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Neuroscience
USA
2026

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Neuroscience

D-Index
150
Citations
80901
World Ranking
148
National Ranking
96

Medicine

D-Index
151
Citations
81594
World Ranking
1124
National Ranking
646

Research.com Recognitions

  • 2026 - Research.com Neuroscience in United States Leader Award
  • 2025 - Research.com Neuroscience in United States Leader Award
  • 2007 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

David A. Lewis is affiliated with the University of Pittsburgh in the United States. Their research spans neuroscience and biochemistry, genetics and molecular biology, contributing extensively to both fields with a focus on molecular biology, cognitive neuroscience, cellular and molecular neuroscience, biological psychiatry, and genetics.

Their work covers several main topics in neuroscience and neuropharmacology research, including:

  • Neuroscience and Neuropharmacology Research
  • Tryptophan and brain disorders
  • Neural dynamics and brain function
  • Receptor Mechanisms and Signaling
  • Memory and Neural Mechanisms
  • Neurotransmitter Receptor Influence on Behavior
  • Epigenetics and DNA Methylation

David A. Lewis has coauthored numerous papers with several frequent collaborators, including:

  • Raquel E. Gur
  • Kristen Brennand
  • Schahram Akbarian
  • Jill R. Glausier
  • John H. Krystal

The primary publication venues for their research work are:

  • Biological Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Psychiatry
  • Molecular Psychiatry
  • Cerebral Cortex

Among their recent papers are:

  • Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions, 2020, Scientific Data
  • Mechanisms underlying dorsolateral prefrontal cortex contributions to cognitive dysfunction in schizophrenia, 2021, Neuropsychopharmacology
  • Transcriptional Alterations in Dorsolateral Prefrontal Cortex and Nucleus Accumbens Implicate Neuroinflammation and Synaptic Remodeling in Opioid Use Disorder, 2021, Biological Psychiatry
  • Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders, 2021, Nature Communications
  • Cognitive Dysfunction and Prefrontal Cortical Circuit Alterations in Schizophrenia: Developmental Trajectories, 2022, Biological Psychiatry

David A. Lewis is recognized as a member of the National Academy of Medicine since 2007 and is also a member of the Association of American Physicians. Their contributions primarily focus on understanding molecular and cellular mechanisms in brain function and dysfunction, with attention to neuropsychiatric disorders.

Best Publications

  • Cortical inhibitory neurons and schizophrenia

    David A. Lewis;Takanori Hashimoto;David W. Volk

  • Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia.

    Leisa A. Glantz;David A. Lewis

  • Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex

    Giorgio A. Ascoli;Lidia Alonso-Nanclares;Stewart A. Anderson;German Barrionuevo

  • Schizophrenia as a Disorder of Neurodevelopment

    David A Lewis;Pat Levitt

  • Distributed disturbances in brain structure and function in schizophrenia.

    Lewis Da

  • Gene expression elucidates functional impact of polygenic risk for schizophrenia

    Menachem Fromer;Panos Roussos;Solveig K. Sieberts;Jessica S. Johnson

  • Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia

    David A. Lewis;Allison A. Curley;Jill R. Glausier;David W. Volk

  • Image processing and analysis methods for the Adolescent Brain Cognitive Development Study.

    Donald J. Hagler;Sean N. Hatton;M. Daniela Cornejo;Carolina Makowski

  • Gene Expression Deficits in a Subclass of GABA Neurons in the Prefrontal Cortex of Subjects with Schizophrenia

    Takanori Hashimoto;David W. Volk;Stephen M. Eggan;Karoly Mirnics

  • Catching up on schizophrenia: natural history and neurobiology

    David A Lewis;Jeffrey A Lieberman

  • Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex.

    Károly Mirnics;Frank A. Middleton;Adriana Marquez;David A. Lewis

  • Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients

    Ranjan Dutta;Jennifer McDonough;Xinghua Yin;John Peterson

  • New insights into the classification and nomenclature of cortical GABAergic interneurons

    Javier DeFelipe;Pedro L. López-Cruz;Ruth Benavides-Piccione;Ruth Benavides-Piccione;Concha Bielza

  • Decreased Glutamic Acid Decarboxylase67 Messenger RNA Expression in a Subset of Prefrontal Cortical γ-Aminobutyric Acid Neurons in Subjects With Schizophrenia

    David W. Volk;Mark C. Austin;Joseph N. Pierri;Allan R. Sampson

  • Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices

    David A. Lewis;Michael J. Campbell;Robert D. Terry;John H. Morrison

  • Controlled prospective study of postpartum mood disorders: psychological, environmental, and hormonal variables.

    Michael W. O'Hara;Janet A. Schlechte;David A. Lewis;Michael W. Varner

  • Steroid-induced psychiatric syndromes: A report of 14 cases and a review of the literature

    David A. Lewis;Robert E. Smith

  • GABA Neurons and the Mechanisms of Network Oscillations: Implications for Understanding Cortical Dysfunction in Schizophrenia

    Guillermo Gonzalez-Burgos;David A. Lewis

  • Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections.

    Teresa G. Hastings;David A. Lewis;Michael J. Zigmond

  • Local circuit neurons immunoreactive for calretinin, calbindin D-28k or parvalbumin in monkey prefrontal cortex: distribution and morphology.

    Françoise Condé;Jennifer S. Lund;David M. Jacobowitz;Kenneth G. Baimbridge

Frequent Co-Authors

Guillermo Gonzalez-Burgos
Guillermo Gonzalez-Burgos University of Pittsburgh
Karoly Mirnics
Karoly Mirnics University of Nebraska Medical Center
Kenneth N. Fish
Kenneth N. Fish University of Pittsburgh
Pat Levitt
Pat Levitt University of Southern California
Etienne Sibille
Etienne Sibille University of Toronto
Giuseppe Inesi
Giuseppe Inesi University of Maryland, Baltimore
Carol A. Tamminga
Carol A. Tamminga The University of Texas Southwestern Medical Center
George C. Tseng
George C. Tseng University of Pittsburgh
John H. Morrison
John H. Morrison University of California, Davis
German Barrionuevo
German Barrionuevo University of Pittsburgh

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