D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 73 Citations 15,594 298 World Ranking 1272 National Ranking 646

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

His primary scientific interests are in Neuroscience, Protein kinase C, Hippocampus, Cell biology and Hippocampal formation. His research investigates the connection with Neuroscience and areas like Signal transduction which intersect with concerns in Gene expression. He interconnects Endocrinology, Neurodegeneration, Internal medicine and Amyloid in the investigation of issues within Protein kinase C.

Daniel L. Alkon combines subjects such as Gene, Postsynaptic potential and Bioinformatics with his study of Hippocampus. His studies deal with areas such as Regulation of gene expression and Messenger RNA, RNA-binding protein, Untranslated region as well as Cell biology. Many of his research projects under Hippocampal formation are closely connected to Eyelid Conditioning with Eyelid Conditioning, tying the diverse disciplines of science together.

His most cited work include:

  • Accelerating the convergence of the back-propagation method (892 citations)
  • Brain Insulin Receptors and Spatial Memory CORRELATED CHANGES IN GENE EXPRESSION, TYROSINE PHOSPHORYLATION, AND SIGNALING MOLECULES IN THE HIPPOCAMPUS OF WATER MAZE TRAINED RATS (461 citations)
  • Insulin and the insulin receptor in experimental models of learning and memory (360 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Neuroscience, Protein kinase C, Cell biology, Associative learning and Hermissenda. His Hippocampal formation and Hippocampus study, which is part of a larger body of work in Neuroscience, is frequently linked to Classical conditioning, bridging the gap between disciplines. His research integrates issues of Activator, Protein kinase A and Pharmacology in his study of Protein kinase C.

He has included themes like Downregulation and upregulation and Neuron in his Cell biology study. The various areas that Daniel L. Alkon examines in his Associative learning study include Artificial neural network, Content-addressable memory and Artificial intelligence. While the research belongs to areas of Biophysics, Daniel L. Alkon spends his time largely on the problem of Calcium, intersecting his research to questions surrounding Endocrinology.

He most often published in these fields:

  • Neuroscience (36.29%)
  • Protein kinase C (24.93%)
  • Cell biology (17.45%)

What were the highlights of his more recent work (between 2008-2020)?

  • Protein kinase C (24.93%)
  • Neuroscience (36.29%)
  • Disease (10.53%)

In recent papers he was focusing on the following fields of study:

Daniel L. Alkon mainly investigates Protein kinase C, Neuroscience, Disease, Bryostatin and Activator. His Protein kinase C study is related to the wider topic of Kinase. His study in Neuroscience focuses on Synaptogenesis in particular.

His work deals with themes such as Enzyme activator, Internal medicine, Inhibitory postsynaptic potential and Protein Kinase C-epsilon, which intersect with Bryostatin. His Neurotrophic factors study incorporates themes from Hippocampal formation and Endocrinology. In the field of Cell biology, his study on Protein kinase A overlaps with subjects such as LRP1.

Between 2008 and 2020, his most popular works were:

  • PKC ε Activation Prevents Synaptic Loss, Aβ Elevation, and Cognitive Deficits in Alzheimer's Disease Transgenic Mice (156 citations)
  • Protein synthesis required for long-term memory is induced by PKC activation on days preceding associative learning (101 citations)
  • ApoE4 and Aβ Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation (72 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His primary areas of study are Protein kinase C, Neuroscience, Bryostatin, Neurotrophic factors and Bryostatin 1. His work carried out in the field of Protein kinase C brings together such families of science as Activator, Long-term memory, Neurodegeneration and Pharmacology. His research investigates the link between Activator and topics such as Endocrinology that cross with problems in Internal medicine and Synapse.

His work on Synaptogenesis as part of general Neuroscience research is frequently linked to Synaptophysin, bridging the gap between disciplines. His Neurotrophic factors study integrates concerns from other disciplines, such as Hippocampal formation and Vascular disease. His Bryostatin 1 research is multidisciplinary, relying on both Expanded access, Molecular biology, Dementia and Neuroprotection.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Accelerating the convergence of the back-propagation method

T. P. Vogl;J. K. Mangis;A. K. Rigler;W. T. Zink.
Biological Cybernetics (1988)

1418 Citations

Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats.

Weiqin Zhao;Hui Chen;Hui Xu;Elizabeth Moore.
Journal of Biological Chemistry (1999)

635 Citations

Insulin and the insulin receptor in experimental models of learning and memory

Wei-Qin Zhao;Hui Chen;Michael J. Quon;Daniel L. Alkon.
European Journal of Pharmacology (2004)

552 Citations

Calcium-mediated reduction of ionic currents: a biophysical memory trace.

Daniel L. Alkon.
Science (1984)

545 Citations

A spatial-temporal model of cell activation.

Daniel L. Alkon;Howard Rasmussen.
Science (1988)

470 Citations

Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice.

René Etcheberrigaray;Mathew Tan;Ilse Dewachter;Cuno Kuipéri.
Proceedings of the National Academy of Sciences of the United States of America (2004)

450 Citations

Internal Ca2+ mobilization is altered in fibroblasts from patients with Alzheimer disease.

Etsuro Ito;Kotaro Oka;René Etcheberrigaray;Thomas J. Nelson.
Proceedings of the National Academy of Sciences of the United States of America (1994)

410 Citations

Conditioning-specific membrane changes of rabbit hippocampal neurons measured in vitro

John F. Disterhoft;Douglas A. Coulter;Daniel L. Alkon.
Proceedings of the National Academy of Sciences of the United States of America (1986)

392 Citations

Imaging of memory-specific changes in the distribution of protein kinase C in the hippocampus

James L. Olds;Matthew L. Anderson;Donna L. McPhie;Latonia D. Staten.
Science (1989)

310 Citations

PKC signaling deficits: a mechanistic hypothesis for the origins of Alzheimer's disease.

Daniel L. Alkon;Miao-Kun Sun;Thomas J. Nelson.
Trends in Pharmacological Sciences (2007)

299 Citations

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