Giuseppe Inesi

Overview

Best Publications

• Location of high affinity Ca 2 + -binding sites within the predicted transmembrahe domain of the sarco-plasmic reticulum Ca 2+ -ATPase

  David M. Clarke;Tip W. Loo;Giuseppe Inesi;David H. MacLennan

  700
  Citations

• Inhibition of the sarcoplasmic reticulum Ca2+ transport ATPase by thapsigargin at subnanomolar concentrations

  Y Sagara;G Inesi

  647
  Citations

• Structural basis of ion pumping by Ca2+-ATPase of the sarcoplasmic reticulum.

  Chikashi Toyoshima;Giuseppe Inesi

  545
  Citations

• Structural role of countertransport revealed in Ca(2+) pump crystal structure in the absence of Ca(2+).

  Koji Obara;Naoyuki Miyashita;Cheng Xu;Itaru Toyoshima

  304
  Citations

• Crystal structures of the calcium pump and sarcolipin in the Mg2+-bound E1 state.

  Chikashi Toyoshima;Shiho Iwasawa;Haruo Ogawa;Ayami Hirata

  299
  Citations

• Regulation of steady state filling in sarcoplasmic reticulum. Roles of back-inhibition, leakage, and slippage of the calcium pump.

  G Inesi;L de Meis

  278
  Citations

• Relationships of molecular structure and function in Ca2(+)-transport ATPase.

  G. Inesi;C. Sumbilla;M. E. Kirtley

  266
  Citations

• Thapsigargin, a high affinity and global inhibitor of intracellular Ca2+ transport ATPases.

  Giuseppe Inesi;Yutaka Sagara

  248
  Citations

• H+ countertransport and electrogenicity of the sarcoplasmic reticulum Ca2+ pump in reconstituted proteoliposomes

  Xiang Yu;S. Carroll;J.-L. Rigaud;G. Inesi

  234
  Citations

• Characterization of the inhibition of intracellular Ca2+ transport ATPases by thapsigargin.

  Y Sagara;F Fernandez-Belda;L de Meis;G Inesi

  233
  Citations

• Specific inhibitors of intracellular Ca2+ transport ATPases.

  G. Inesi;Y. Sagara

  228
  Citations

• Adenosine 5'-triphosphate dependent fluxes of manganese and and hydrogen ions in sarcoplasmic reticulum vesicles.

  Michele Chiesi;Giuseppe Inesi

  227
  Citations

• Comparative studies of cardiac and skeletal sarcoplasmic reticulum ATPases. Effect of a phospholamban antibody on enzyme activation by Ca2

  T Cantilina;Y Sagara;G Inesi;L R Jones

  220
  Citations

• Sequential mechanism of calcium binding and translocation in sarcoplasmic reticulum adenosine triphosphatase.

  G Inesi

  205
  Citations

• Use of thapsigargin to study Ca2+ homeostasis in cardiac cells.

  Terry B. Rogers;Giuseppe Inesi;Robert Wade;W. J. Lederer

  192
  Citations

• Functional consequences of glutamate, aspartate, glutamine, and asparagine mutations in the stalk sector of the Ca2+-ATPase of sarcoplasmic reticulum.

  D. M. Clarke;K. Maruyama;T. W. Loo;E. Leberer

  189
  Citations

• Thapsigargin inhibits contraction and Ca2+ transient in cardiac cells by specific inhibition of the sarcoplasmic reticulum Ca2+ pump.

  M S Kirby;Y Sagara;S Gaa;G Inesi

  177
  Citations

• Modulation of calcium binding in sarcoplasmic reticulum adenosinetriphosphatase.

  T. Watanabe;D. Lewis;R. Nakamoto;M. Kurzmack

  175
  Citations

• A conformational mechanism for formation of a dead-end complex by the sarcoplasmic reticulum ATPase with thapsigargin.

  Y Sagara;J B Wade;G Inesi

  174
  Citations

• A comparative study of calcium transients by isotopic tracer, metallochromic indicator, and intrinsic fluorescence in sarcoplasmic reticulum ATPase.

  F Fernandez-Belda;M Kurzmack;G Inesi

  173
  Citations