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Biology and Biochemistry

D-Index
66
Citations
13446
World Ranking
8807
National Ranking
3929

Overview

Jacques U. Baenziger is affiliated with Washington University in St. Louis in the United States. Their research focuses primarily on biochemistry, genetics, and molecular biology, with specific expertise in molecular biology, cellular and molecular neuroscience, pharmacology, genetics, and electrochemistry.

The scientist's work spans several key topics including:

  • Nicotinic Acetylcholine Receptors Study
  • Ion channel regulation and function
  • Receptor Mechanisms and Signaling
  • Lipid Membrane Structure and Behavior
  • Neuroscience and Neuropharmacology Research
  • Cholinesterase and Neurodegenerative Diseases
  • Venomous Animal Envenomation and Studies

Jacques U. Baenziger has published extensively in several scientific journals. Frequent publication venues include:

  • Biophysical Journal
  • Biophysical Reviews
  • Nature Communications
  • Nature Chemical Biology
  • Journal of Biological Chemistry

Recent papers authored or co-authored by Baenziger include:

  • "Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor," 2022, Neuron
  • "Ion channels as lipid sensors: from structures to mechanisms," 2020, Nature Chemical Biology
  • "The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors," 2022, Nature Communications
  • "Structural basis for the modulation of pentameric ligand-gated ion channel function by lipids," 2020, Biochimica et Biophysica Acta (BBA) - Biomembranes
  • "Recent Insight into Lipid Binding and Lipid Modulation of Pentameric Ligand-Gated Ion Channels," 2022, Biomolecules

Collaborations have been an integral part of Baenziger's research efforts. Frequent co-authors include:

  • Mackenzie J. Thompson
  • Hugues Nury
  • Eleftherios Zarkadas
  • Anna Ananchenko
  • François Dehez

The scientist's contributions mainly address the mechanisms underlying ion channel regulation and receptor signaling, with several works exploring nicotinic acetylcholine receptors and their interactions with ligands or toxins. Additional research has focused on lipid interactions with membrane proteins and neuropharmacology.

Best Publications

  • The asparagine-linked oligosaccharides on bovine fetuin. Structural analysis of N-glycanase-released oligosaccharides by 500-megahertz 1H NMR spectroscopy

    E D Green;G Adelt;J U Baenziger;S Wilson

  • Structure of the carbohydrate units of IgA1 immunoglobulin. II. Structure of the O-glycosidically linked oligosaccharide units.

    Jacques Baenziger;Stuart Kornfeld

  • Human platelet-derived growth factor. Purification and resolution into two active protein fractions.

    T F Deuel;J S Huang;R T Proffitt;J U Baenziger

  • Asparagine-linked oligosaccharides on lutropin, follitropin, and thyrotropin. II. Distributions of sulfated and sialylated oligosaccharides on bovine, ovine, and human pituitary glycoprotein hormones.

    E D Green;J U Baenziger

  • Pituitary glycoprotein hormone oligosaccharides: Structure, synthesis and function of the asparagine-linked oligosaccharides on lutropin, follitropin and thyrotropin

    Jacques U. Baenziger;Eric D. Green

  • A hepatic reticuloendothelial cell receptor specific for SO4-4GalNAcβ1, 4GlcNAcβ1,2Manα that mediates rapid clearance of lutropin

    Dorothy Fiete;Vandana Srivastava;Ole Hindsgaul;Jacques U. Baenziger

  • Structure of the carbohydrate units of IgA1 immunoglobulin. I. Composition, glycopeptide isolation, and structure of the asparagine-linked oligosaccharide units.

    Jacques Baenziger;Stuart Kornfeld

  • Galactose and N-acetylgalactosamine-specific endocytosis of glycopeptides by isolated rat hepatocytes

    Jacques U. Baenziger;Dorothy Fiete

  • Structure of the complex oligosaccharides of fetuin.

    Jacques Baenziger;D. Fiete

  • Human hepatic lectin. Physiochemical properties and specificity.

    Jacques Baenziger;Y. Maynard

  • The Structure of the Glycopeptide of Human γG Myeloma Proteins

    Rosalind Kornfeld;James Keller;Jacques Baenziger;Stuart Kornfeld

  • Deficient uridine diphosphate-N-acetylglucosamine:glycoprotein N-acetylglucosaminyltransferase activity in a clone of Chinese hamster ovary cells with altered surface glycoproteins.

    C Gottlieb;J Baenziger;S Kornfeld

  • A cysteine-rich domain of the ''mannose'' receptor mediates GalNAc-4-SO4 binding

    Dorothy J. Fiete;Mary C. Beranek;Jacques U. Baenziger

  • Circulatory half-life but not interaction with the lutropin/chorionic gonadotropin receptor is modulated by sulfation of bovine lutropin oligosaccharides

    Jacques U. Baenziger;Swatantar Kumar;Robbin M. Brodbeck;Peter L. Smith

  • The asialoglycoprotein receptor clears glycoconjugates terminating with sialic acidα2,6GalNAc

    Eric I. Park;Yiling Mi;Carlo Unverzagt;Hans-Joachim Gabius

  • Separation of neutral oligosaccharides by high-performance liquid chromatography.

    Scott J. Mellis;Jacques U. Baenziger

  • Structure of the Carbohydrate Units of IgE Immunoglobulin: I. OVER-ALL COMPOSITION, GLYCOPEPTIDE ISOLATION, AND STRUCTURE OF THE HIGH MANNOSE OLIGOSACCHARIDE UNIT

    Jacques Baenziger;Stuart Kornfeld;Shaul Kochwa

  • Structural elucidation of the disulfated oligosaccharide from bovine lutropin.

    E D Green;H van Halbeek;I Boime;J U Baenziger

  • Determination of plasma membrane lipid mass and composition in cultured Chinese hamster ovary cells using high gradient magnetic affinity chromatography

    D E Warnock;C Roberts;M S Lutz;W A Blackburn

  • Transport of newly synthesized glucosylceramide to the plasma membrane by a non-Golgi pathway

    Dale E. Warnock;Mallory S. Lutz;Wendy A. Blackburn;William W. Young

Frequent Co-Authors

Lora V. Hooper
Lora V. Hooper The University of Texas Southwestern Medical Center
Irving Boime
Irving Boime Washington University in St. Louis
Stuart Kornfeld
Stuart Kornfeld Washington University in St. Louis
Andreas R. Janecke
Andreas R. Janecke Innsbruck Medical University
Ole Hindsgaul
Ole Hindsgaul University of Alberta
Raymond R. Townsend
Raymond R. Townsend University of Pennsylvania
Richard D. Cummings
Richard D. Cummings Harvard Medical School
Melitta Schachner
Melitta Schachner Rutgers, The State University of New Jersey
Robert C. Piper
Robert C. Piper University of Iowa
Gerd Utermann
Gerd Utermann Innsbruck Medical University

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