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D-Index & Metrics

Biology and Biochemistry

D-Index
124
Citations
43234
World Ranking
539
National Ranking
340

Medicine

D-Index
124
Citations
43155
World Ranking
3251
National Ranking
1793

Research.com Recognitions

  • 2016 - Member of the National Academy of Sciences

Overview

Stephen G. Young is affiliated with the University of California, Los Angeles in the United States. Their research spans predominantly the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Molecular Biology, Cardiology and Cardiovascular Medicine, Endocrinology, Diabetes and Metabolism, Cancer Research, and Biochemistry.

The main topics of their work include:

  • Lipid metabolism and disorders
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • RNA Research and Splicing
  • Nuclear Structure and Function
  • Lipid metabolism and biosynthesis
  • Cholesterol and Lipid Metabolism
  • Caveolin-1 and cellular processes

Stephen G. Young has published extensively in various scientific journals. The frequent publication venues include:

  • Proceedings of the National Academy of Sciences
  • Journal of Lipid Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Investigation
  • Nature Metabolism

Major papers by the scientist include:

  • High-Sensitivity Cardiac Troponin on Presentation to Rule Out Myocardial Infarction: A Stepped-Wedge Cluster Randomized Controlled Trial, 2021, Circulation
  • Acoustofluidic sonoporation for gene delivery to human hematopoietic stem and progenitor cells, 2020, Proceedings of the National Academy of Sciences
  • Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism, 2020, Proceedings of the National Academy of Sciences
  • High-resolution visualization and quantification of nucleic acid-based therapeutics in cells and tissues using Nanoscale secondary ion mass spectrometry (NanoSIMS), 2020, Nucleic Acids Research
  • Aster Proteins Regulate the Accessible Cholesterol Pool in the Plasma Membrane, 2020, Molecular and Cellular Biology

Frequent co-authors of Stephen G. Young include:

  • Loren G. Fong
  • Michael Ploug
  • Thomas A. Weston
  • Wenxin Song
  • Peter Tontonoz

In 2016, Stephen G. Young was recognized as a Member of the National Academy of Sciences.

Best Publications

  • MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B

    Jennifa Gosling;Sarah Slaymaker;Long Gu;Susan Tseng

  • Probucol inhibits oxidative modification of low density lipoprotein.

    S Parthasarathy;S G Young;J L Witztum;R C Pittman

  • The knockout mouse project

    Christopher P. Austin;James F. Battey;Allan Bradley;Maja Bucan

  • Lamins A and C but not lamin B1 regulate nuclear mechanics

    Jan Lammerding;Loren G. Fong;Julie Y. Ji;Karen Reue;Karen Reue

  • Recent progress in understanding apolipoprotein B.

    S G Young

  • ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration.

    Jin-A Lee;Anne Beigneux;S. Tariq Ahmad;Stephen G. Young

  • Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein-Binding Protein 1 Plays a Critical Role in the Lipolytic Processing of Chylomicrons

    Anne P. Beigneux;Brandon S.J. Davies;Peter Gin;Michael M. Weinstein

  • Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect.

    Martin O. Bergo;Bryant Gavino;Jed Ross;Walter K. Schmidt

  • Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice

    Martin Raabe;Murielle M. Véniant;Meghan A. Sullivan;Constance H. Zlot

  • Lamin B1 is required for mouse development and nuclear integrity.

    Laurent Vergnes;Miklós Péterfy;Martin O. Bergo;Stephen G. Young

  • Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation.

    M F Linton;R Gish;S T Hubl;E Bütler

  • Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin.

    X Z Huang;J F Wu;D Cass;D J Erle

  • Linking Lipid Metabolism to the Innate Immune Response in Macrophages through Sterol Regulatory Element Binding Protein -1a

    Seung Soon Im;Leyla Yousef;Christoph Blaschitz;Janet Z. Liu

  • A Protein Farnesyltransferase Inhibitor Ameliorates Disease in a Mouse Model of Progeria

    Loren G. Fong;David Frost;Margarita Meta;Xin Qiao

  • GPIHBP1 Is Responsible for the Entry of Lipoprotein Lipase into Capillaries

    Brandon S.J. Davies;Anne P. Beigneux;Richard H. Barnes;Yiping Tu

  • Biochemistry and pathophysiology of intravascular and intracellular lipolysis

    Stephen G. Young;Rudolf Zechner

  • Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson–Gilford progeria syndrome mutation

    Shao H. Yang;Martin O. Bergo;Julia I. Toth;Xin Qiao

  • Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes.

    Robert V. Farese;Sandra L. Ruland;Laura M. Flynn;Renee P. Stokowski

  • Knockout of the abetalipoproteinemia gene in mice: Reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes

    Martin Raabe;Laura M. Flynn;Constance H. Zlot;Jinny S. Wong

  • Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice.

    Edward Kim;Jonathan D. Lowenson;Duncan C. MacLaren;Steven Clarke

Frequent Co-Authors

Loren G. Fong
Loren G. Fong University of California, Los Angeles
Anne P. Beigneux
Anne P. Beigneux University of California, Los Angeles
Michael Ploug
Michael Ploug University of Copenhagen
André Bensadoun
André Bensadoun Cornell University
Peter Tontonoz
Peter Tontonoz University of California, Los Angeles
Karen Reue
Karen Reue University of California, Los Angeles
Linda K. Curtiss
Linda K. Curtiss Scripps Research Institute
MacRae F. Linton
MacRae F. Linton Vanderbilt University
Joseph L. Witztum
Joseph L. Witztum University of California, San Diego
Robert V. Farese
Robert V. Farese Harvard University

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