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Molecular Biology

D-Index
67
Citations
30458
World Ranking
1543
National Ranking
20

Medicine

D-Index
72
Citations
33574
World Ranking
19750
National Ranking
247

Overview

Miriam Cnop is a researcher affiliated with the Université Libre de Bruxelles in Belgium. Their academic work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on molecular and cellular mechanisms relevant to human health and disease.

The scientist's research covers several subfields including Surgery, Molecular Biology, Genetics, Endocrinology, Diabetes and Metabolism, and Cell Biology. Their scholarly contributions are concentrated around key topics such as pancreatic function and diabetes, diabetes and associated disorders, endoplasmic reticulum stress and disease, diet and metabolism studies, diabetes management and research, metabolism related to diabetes and cancer, and gut microbiota and health.

Some notable recent publications by Miriam Cnop include:

  • "Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure," published in 2020 in Nature Reviews Endocrinology
  • "Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients," published in 2020 in Gut
  • "Link between gut microbiota and health outcomes in inulin-treated obese patients: Lessons from the Food4Gut multicenter randomized placebo-controlled trial," published in 2020 in Clinical Nutrition
  • "Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes," published in 2020 in Cell Reports
  • "Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells," published in 2020 in Stem Cell Research & Therapy

Miriam Cnop has collaborated extensively with other researchers. Frequent co-authors include:

  • Décio L. Eizirik
  • Piero Marchetti
  • Lorella Marselli
  • Anthony Piron
  • Xiaoyan Yi

Their work is disseminated across multiple publication venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Diabetologia
  • Diabetes
  • NAR Genomics and Bioinformatics
  • Endocrine Abstracts

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Free Fatty Acids and Cytokines Induce Pancreatic β-Cell Apoptosis by Different Mechanisms: Role of Nuclear Factor-κB and Endoplasmic Reticulum Stress

    Ilham Kharroubi;Laurence Ladrière;Alessandra K Cardozo;Zeynep Dogusan

  • Endoplasmic reticulum stress, obesity and diabetes

    Miriam Cnop;Miriam Cnop;Fabienne Foufelle;Licio A. Velloso

  • Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

    Daniel A. Cunha;Paul Hekerman;Laurence Ladrière;Angie Bazarra-Castro

  • Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure.

    Décio L Eizirik;Décio L Eizirik;Lorenzo Pasquali;Lorenzo Pasquali;Miriam Cnop

  • The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines.

    Décio L. Eizirik;Michael Sammeth;Thomas Bouckenooghe;Guy Bottu

  • DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients.

    Michael Volkmar;Sarah Dedeurwaerder;Daniel A Cunha;Matladi N Ndlovu

  • Selective Inhibition of Eukaryotic Translation Initiation Factor 2α Dephosphorylation Potentiates Fatty Acid-induced Endoplasmic Reticulum Stress and Causes Pancreatic β-Cell Dysfunction and Apoptosis

    Miriam Cnop;Miriam Cnop;Laurence Ladriere;Paul Hekerman;Fernanda Ortis

  • Expression of adiponectin receptors in pancreatic beta cells.

    Ilham Kharroubi;Joanne Rasschaert;Décio L Eizirik;Miriam Cnop

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • RNA-sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate

    Miriam Cnop;Baroj Abdulkarim;Guy Bottu;Daniel A. Cunha

  • The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation

    M. Cnop;S. J. Hughes;M. Igoillo-Esteve;M. B. Hoppa

  • Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells

    Miriam Cnop;Sanna Toivonen;Mariana Igoillo-Esteve;Paraskevi Salpea

  • Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB

    Daniel A. Cunha;Laurence Ladrière;Fernanda Ortis;Mariana Igoillo-Esteve

  • ER Stress in Pancreatic β Cells: The Thin Red Line Between Adaptation and Failure

    Decio L. Eizirik;Miriam Cnop;Miriam Cnop

  • Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis.

    Katleen Lemaire;Rodrigo F. Moura;Mikaela Granvik;Mariana Igoillo-Esteve;Mariana Igoillo-Esteve

  • A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis

    Karianne Fjeld;Frank Ulrich Weiss;Denise Lasher;Jonas Rosendahl

  • Causes and cures for endoplasmic reticulum stress in lipotoxic β-cell dysfunction.

    M. Cnop;L. Ladrière;M. Igoillo-Esteve;R. F. Moura

  • PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis

    Fabrice Moore;Maikel Luis Colli;Miriam Cnop;Mariana Igoillo Esteve

Frequent Co-Authors

Decio L. Eizirik
Decio L. Eizirik Université Libre de Bruxelles
Piero Marchetti
Piero Marchetti University of Pisa
Nathalie M. Delzenne
Nathalie M. Delzenne Université Catholique de Louvain
Anders Molven
Anders Molven University of Bergen
Pål R. Njølstad
Pål R. Njølstad University of Bergen
Andrew T. Hattersley
Andrew T. Hattersley University of Exeter
Leif Groop
Leif Groop Lund University
Steven E. Kahn
Steven E. Kahn University of Washington

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