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Biology and Biochemistry

D-Index
51
Citations
11303
World Ranking
17048
National Ranking
7026

Overview

Alberto Pugliese is affiliated with the University of Miami in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on subfields such as Genetics, Surgery, Endocrinology, Diabetes and Metabolism, Immunology, and Infectious Diseases.

The scientist's work centers on several key topics, including:

  • Diabetes and associated disorders
  • Pancreatic function and diabetes
  • Diabetes Management and Research
  • Immune Cell Function and Interaction
  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Immunology Research
  • Diabetes Treatment and Management

Frequent collaborators in Alberto Pugliese's research include Mark A. Atkinson, Jay M. Sosenko, Carmella Evans-Molina, Irina Kusmartseva, and Jay S. Skyler.

The scientist has published extensively in various venues, with repeated contributions to:

  • Diabetes
  • Diabetologia
  • Diabetes Care
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications

Among their recent research publications are:

  • "Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19" (2020, Cell Metabolism)
  • "Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis" (2020, JCI Insight)
  • "Long-term culture of human pancreatic slices as a model to study real-time islet regeneration" (2020, Nature Communications)
  • "Altered β-Cell Prohormone Processing and Secretion in Type 1 Diabetes" (2021, Diabetes)
  • "Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes" (2021, Diabetologia)

Best Publications

  • The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes

    Alberto Pugliese;Markus Zeller;Alarico Fernandez;Laura J. Zalcberg

  • Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience.

    Tatiana Froud;Camillo Ricordi;David A. Baidal;Muhammad M. Hafiz

  • Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes.

    Martha Campbell-Thompson;Ann Fu;John S. Kaddis;Clive Wasserfall

  • Autoreactive T cells in type 1 diabetes

    Alberto Pugliese

  • Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients.

    Michelle Rosenzwajg;Guillaume Churlaud;Roberto Mallone;Adrien Six

  • Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes

    Jenny Aurielle B Babon;Megan E DeNicola;David M Blodgett;Inne Crèvecoeur

  • Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes

    Sarah J. Richardson;Teresa Rodriguez-Calvo;Ivan C. Gerling;Clayton E. Mathews

  • Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells

    Francesco Vendrame;Antonello Pileggi;Elsa Laughlin;Gloria Allende

  • Selective IL-2 responsiveness of regulatory T cells through multiple intrinsic mechanisms supports the use of low-dose IL-2 therapy in type 1 diabetes.

    Aixin Yu;Isaac Snowhite;Francesco Vendrame;Michelle Rosenzwajg;Michelle Rosenzwajg

  • Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes.

    Martha Campbell-Thompson;Clive Wasserfall;John Kaddis;Anastasia Albanese-O'Neill

  • Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis.

    G. Thomson;A. M. Valdes;A. M. Valdes;J. A. Noble;I. Kockum

  • Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele

    Simon T. Bennett;Amanda J. Wilson;Laura Esposito;Nourdine Bouzekri

  • The diagnosis of insulitis in human type 1 diabetes

    M. L. Campbell-Thompson;M. A. Atkinson;A. E. Butler;N. M. Chapman

  • Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes

    Federica Vecchio;Nicola Lo Buono;Angela Stabilini;Laura Nigi

  • Genetics of type 1 diabetes.

    Maria J Redondo;Andrea K Steck;Alberto Pugliese

  • Self-antigen–presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs

    Alberto Pugliese;Douglas Brown;David Garza;Djanira Murchison

  • Umbilical Cord Mesenchymal Stromal Cell With Autologous Bone Marrow Cell Transplantation in Established Type 1 Diabetes: A Pilot Randomized Controlled Open-Label Clinical Study to Assess Safety and Impact on Insulin Secretion

    Jinquan Cai;Zhixian Wu;Xiumin Xu;Lianming Liao

  • The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings.

    Alberto Pugliese;Mingder Yang;Irina Kusmarteva;Tiffany Heiple

  • Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19.

    Irina Kusmartseva;Wenting Wu;Farooq Syed;Verena Van Der Heide

  • Improved metabolic control and quality of life in seven patients with type 1 diabetes following islet after kidney transplantation.

    Pablo Cure;Antonello Pileggi;Tatiana Froud;Shari Messinger

Frequent Co-Authors

Mark A. Atkinson
Mark A. Atkinson University of Florida
Martha Campbell-Thompson
Martha Campbell-Thompson University of Florida
Camillo Ricordi
Camillo Ricordi University of Miami
Desmond A. Schatz
Desmond A. Schatz University of Florida
George S. Eisenbarth
George S. Eisenbarth University of Colorado Denver
Jay S. Skyler
Jay S. Skyler University of Miami
Clive Wasserfall
Clive Wasserfall University of Florida
Noel G. Morgan
Noel G. Morgan University of Exeter
Jerry P. Palmer
Jerry P. Palmer University of Washington
Alvin C. Powers
Alvin C. Powers Vanderbilt University Medical Center

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