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Best Female Scientists
2025

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Best Female Scientists

D-Index
119
Citations
54447
World Ranking
586
National Ranking
352

Immunology

D-Index
121
Citations
56407
World Ranking
325
National Ranking
206

Medicine

D-Index
121
Citations
56415
World Ranking
3597
National Ranking
1986

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Helen E. Heslop is affiliated with Baylor College of Medicine in the United States. Their research primarily focuses on medicine, with significant contributions to oncology, immunology, genetics, hematology, and molecular biology. The scientist's work includes investigations into CAR-T cell therapy research, virus-based gene therapy, immune cell function and interaction, hematopoietic stem cell transplantation, lymphoma diagnosis and treatment, viral infectious diseases and gene expression in insects, and acute lymphoblastic leukemia research.

Their recent papers include:

  • Anti-CD30 CAR-T Cell Therapy in Relapsed and Refractory Hodgkin Lymphoma (2020, Journal of Clinical Oncology)
  • Scalable Manufacturing of CAR T Cells for Cancer Immunotherapy (2021, Blood Cancer Discovery)
  • Unanswered questions following reports of secondary malignancies after CAR-T cell therapy (2024, Nature Medicine)
  • Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma (2020, Nature Communications)
  • Engineered off-the-shelf therapeutic T cells resist host immune rejection (2020, Nature Biotechnology)

Frequent co-authors include:

  • Malcolm K. Brenner
  • Premal Lulla
  • Carlos A. Ramos
  • Bambi Grilley
  • LaQuisa C. Hill

Helen E. Heslop has published extensively in the following venues:

  • Blood (24 publications)
  • Transplantation and Cellular Therapy (24 publications)
  • Journal of Clinical Oncology (12 publications)
  • Blood Advances (5 publications)
  • Molecular Therapy (4 publications)

The scientist's primary research topics can be summarized as:

  • CAR-T cell therapy research
  • Virus-based gene therapy research
  • Immune Cell Function and Interaction
  • Hematopoietic Stem Cell Transplantation
  • Lymphoma Diagnosis and Treatment
  • Viral Infectious Diseases and Gene Expression in Insects
  • Acute Lymphoblastic Leukemia research

Helen E. Heslop is a member of the Association of American Physicians.

Best Publications

  • Inducible apoptosis as a safety switch for adoptive cell therapy

    Antonio Di Stasi;Siok Keen Tey;Gianpietro Dotti;Yuriko Fujita

  • Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

    Martin A. Pule;Barbara Savoldo;G. Doug Myers;G. Doug Myers;Claudia Rossig

  • Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation.

    C.M Rooney;C.Y.C Ng;S Loftin;C.A Smith

  • Antitumor activity and long-term fate of chimeric antigen receptor–positive T cells in patients with neuroblastoma

    Chrystal U. Louis;Chrystal U. Louis;Barbara Savoldo;Barbara Savoldo;Gianpietro Dotti;Gianpietro Dotti;Martin Pule

  • Infusion of Cytotoxic T Cells for the Prevention and Treatment of Epstein-Barr Virus–Induced Lymphoma in Allogeneic Transplant Recipients

    Cliona M. Rooney;Colton A. Smith;Colton A. Smith;Catherine Y.C. Ng;Catherine Y.C. Ng;Susan K. Loftin;Susan K. Loftin

  • CD28 costimulation improves expansion and persistence of chimeric antigen receptor–modified T cells in lymphoma patients

    Barbara Savoldo;Carlos Almeida Ramos;Carlos Almeida Ramos;Enli Liu;Martha P. Mims

  • Human Epidermal Growth Factor Receptor 2 (HER2) –Specific Chimeric Antigen Receptor–Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma

    Nabil Ahmed;Vita S. Brawley;Meenakshi Hegde;Catherine Robertson

  • Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes

    Helen E. Heslop;Catherine Y.C. Ng;Congfen Li;Colton A. Smith

  • Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients

    Helen E. Heslop;Karen S. Slobod;Martin A. Pule;Gregory A. Hale

  • An inducible caspase 9 safety switch for T-cell therapy

    Karin C. Straathof;Martin A. Pulè;Patricia Yotnda;Gianpietro Dotti

  • HER2-Specific Chimeric Antigen Receptor–Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial

    Nabil Ahmed;Nabil Ahmed;Vita Brawley;Vita Brawley;Meenakshi Hegde;Meenakshi Hegde;Kevin Bielamowicz

  • Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15

    Yang Xu;Ming Zhang;Carlos A. Ramos;April Durett

  • Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals.

    Ann M. Leen;G. Doug Myers;Uluhan Sili;M. Helen Huls

  • Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety

    Valentina Hoyos;Barbara Savoldo;Barbara Savoldo;Concetta Quintarelli;Aruna Mahendravada

  • Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation

    Ann M. Leen;Catherine M. Bollard;Adam M. Mendizabal;Elizabeth J. Shpall

  • A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells

    Martin A. Pulè;Karin C. Straathof;Karin C. Straathof;Gianpietro Dotti;Gianpietro Dotti;Helen E. Heslop

  • T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model.

    Antonio Di Stasi;Biagio De Angelis;Cliona M. Rooney;Lan Zhang

  • Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study

    Conrad Russell Y. Cruz;Kenneth P. Micklethwaite;Barbara Savoldo;Carlos A. Ramos

  • Post-transplant lymphoproliferative disorders.

    Stephen Gottschalk;Cliona M. Rooney;Helen E. Heslop

  • Sustained Complete Responses in Patients With Lymphoma Receiving Autologous Cytotoxic T Lymphocytes Targeting Epstein-Barr Virus Latent Membrane Proteins

    Catherine M. Bollard;Catherine M. Bollard;Stephen Gottschalk;Stephen Gottschalk;Vicky Torrano;Vicky Torrano;Oumar Diouf;Oumar Diouf

  • Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells

    Donna R. Rill;Donna R. Rill;Victor M. Santana;Victor M. Santana;W. Mark Roberts;W. Mark Roberts;Terri Nilson;Terri Nilson

Frequent Co-Authors

Malcolm K. Brenner
Malcolm K. Brenner Baylor College of Medicine
Cliona M. Rooney
Cliona M. Rooney Baylor College of Medicine
Catherine M. Bollard
Catherine M. Bollard George Washington University
Adrian P. Gee
Adrian P. Gee Baylor College of Medicine
Ann M. Leen
Ann M. Leen Baylor College of Medicine
Gianpietro Dotti
Gianpietro Dotti University of North Carolina at Chapel Hill
Stephen Gottschalk
Stephen Gottschalk St. Jude Children's Research Hospital
Barbara Savoldo
Barbara Savoldo University of North Carolina at Chapel Hill
Hao Liu
Hao Liu Indiana University
Elizabeth J. Shpall
Elizabeth J. Shpall The University of Texas MD Anderson Cancer Center

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