World's Best Scientists 2026 revealed!
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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
122
Citations
53561
World Ranking
503
National Ranking
296

Immunology

D-Index
122
Citations
55244
World Ranking
319
National Ranking
202

Medicine

D-Index
122
Citations
55298
World Ranking
3475
National Ranking
1910

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award

Overview

Cliona M. Rooney is affiliated with Baylor College of Medicine in the United States. Their research primarily focuses on medicine, with significant contributions in immunology and microbiology. Rooney's subfields of study emphasize oncology, immunology, genetics, pathology and forensic medicine, and molecular biology.

The scientist's work addresses multiple main topics, notably:

  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Lymphoma Diagnosis and Treatment
  • Virus-based gene therapy research
  • Immunotherapy and Immune Responses
  • Viral-associated cancers and disorders
  • Cancer Immunotherapy and Biomarkers

Rooney has published extensively in several key venues, including:

  • Blood
  • Journal of Clinical Oncology
  • Cytotherapy
  • Transplantation and Cellular Therapy
  • UNC Libraries

Recent papers demonstrate a focus on CAR-T cell therapies and oncolytic virus strategies within hematologic and solid tumor contexts. Selected recent works include:

  • "Anti-CD30 CAR-T Cell Therapy in Relapsed and Refractory Hodgkin Lymphoma," 2020, Journal of Clinical Oncology
  • "CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity," 2021, Blood
  • "Oncolytic measles virus therapy enhances tumor antigen-specific T-cell responses in patients with multiple myeloma," 2020, Leukemia
  • "HER2-Specific Chimeric Antigen Receptor-Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial," 2020, UNC Libraries
  • "Phase I Trial of GD2.CART Cells Augmented With Constitutive Interleukin-7 Receptor for Treatment of High-Grade Pediatric CNS Tumors," 2024, Journal of Clinical Oncology

Research collaborations are evident with frequent co-authors such as Helen E. Heslop, Premal Lulla, Bilal Omer, Malcolm K. Brenner, and Bambi Grilley.

Best Publications

  • Inducible apoptosis as a safety switch for adoptive cell therapy

    Antonio Di Stasi;Siok Keen Tey;Gianpietro Dotti;Yuriko Fujita

  • Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

    Martin A. Pule;Barbara Savoldo;G. Doug Myers;G. Doug Myers;Claudia Rossig

  • Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation.

    C.M Rooney;C.Y.C Ng;S Loftin;C.A Smith

  • Antitumor activity and long-term fate of chimeric antigen receptor–positive T cells in patients with neuroblastoma

    Chrystal U. Louis;Chrystal U. Louis;Barbara Savoldo;Barbara Savoldo;Gianpietro Dotti;Gianpietro Dotti;Martin Pule

  • Infusion of Cytotoxic T Cells for the Prevention and Treatment of Epstein-Barr Virus–Induced Lymphoma in Allogeneic Transplant Recipients

    Cliona M. Rooney;Colton A. Smith;Colton A. Smith;Catherine Y.C. Ng;Catherine Y.C. Ng;Susan K. Loftin;Susan K. Loftin

  • CD28 costimulation improves expansion and persistence of chimeric antigen receptor–modified T cells in lymphoma patients

    Barbara Savoldo;Carlos Almeida Ramos;Carlos Almeida Ramos;Enli Liu;Martha P. Mims

  • Human Epidermal Growth Factor Receptor 2 (HER2) –Specific Chimeric Antigen Receptor–Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma

    Nabil Ahmed;Vita S. Brawley;Meenakshi Hegde;Catherine Robertson

  • Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes

    Helen E. Heslop;Catherine Y.C. Ng;Congfen Li;Colton A. Smith

  • Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients

    Helen E. Heslop;Karen S. Slobod;Martin A. Pule;Gregory A. Hale

  • Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer

    Jeong Heo;Tony Reid;Leyo Ruo;Caroline J. Breitbach

  • An inducible caspase 9 safety switch for T-cell therapy

    Karin C. Straathof;Martin A. Pulè;Patricia Yotnda;Gianpietro Dotti

  • HER2-Specific Chimeric Antigen Receptor–Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial

    Nabil Ahmed;Nabil Ahmed;Vita Brawley;Vita Brawley;Meenakshi Hegde;Meenakshi Hegde;Kevin Bielamowicz

  • Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15

    Yang Xu;Ming Zhang;Carlos A. Ramos;April Durett

  • Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals.

    Ann M. Leen;G. Doug Myers;Uluhan Sili;M. Helen Huls

  • Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety

    Valentina Hoyos;Barbara Savoldo;Barbara Savoldo;Concetta Quintarelli;Aruna Mahendravada

  • Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation

    Ann M. Leen;Catherine M. Bollard;Adam M. Mendizabal;Elizabeth J. Shpall

  • A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells

    Martin A. Pulè;Karin C. Straathof;Karin C. Straathof;Gianpietro Dotti;Gianpietro Dotti;Helen E. Heslop

  • T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model.

    Antonio Di Stasi;Biagio De Angelis;Cliona M. Rooney;Lan Zhang

  • Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study

    Conrad Russell Y. Cruz;Kenneth P. Micklethwaite;Barbara Savoldo;Carlos A. Ramos

  • Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b

    John A. Craddock;An Lu;Adham Bear;Martin Pule

  • Post-transplant lymphoproliferative disorders.

    Stephen Gottschalk;Cliona M. Rooney;Helen E. Heslop

Frequent Co-Authors

Helen E. Heslop
Helen E. Heslop Baylor College of Medicine
Malcolm K. Brenner
Malcolm K. Brenner Baylor College of Medicine
Ann M. Leen
Ann M. Leen Baylor College of Medicine
Catherine M. Bollard
Catherine M. Bollard George Washington University
Adrian P. Gee
Adrian P. Gee Baylor College of Medicine
Gianpietro Dotti
Gianpietro Dotti University of North Carolina at Chapel Hill
Barbara Savoldo
Barbara Savoldo University of North Carolina at Chapel Hill
Stephen Gottschalk
Stephen Gottschalk St. Jude Children's Research Hospital
Hao Liu
Hao Liu Indiana University
Elizabeth J. Shpall
Elizabeth J. Shpall The University of Texas MD Anderson Cancer Center

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