World's Best Scientists 2026 revealed!
Chikashi Toyoshima

Chikashi Toyoshima

D-Index & Metrics

Chemistry

D-Index
61
Citations
17077
World Ranking
9122
National Ranking
645

Chikashi Toyoshima publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Chikashi Toyoshima sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 212 publications — 37th percentile

37% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Chikashi Toyoshima D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Chikashi Toyoshima sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 61 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Research.com Recognitions

  • 2016 - Gregori Aminoff Prize, Royal Swedish Academy of Sciences for their fundamental contributions to understanding the structural basis for ATP-driven translocation of ions across membranes
  • 2005 - Member of the National Academy of Sciences

Overview

Chikashi Toyoshima is affiliated with the University of Tokyo in Japan and has contributed extensively to the fields of biochemistry, genetics, and molecular biology. Their research spans multiple subfields, including molecular biology, organic chemistry, endocrinology, diabetes and metabolism, pulmonary and respiratory medicine, and pharmacology.

The primary topics of Chikashi Toyoshima's work include:

  • Ion Transport and Channel Regulation
  • ATP Synthase and ATPases Research
  • Photosynthetic Processes and Mechanisms
  • Signaling Pathways in Disease
  • Lipid Membrane Structure and Behavior
  • Ion channel regulation and function
  • Chemical synthesis and alkaloids

Frequent publication venues for Toyoshima include:

  • Proceedings of the National Academy of Sciences
  • FEBS Letters
  • Nature Structural & Molecular Biology
  • Journal of the American Chemical Society
  • Journal of Biological Chemistry

Their recent papers illustrate a focus on ATPase enzymes and membrane protein structure. Selected publications include:

  • Binding of cardiotonic steroids to Na +,K +-ATPase in the E2P state, 2020, Proceedings of the National Academy of Sciences
  • The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes, 2021, Nature Structural & Molecular Biology
  • What ATP binding does to the Ca 2+ pump and how nonproductive phosphoryl transfer is prevented in the absence of Ca 2+, 2020, Proceedings of the National Academy of Sciences
  • Structural Determination, Total Synthesis, and Biological Activity of Iezoside, a Highly Potent Ca2+-ATPase Inhibitor from the Marine Cyanobacterium Leptochromothrix valpauliae, 2022, Journal of the American Chemical Society
  • Cryoelectron microscopy of Na +,K +-ATPase in the two E2P states with and without cardiotonic steroids, 2022, Proceedings of the National Academy of Sciences

Some frequent co-authors who have collaborated with Toyoshima include:

  • R. Kanai
  • Flemming Cornelius
  • Bente Vilsen
  • Takaharu Sakuragi
  • Masahide Kikkawa

The scientist has been recognized with awards such as the Gregori Aminoff Prize from the Royal Swedish Academy of Sciences in 2016 for contributions to understanding ATP-driven ion translocation across membranes. They were also elected as a Member of the National Academy of Sciences in 2005.

Best Publications

  • Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 Å resolution

    Chikashi Toyoshima;Masayoshi Nakasako;Masayoshi Nakasako;Hiromi Nomura;Haruo Ogawa

  • Structural changes in the calcium pump accompanying the dissociation of calcium

    Chikashi Toyoshima;Hiromi Nomura

  • Crystal structure of the sodium - potassium pump at 2.4 A resolution

    Takehiro Shinoda;Haruo Ogawa;Flemming Cornelius;Chikashi Toyoshima

  • Myosin subfragment-1 is sufficient to move actin filaments in vitro.

    Yoko Yano Toyoshima;Stephen J. Kron;Elizabeth M. McNally;Kenneth R. Niebling

  • Crystal structure of the calcium pump with a bound ATP analogue.

    Chikashi Toyoshima;Tatsuaki Mizutani

  • Lumenal gating mechanism revealed in calcium pump crystal structures with phosphate analogues

    Chikashi Toyoshima;Hiromi Nomura;Takeo Tsuda

  • Structural basis of ion pumping by Ca2+-ATPase of the sarcoplasmic reticulum.

    Chikashi Toyoshima;Giuseppe Inesi

  • Crystal structure of the sodium-potassium pump (Na+,K+-ATPase) with bound potassium and ouabain

    Haruo Ogawa;Takehiro Shinoda;Flemming Cornelius;Chikashi Toyoshima

  • Crystal structure of a Na + -bound Na + ,K + -ATPase preceding the E1P state

    Ryuta Kanai;Haruo Ogawa;Bente Vilsen;Flemming Cornelius

  • Structure of the calcium pump from sarcoplasmic reticulum at 8-Å resolution

    Peijun Zhang;Chikashi Toyoshima;Koji Yonekura;N. Michael Green

  • Ion channel of acetylcholine receptor reconstructed from images of postsynaptic membranes

    Chikashi Toyoshima;Nigel Unwin

  • How Ca2+-ATPase pumps ions across the sarcoplasmic reticulum membrane.

    Chikashi Toyoshima

  • Structural role of countertransport revealed in Ca(2+) pump crystal structure in the absence of Ca(2+).

    Koji Obara;Naoyuki Miyashita;Cheng Xu;Itaru Toyoshima

  • Three-dimensional cryo-electron microscopy of the calcium ion pump in the sarcoplasmic reticulum membrane

    Chikashi Toyoshima;Hiroyuki Sasabe;David L. Stokes

  • Crystal structures of the calcium pump and sarcolipin in the Mg2+-bound E1 state.

    Chikashi Toyoshima;Shiho Iwasawa;Haruo Ogawa;Ayami Hirata

  • Structural aspects of ion pumping by Ca2+-ATPase of sarcoplasmic reticulum

    Chikashi Toyoshima

  • Homology modeling of the cation binding sites of Na+K+-ATPase

    Haruo Ogawa;Chikashi Toyoshima

  • Electron crystallography of ultrathin 3D protein crystals: Atomic model with charges

    Koji Yonekura;Kazuyuki Kato;Mitsuo Ogasawara;Masahiro Tomita;Masahiro Tomita

  • Modeling of the inhibitory interaction of phospholamban with the Ca2+ ATPase

    Chikashi Toyoshima;Michio Asahi;Yuji Sugita;Reena Khanna

  • Contrast transfer for frozen-hydrated specimens: determination from pairs of defocused images.

    Chikashi Toyoshima;Nigel Unwin

  • Structural basis of ion pumping by Ca2+-ATPase

    Chikashi Toyoshima

  • Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state without oligomycin

    R. Kanai;H. Ogawa;B. Vilsen;F. Cornelius

Frequent Co-Authors

Yuji Sugita
Yuji Sugita RIKEN Center for Biosystems Dynamics Research
Giuseppe Inesi
Giuseppe Inesi University of Maryland, Baltimore
Bente Vilsen
Bente Vilsen Aarhus University
David A. Lewis
David A. Lewis University of Pittsburgh
Steven J. D. Karlish
Steven J. D. Karlish Weizmann Institute of Science
David H. MacLennan
David H. MacLennan University of Toronto
Tetsu Akiyama
Tetsu Akiyama University of Tokyo
Keiichi Namba
Keiichi Namba Osaka University
Shoichi Ishiura
Shoichi Ishiura University of Tokyo

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