Patricia A. Taylor mainly investigates Immunology, Cytotoxic T cell, Graft-versus-host disease, T cell and Antigen. The various areas that she examines in her Immunology study include Transplantation and CD40. Patricia A. Taylor focuses mostly in the field of Graft-versus-host disease, narrowing it down to matters related to Antibody and, in some cases, In vivo.
Her study of CD28 is a part of T cell. Her work deals with themes such as Molecular biology and Blockade, which intersect with Antigen. Her Bone marrow study incorporates themes from IL-2 receptor, Cytokine, Growth factor, Keratinocyte growth factor and Stem cell.
Patricia A. Taylor focuses on Immunology, Graft-versus-host disease, Bone marrow, T cell and Transplantation. Her study focuses on the intersection of Immunology and fields such as Cytotoxic T cell with connections in the field of Leukemia. Her study on Graft-versus-host disease also encompasses disciplines like
Her Bone marrow research integrates issues from Myeloid, Molecular biology and Haematopoiesis, Stem cell. Her T cell research is multidisciplinary, relying on both Receptor, Total body irradiation, Priming and Lymphocyte. Her Transplantation study integrates concerns from other disciplines, such as T lymphocyte and Histocompatibility.
Her scientific interests lie mostly in Atopic dermatitis, Immunology, T cell, Dermatology and Microbiome. She has included themes like Endotype, Stratum corneum, Pathology and Microbiology in her Atopic dermatitis study. She studies Interleukin 13, a branch of Immunology.
Her study in T cell is interdisciplinary in nature, drawing from both Proinflammatory cytokine, Inflammation and CD8. Her CD8 course of study focuses on Cytokine and Immune system and Cancer research. Her studies deal with areas such as Hematopoietic stem cell transplantation, Signal transduction and Lymphocyte as well as Graft-versus-host disease.
The scientist’s investigation covers issues in Immunology, Atopic dermatitis, Endotype, Eczema Area and Severity Index and Microbiome. Her Immunology study frequently draws connections between adjacent fields such as Cytotoxic T cell. Her Atopic dermatitis research incorporates elements of Staphylococcus epidermidis, Staphylococcus hominis, Antimicrobial, Antimicrobial peptides and Type 2 immune response.
Her Endotype research includes themes of Dermatology Life Quality Index, Transepidermal water loss, Biopsy, Severity of illness and Filaggrin. The study incorporates disciplines such as Skin biopsy, Langerhans cell, Pathology and Gene expression profiling in addition to Eczema Area and Severity Index. Her studies in Microbiome integrate themes in fields like Dermatology, Skin pathology, Case-control study and Young adult.
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The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality.
Patricia A Taylor;Christopher J Lees;Bruce R Blazar.
Cd4+Cd25+ Immune Regulatory Cells Are Required for Induction of Tolerance to Alloantigen via Costimulatory Blockade
Patricia A. Taylor;Randolph J. Noelle;Bruce R. Blazar.
Journal of Experimental Medicine (2001)
Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis
Teruaki Nakatsuji;Tiffany H. Chen;Saisindhu Narala;Kimberly A. Chun.
Science Translational Medicine (2017)
Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13.
Steven L. Highfill;Paulo C. Rodriguez;Qing Zhou;Christine A. Goetz.
L-Selectinhi but not the L-selectinlo CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection
Patricia A. Taylor;Angela Panoskaltsis-Mortari;Jessica M. Swedin;Philip J. Lucas.
In vivo blockade of CD28/CTLA4: B7/BB1 interaction with CTLA4-Ig reduces lethal murine graft-versus-host disease across the major histocompatibility complex barrier in mice
Bruce R Blazar;Patricia A. Taylor;Peter S. Linsley;Daniel A Vallera.
Blockade of Programmed Death-1 Engagement Accelerates Graft-Versus-Host Disease Lethality by an IFN-γ-Dependent Mechanism
Bruce R. Blazar;Beatriz M. Carreno;Angela Panoskaltsis-Mortari;Laura Carter.
Journal of Immunology (2003)
p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes.
Vassiliki A. Boussiotis;Gordon J. Freeman;Patricia A. Taylor;Alla Berezovskaya.
Nature Medicine (2000)
Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation
Dullei Min;Patricia A. Taylor;Angela Panoskaltsis-Mortari;Brile Chung;Brile Chung;Brile Chung.
Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease
Christian A. Wysocki;Qi Jiang;Angela Panoskaltsis-Mortari;Patricia A. Taylor.
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