D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 59 Citations 12,954 179 World Ranking 8321 National Ranking 3769

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Apoptosis

His primary areas of investigation include Cell biology, Protein kinase A, Molecular biology, Apoptosis and Cancer research. The Protein kinase A study combines topics in areas such as Protein phosphatase 2 and Signal transduction, Kinase activity. The concepts of his Kinase activity study are interwoven with issues in PRKCQ and Phorbol, Protein kinase C.

His research in Molecular biology intersects with topics in p38 mitogen-activated protein kinases, MAPK/ERK pathway, MAPK phosphatase, Tyrosine phosphorylation and GRB2. His studies in Cancer research integrate themes in fields like Muscle hypertrophy, Protein kinase B, P70-S6 Kinase 1 and Angiotensin receptor. His research in Proteasome inhibitor focuses on subjects like Cancer cell, which are connected to Transfection.

His most cited work include:

  • Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane. (1179 citations)
  • Phase II Study of Sorafenib in Patients With Metastatic or Recurrent Sarcomas (413 citations)
  • Conditional Expression of the Mitogen-activated Protein Kinase (MAPK) Phosphatase MKP-1 Preferentially Inhibits p38 MAPK and Stress-activated Protein Kinase in U937 Cells (410 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cancer research, Kinase, Cell biology, Protein kinase A and Molecular biology. His Cancer research research incorporates elements of Cancer cell, Cancer, Prostate cancer, PIM1 and Signal transduction. His Kinase study combines topics from a wide range of disciplines, such as mTORC1, PI3K/AKT/mTOR pathway, T cell, Immunology and Phosphorylation.

His research integrates issues of Cyclin-dependent kinase 1, Interleukin 3 and Cell growth in his study of Cell biology. His research on Protein kinase A frequently connects to adjacent areas such as Kinase activity. His Molecular biology study integrates concerns from other disciplines, such as Phorbol, Transcription, Cellular differentiation and c-jun.

He most often published in these fields:

  • Cancer research (37.78%)
  • Kinase (31.11%)
  • Cell biology (28.89%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cancer research (37.78%)
  • Kinase (31.11%)
  • PIM1 (12.22%)

In recent papers he was focusing on the following fields of study:

Andrew S. Kraft focuses on Cancer research, Kinase, PIM1, Cell biology and Prostate cancer. His biological study spans a wide range of topics, including Cancer cell, Cancer, T cell, Immunology and Signal transduction. His Kinase research is mostly focused on the topic Protein kinase A.

The various areas that he examines in his Protein kinase A study include Mitochondrion, Endocrinology, Knockout mouse and Senescence. His PIM1 research is multidisciplinary, incorporating perspectives in Haematopoiesis, Stem cell, Ponatinib, Tyrosine-kinase inhibitor and Leukemia. His work on Effector as part of general Cell biology study is frequently linked to IRS1, therefore connecting diverse disciplines of science.

Between 2012 and 2021, his most popular works were:

  • Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial (133 citations)
  • The 2014 Surgeon General's report: “The Health Consequences of Smoking–50 Years of Progress”: A paradigm shift in cancer care (128 citations)
  • PIM kinase (and Akt) biology and signaling in tumors. (93 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Apoptosis

Kinase, Cancer research, Cell biology, Internal medicine and Cell growth are his primary areas of study. In his research on the topic of Kinase, Endocrinology, Knockout mouse and Mitochondrion is strongly related with Cell aging. Andrew S. Kraft interconnects Protein kinase A, mTORC1, PIM1 and Signal transduction, Kinase activity in the investigation of issues within Cancer research.

As part of his studies on Cell biology, Andrew S. Kraft often connects relevant areas like T cell. His work deals with themes such as Gastroenterology, Sarcoma and Oncology, which intersect with Internal medicine. Andrew S. Kraft has researched Reactive oxygen species in several fields, including Tumor microenvironment, Cancer cell and Molecular biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane.

Andrew S. Kraft;Wayne B. Anderson.
Nature (1983)

1961 Citations

Conditional Expression of the Mitogen-activated Protein Kinase (MAPK) Phosphatase MKP-1 Preferentially Inhibits p38 MAPK and Stress-activated Protein Kinase in U937 Cells

Christopher C. Franklin;Andrew S. Kraft.
Journal of Biological Chemistry (1997)

635 Citations

Phase II Study of Sorafenib in Patients With Metastatic or Recurrent Sarcomas

Robert G. Maki;David R. D'Adamo;Mary L. Keohan;Michael Saulle.
Journal of Clinical Oncology (2009)

600 Citations

Elevated Akt Activity Protects the Prostate Cancer Cell Line LNCaP from TRAIL-induced Apoptosis

Alexandre Nesterov;Xiaojun Lu;Michael Johnson;Gary J. Miller.
Journal of Biological Chemistry (2001)

384 Citations

Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60

Andrew S. Kraft;Jeffrey B. Smith;Roger L. Berkow.
Proceedings of the National Academy of Sciences of the United States of America (1986)

348 Citations

The PIM-2 Kinase Phosphorylates BAD on Serine 112 and Reverses BAD-induced Cell Death

Bin Yan;Marina Zemskova;Sheldon Holder;Vernon Chin.
Journal of Biological Chemistry (2003)

325 Citations

The Role of the Transcription Factor Sp1 in Regulating the Expression of the WAF1/CIP1 Gene in U937 Leukemic Cells

Joseph R. Biggs;Jeffery E. Kudlow;Andrew S. Kraft.
Journal of Biological Chemistry (1996)

256 Citations

The 2014 Surgeon General's report: “The Health Consequences of Smoking–50 Years of Progress”: A paradigm shift in cancer care

Graham W. Warren;Anthony J. Alberg;Andrew S. Kraft;K. Michael Cummings.
Cancer (2014)

253 Citations

The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells.

Thomas R. Johnson;Kimberley Stone;Malti Nikrad;Tammie Yeh.
Oncogene (2003)

250 Citations

Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor

Stuart J. Frank;Stuart J. Frank;Woelsung Yi;Yanming Zhao;Jeffrey F. Goldsmith.
Journal of Biological Chemistry (1995)

250 Citations

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