
Timothy F. Osborne
Timothy F. Osborne Johns Hopkins University School of Medicine
Michael S. Brown
Michael S. Brown The University of Texas Southwestern Medical Center
Joseph L. Goldstein
Joseph L. Goldstein The University of Texas Southwestern Medical Center
Masashi Yanagisawa
Masashi Yanagisawa University of Tsukuba
Shuichi Tsutsumi
Shuichi Tsutsumi University of Tokyo
Motonobu Anai
Motonobu Anai University of Tokyo

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