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Immunology

D-Index
46
Citations
6800
World Ranking
4644
National Ranking
2090

Overview

Xue-Zhong Yu is affiliated with the Medical College of Wisconsin in the United States. Their research spans multiple areas within the biomedical sciences, focusing primarily on medicine, biochemistry, genetics, molecular biology, immunology, and microbiology.

The main fields of study for this scientist include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology
  • Immunology and Microbiology

Yu's work addresses a variety of subfields, mainly:

  • Immunology
  • Molecular Biology
  • Oncology
  • Hematology
  • Cell Biology

The scientist's research topics reflect a focus on immune system function and cancer biology. Key topics include:

  • Immune Cell Function and Interaction
  • Hematopoietic Stem Cell Transplantation
  • Sphingolipid Metabolism and Signaling
  • Endoplasmic Reticulum Stress and Disease
  • Pancreatic and Hepatic Oncology Research
  • Pancreatic function and diabetes
  • Cancer Cells and Metastasis

Yu's publication record spans multiple journals with repeated contributions to the following venues:

  • Blood
  • The Journal of Immunology
  • Cancer Research
  • Frontiers in Immunology
  • Cell Reports

Frequent coauthors collaborating with Yu include:

  • Yongxia Wu
  • Linlu Tian
  • Hee-Jin Choi
  • M. Hanief Sofi
  • Steven Schutt

Notable recent papers authored or coauthored by Yu illustrate the breadth of their research, with selected titles, publication years, and venues as follows:

  • The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis, 2023, Nature Communications
  • A single strain of Bacteroides fragilis protects gut integrity and reduces GVHD, 2021, JCI Insight
  • Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response, 2021, Cell Reports
  • RNA binding protein PCBP1 is an intracellular immune checkpoint for shaping T cell responses in cancer immunity, 2020, Science Advances
  • Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia, 2021, Journal of Clinical Investigation

Best Publications

  • T‐cell tolerance or function is determined by combinatorial costimulatory signals

    Roza Nurieva;Sunil Thomas;Thang Nguyen;Natalia Martin-Orozco

  • CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

    Shilpak Chatterjee;Anusara Daenthanasanmak;Paramita Chakraborty;Megan W. Wyatt

  • NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis.

    Sha Yan;Zhenyao Xu;Fangzhou Lou;Lingyun Zhang

  • Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice

    Yu Yu;Dapeng Wang;Chen Liu;Kane Kaosaard

  • Non-Fc receptor-binding humanized anti-CD3 antibodies induce apoptosis of activated human T cells.

    Paul A. Carpenter;Sandra Pavlovic;J. Y. Tso;Oliver W. Press;Oliver W. Press

  • CD28 Controls Differentiation of Regulatory T Cells from Naive CD4 T Cells

    Fei Guo;Cristina Iclozan;Woong-Kyung Suh;Claudio Anasetti

  • Ex vivo expansion of human Tregs specific for alloantigens presented directly or indirectly

    Anandharaman Veerapathran;Joseph Pidala;Francisca Beato;Xue-Zhong Yu

  • CD28-Specific Antibody Prevents Graft-Versus-Host Disease in Mice

    Xue Zhong Yu;Sasha J. Bidwell;Paul J. Martin;Paul J. Martin;Claudio Anasetti;Claudio Anasetti

  • T helper17 cells are sufficient but not necessary to induce acute graft-versus-host disease.

    Cristina Iclozan;Yu Yu;Chen Liu;Yaming Liang

  • Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation

    Hung D. Nguyen;Shilpak Chatterjee;Kelley M.K. Haarberg;Yongxia Wu

  • Antigen‐dependent suppression of alloresponses by Foxp3‐induced regulatory T cells in transplantation

    Michael H. Albert;Michael H. Albert;Yan Liu;Claudio Anasetti;Claudio Anasetti;Xue-Zhong Yu;Xue-Zhong Yu

  • PKCθ is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice

    Javier O. Valenzuela;Cristina Iclozan;Mohammad S. Hossain;Martin Prlic

  • Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling

    Kenrick Semple;Antony Nguyen;Yu Yu;Honglin Wang

  • Role of CD28 in Acute Graft-Versus-Host Disease

    Xue Zhong Yu;Paul J. Martin;Claudio Anasetti

  • CD28 ligation induces transplantation tolerance by IFN-γ–dependent depletion of T cells that recognize alloantigens

    Xue-Zhong Yu;Michael H. Albert;Paul J. Martin;Claudio Anasetti

  • Inhibition of BTK and ITK with Ibrutinib Is Effective in the Prevention of Chronic Graft-versus-Host Disease in Mice

    Steven D. Schutt;Jianing Fu;Jianing Fu;Hung Nguyen;David Bastian

  • MicroRNA-31 negatively regulates peripherally derived regulatory T-cell generation by repressing retinoic acid-inducible protein 3

    Lingyun Zhang;Fang Ke;Zhaoyuan Liu;Jing Bai

  • Advances in transplantation tolerance.

    Xue-Zhong Yu;Paul Carpenter;Claudio Anasetti

  • Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity.

    Paramita Chakraborty;Silvia G. Vaena;Krishnamurthy Thyagarajan;Shilpak Chatterjee

  • TGF-β–dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis

    Honglin Wang;Thorsten Peters;Anca Sindrilaru;Daniel Kess

  • Role of mitogen-activated protein kinases in activation-induced apoptosis of T cells

    L Zhu;X Yu;Y Akatsuka;J A Cooper

Frequent Co-Authors

Claudio Anasetti
Claudio Anasetti Fred Hutchinson Cancer Research Center
Chen Liu
Chen Liu Yale University
Paul J. Martin
Paul J. Martin Fred Hutchinson Cancer Research Center
Amer A. Beg
Amer A. Beg University of South Florida
Andrew S. Kraft
Andrew S. Kraft University of Arizona
Besim Ogretmen
Besim Ogretmen Medical University of South Carolina
Bruce R. Blazar
Bruce R. Blazar University of Minnesota
Chrystal M. Paulos
Chrystal M. Paulos Emory University
Chen Dong
Chen Dong Tsinghua University
Stephen Tomlinson
Stephen Tomlinson Medical University of South Carolina

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