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Biology and Biochemistry

D-Index
68
Citations
14407
World Ranking
7906
National Ranking
608

Overview

Noel G. Morgan is affiliated with the University of Exeter in the United Kingdom and has contributed extensively to research in medicine, particularly in the fields of biochemistry, genetics, and molecular biology. Their work primarily focuses on pancreatic function and diabetes, encompassing diabetes management and research, immune cell function and interaction, as well as aspects of viral infections and immunology.

The scientist has published studies in multiple venues, frequently contributing to bioRxiv (Cold Spring Harbor Laboratory), Diabetologia, and Diabetes. Other outlets include Frontiers in Endocrinology and Nature Reviews Endocrinology.

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Diabetologia
  • Diabetes
  • Frontiers in Endocrinology
  • Nature Reviews Endocrinology

Some of the recent papers include:

  • Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis, 2020, Diabetologia
  • An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells, 2020, Nature Communications
  • Heterogeneity and endotypes in type 1 diabetes mellitus, 2023, Nature Reviews Endocrinology
  • Non-coding variants disrupting a tissue-specific regulatory element in HK1 cause congenital hyperinsulinism, 2022, Nature Genetics
  • Altered β-Cell Prohormone Processing and Secretion in Type 1 Diabetes, 2021, Diabetes

The main topics of research addressed by Morgan cover:

  • Pancreatic function and diabetes
  • Diabetes and associated disorders
  • Diabetes Management and Research
  • Immune Cell Function and Interaction
  • Viral Infections and Immunology Research
  • Viral gastroenteritis research and epidemiology
  • Metabolism, Diabetes, and Cancer

Frequent co-authors collaborating with Noel G. Morgan include:

  • Sarah J. Richardson
  • Pia Leete
  • Mark A. Russell
  • Christine S. Flaxman
  • Knut Dahl-Jørgensen

Their research spans important subfields such as genetics, surgery, endocrinology, diabetes and metabolism, immunology, and molecular biology. This multidisciplinary approach supports investigations into complex mechanisms underlying type 1 diabetes and related metabolic disorders.

Best Publications

  • Analysis of islet inflammation in human type 1 diabetes.

    A. Willcox;S. J. Richardson;A. J. Bone;A. K. Foulis

  • Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease

    Sarah E Flanagan;Emma Haapaniemi;Mark A Russell;Richard Caswell

  • The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes.

    Sarah J. Richardson;A Willcox;AJ Bone;Alan K. Foulis

  • Detection of a Low-Grade Enteroviral Infection in the Islets of Langerhans of Living Patients Newly Diagnosed With Type 1 Diabetes

    Lars Krogvold;Bjørn Edwin;Bjørn Edwin;Trond Buanes;Trond Buanes;Gun Frisk

  • 'Seeing through a glass darkly': casting light on imidazoline 'I' sites.

    Richard M. Eglen;Alan L. Hudson;David A. Kendall;David J. Nutt

  • Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes.

    Manuela Battaglia;Simi Ahmed;Mark S. Anderson;Mark A. Atkinson

  • Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes

    Sarah J. Richardson;Teresa Rodriguez-Calvo;Ivan C. Gerling;Clayton E. Mathews

  • Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes

    Pia Leete;Abby Willcox;Lars Krogvold;Knut Dahl-Jørgensen

  • Islet-associated macrophages in type 2 diabetes

    S.J. Richardson;A. Willcox;Adrian Bone;A.K. Foulis

  • Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes

    Sefina Arif;Pia Leete;Vy Thuy Nguyen;Katherine Marks

  • Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes

    Ihsane Marhfour;Xavier Moles Lopez;Dionysios Lefkaditis;Isabelle Salmon

  • Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis

    Intza Garin;Emma L. Edghill;Ildem Akerman;Oscar Rubio-Cabezas

  • The diagnosis of insulitis in human type 1 diabetes

    M. L. Campbell-Thompson;M. A. Atkinson;A. E. Butler;N. M. Chapman

  • Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes

    Federica Vecchio;Nicola Lo Buono;Angela Stabilini;Laura Nigi

  • Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1beta and Fas ligation.

    A. C. Loweth;G. T. Williams;R. F. L. James;J. H. B. Scarpello

  • Life and death decisions of the pancreatic β-cell: the role of fatty acids

    Philip Newsholme;Deirdre Keane;Hannah J. Welters;Noel G. Morgan

  • Age-related changes in the control of hepatic cyclic AMP levels by alpha 1- and beta 2-adrenergic receptors in male rats.

    N G Morgan;P F Blackmore;J H Exton

  • Isomers of the TCF1 gene encoding hepatocyte nuclear factor-1 alpha show differential expression in the pancreas and define the relationship between mutation position and clinical phenotype in monogenic diabetes.

    Lorna W. Harries;Sian Ellard;Amanda Stride;Noel G. Morgan

  • PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction.

    Maikel Luis Colli;Jessica L E Hill;Laura Marroquí;Jessica Chaffey

  • Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1

    Sefina Arif;Pia Leete;Vy Nguyen;Katherine Marks

Frequent Co-Authors

Heikki Hyöty
Heikki Hyöty Tampere University
Alberto Pugliese
Alberto Pugliese University of Miami
Mark Peakman
Mark Peakman King's College London
John H. Exton
John H. Exton Vanderbilt University
Andrew T. Hattersley
Andrew T. Hattersley University of Exeter
Decio L. Eizirik
Decio L. Eizirik Université Libre de Bruxelles
Gwyn T. Williams
Gwyn T. Williams Keele University
Mark A. Atkinson
Mark A. Atkinson University of Florida
Thomas Mandrup-Poulsen
Thomas Mandrup-Poulsen University of Copenhagen
John A. Todd
John A. Todd University of Oxford

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