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Neuroscience

D-Index
88
Citations
27077
World Ranking
1216
National Ranking
621

Research.com Recognitions

  • 1992 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

John F. Disterhoft is affiliated with Northwestern University in the United States and has contributed extensively to the field of neuroscience. Their research spans several subfields, including cognitive neuroscience, cellular and molecular neuroscience, neurology, physiology, and sensory systems. The primary focus areas include neuroscience and neuropharmacology research, memory and neural mechanisms, neural dynamics and brain function, neuroinflammation and neurodegeneration mechanisms, Alzheimer's disease research and treatments, olfactory and sensory function studies, and functional brain connectivity studies.

The scientist has published numerous works in well-known venues, with frequent publications appearing in Neurobiology of Aging, bioRxiv (Cold Spring Harbor Laboratory), Neurobiology of Learning and Memory, eNeuro, and Hippocampus.

Recent papers by John F. Disterhoft demonstrate diverse investigations into neuronal function and aging. These include:

  • Intrinsic Excitability Increase in Cerebellar Purkinje Cells after Delay Eye-Blink Conditioning in Mice, 2020, Journal of Neuroscience
  • Cognitive aging is associated with redistribution of synaptic weights in the hippocampus, 2021, Proceedings of the National Academy of Sciences
  • Persistent firing in LEC III neurons is differentially modulated by learning and aging, 2020, eLife
  • The TgF344-AD rat: behavioral and proteomic changes associated with aging and protein expression in a transgenic rat model of Alzheimer's disease, 2022, Neurobiology of Aging
  • Variability in sub-threshold signaling linked to Alzheimer's disease emerges with age and amyloid plaque deposition in mouse ventral CA1 pyramidal neurons, 2021, Neurobiology of Aging

Collaboration has been an important aspect of their work, with frequent co-authors including Craig Weiss, M. Matthew Oh, Joel L. Voss, Alik S. Widge, and Nicola Bertolino. These collaborations likely support interdisciplinary approaches within neuroscience and related fields.

John F. Disterhoft's contributions have been recognized through honors such as being named a Fellow of the American Association for the Advancement of Science (AAAS) in 1992.

Best Publications

  • Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

    Holly Oakley;Sarah L. Cole;Sreemathi Logan;Erika Maus

  • Hippocampectomy disrupts trace eye-blink conditioning in rabbits.

    James R. Moyer;Richard A. Deyo;John F. Disterhoft

  • BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease

    Masuo Ohno;Evgeny A Sametsky;Linda H Younkin;Holly Oakley

  • Learning Centers of Rat Brain Mapped by Measuring Latencies of Conditioned Unit Responses

    James Olds;John F. Disterhoft;Menahem Segal;Carol L. Kornblith

  • Trace Eyeblink Conditioning Increases CA1 Excitability in a Transient and Learning-Specific Manner

    James R. Moyer;Lucien T. Thompson;John F. Disterhoft

  • Hippocampectomy disrupts auditory trace fear conditioning and contextual fear conditioning in the rat.

    Matthew D. McEchron;Hans Bouwmeester;Wilbur Tseng;Craig Weiss

  • Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry

    Allison M Bond;Michael J W VanGompel;Michael J W VanGompel;Evgeny A Sametsky;Mary F Clark

  • Conditioning-specific membrane changes of rabbit hippocampal neurons measured in vitro

    John F. Disterhoft;Douglas A. Coulter;Daniel L. Alkon

  • Hippocampal lesions prevent trace eyeblink conditioning in the freely moving rat

    Craig Weiss;Hans Bouwmeester;John M Power;John F Disterhoft

  • BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice

    Masuo Ohno;Sarah L. Cole;Marina Yasvoina;Jie Zhao

  • Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age- and concentration-dependent manner.

    J. R. Moyer;L. T. Thompson;J. P. Black;J. F. Disterhoft

  • Nimodipine facilitates associative learning in aging rabbits

    Richard A. Deyo;Karen T. Straube;John F. Disterhoft

  • Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.

    Masuo Ohno;Lei Chang;Wilbur Tseng;Holly Oakley

  • Transient Changes in Excitability of Rabbit CA3 Neurons With a Time Course Appropriate to Support Memory Consolidation

    L. T. Thompson;J. R. Moyer;J. F. Disterhoft

  • Sequence of Single Neuron Changes in CA1 Hippocampus of Rabbits During Acquisition of Trace Eyeblink Conditioned Responses

    Matthew D. McEchron;John F. Disterhoft

  • Associative learning elicits the formation of multiple-synapse boutons

    Y Geinisman;R W Berry;J F Disterhoft;J M Power

  • Hippocampus-dependent learning facilitated by a monoclonal antibody or D-cycloserine

    Lucien T. Thompson;Joseph R. Moskal;John F. Disterhoft

  • Intact delay-eyeblink classical conditioning in amnesia.

    John D. E. Gabrieli;Regina McGlinchey-Berroth;Regina McGlinchey-Berroth;Maria C. Carrillo;Mark A. Gluck

  • Impaired trace eyeblink conditioning in bilateral, medial-temporal lobe amnesia.

    Regina McGlinchey-Berroth;Maria C. Carrillo;John D. E. Gabrieli;Catherine M. Brawn

  • Lesions of the caudal area of rabbit medial prefrontal cortex impair trace eyeblink conditioning

    Michelle A. Kronforst-Collins;John F. Disterhoft

  • Learning and memory

    Daniel L. Alkon;David G. Amaral;Mark F. Bear;Joel Black

Frequent Co-Authors

Craig Weiss
Craig Weiss Northwestern University
Masuo Ohno
Masuo Ohno Nathan Kline Institute for Psychiatric Research
Joseph R. Moskal
Joseph R. Moskal Northwestern University
Jeffrey Burgdorf
Jeffrey Burgdorf Northwestern University
Douglas A. Coulter
Douglas A. Coulter Children's Hospital of Philadelphia
Patric K. Stanton
Patric K. Stanton New York Medical College
Regina E. McGlinchey
Regina E. McGlinchey Boston University
Laird S. Cermak
Laird S. Cermak Boston University
Daniel L. Alkon
Daniel L. Alkon West Virginia University

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