World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
23385
World Ranking
5853
National Ranking
2771

Overview

Lee-Way Jin is affiliated with the University of California, Davis in the United States. Their research spans several key areas within medicine and biochemistry, genetics, and molecular biology. This work is distributed across various subfields, including molecular biology, physiology, neurology, psychiatry and mental health, and genetics.

Their publications focus extensively on neurobiological disorders, particularly dementia and cognitive impairment. Key topics of investigation include dementia and cognitive impairment research, Alzheimer's disease research and treatments, neuroinflammation and neurodegeneration mechanisms, tryptophan's role in brain disorders, glycosylation and glycoproteins research, glioma diagnosis and treatment, and the intersection of diabetes, cardiovascular risks, and lipoproteins.

Lee-Way Jin has contributed to multiple research papers, including the following recent works:

  • Biophysical basis for Kv1.3 regulation of membrane potential changes induced by P2X4-mediated calcium entry in microglia, 2020, published in Glia
  • Transcriptomic and glycomic analyses highlight pathway-specific glycosylation alterations unique to Alzheimer's disease, 2023, published in Scientific Reports
  • Ketogenic diet and BHB rescue the fall of long-term potentiation in an Alzheimer's mouse model and stimulates synaptic plasticity pathway enzymes, 2024, published in Communications Biology
  • 1700 nm optical coherence microscopy enables minimally invasive, label-free, in vivo optical biopsy deep in the mouse brain, 2021, published in Light Science & Applications
  • HDAC1 dysregulation induces aberrant cell cycle and DNA damage in progress of TDP-43 proteinopathies, 2020, published in EMBO Molecular Medicine

The scientist frequently publishes in venues such as Alzheimer's & Dementia, bioRxiv (Cold Spring Harbor Laboratory), The FASEB Journal, Glia, and the Journal of Neuropathology & Experimental Neurology. Alzheimer's & Dementia represents their most frequent publication venue, with 29 contributions.

Collaboration is a notable aspect of Lee-Way Jin's scholarly activity. Frequent co-authors include Izumi Maezawa, Charles DeCarli, Carlito B. Lebrilla, Brittany N. Dugger, and Angela M. Zivkovic.

Best Publications

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease.

    Jin Xu;Shyan Yuan Kao;Frank J S Lee;Weihong Song

  • The regulation of amyloid β protein precursor secretion and its modulatory role in cell adhesion

    D. Schubert;Lee-Way Jin;T. Saitoh;Greg Cole

  • Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

    Eric M Reiman;Joseph F Arboleda-Velasquez;Yakeel T Quiroz;Matthew J Huentelman

  • Reduced Hippocampal Insulin-Degrading Enzyme in Late-Onset Alzheimer's Disease Is Associated with the Apolipoprotein E-ε4 Allele

    David G. Cook;David G. Cook;James B. Leverenz;James B. Leverenz;Pamela J. McMillan;Pamela J. McMillan;J. Jacob Kulstad;J. Jacob Kulstad

  • Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation

    Sylvia Villeneuve;Gil D. Rabinovici;Gil D. Rabinovici;Gil D. Rabinovici;Brendan I. Cohn-Sheehy;Brendan I. Cohn-Sheehy;Brendan I. Cohn-Sheehy;Cindee Madison

  • Rett Syndrome Microglia Damage Dendrites and Synapses by the Elevated Release of Glutamate

    Izumi Maezawa;Lee-Way Jin

  • Gram-negative bacterial molecules associate with Alzheimer disease pathology

    Xinhua Zhan;Boryana Stamova;Lee Way Jin;Charles Decarli

  • Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

    David C. Whitcomb;Jessica LaRusch;Alyssa M. Krasinskas;Lambertus Klei

  • Amylin deposition in the brain: A second amyloid in Alzheimer disease?

    Kaleena Jackson;Gustavo A. Barisone;Elva Diaz;Lee-way Jin

  • Rett Syndrome Astrocytes Are Abnormal and Spread MeCP2 Deficiency through Gap Junctions

    Izumi Maezawa;Susan Swanberg;Danielle J Harvey;Janine M LaSalle

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    G. Jun;C. A. Ibrahim-Verbaas;M. Vronskaya;J-C Lambert;J-C Lambert;J-C Lambert

  • Diet-induced hypercholesterolemia enhances brain Aβ accumulation in transgenic mice

    Feng Shiun Shie;Lee Way Jin;David G. Cook;James B. Leverenz

  • Amyloid-β protein oligomer at low nanomolar concentrations activates microglia and induces microglial neurotoxicity

    Izumi Maezawa;Pavel I. Zimin;Heike Wulff;Lee-Way Jin

  • Intracellular Accumulation of Amyloidogenic Fragments of Amyloid-β Precursor Protein in Neurons with Niemann-Pick Type C Defects Is Associated with Endosomal Abnormalities

    Lee Way Jin;Izumi Maezawa;Inez Vincent;Thomas Bird

  • Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension.

    Lee-Way Jin;Haruaki Ninomiya;Jean Marc Roch;David Schubert

  • Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

    Giovanni Coppola;Subashchandrabose Chinnathambi;Jason Ji Yong Lee;Beth A. Dombroski

  • Congo red and thioflavin-T analogs detect Aβ oligomers

    Izumi Maezawa;Hyun Seok Hong;Ruiwu Liu;Chun Yi Wu

  • Imaging linear birefringence and dichroism in cerebral amyloid pathologies

    Lee Way Jin;Kacey A. Claborn;Miki Kurimoto;Morten A. Geday

Frequent Co-Authors

Charles DeCarli
Charles DeCarli University of California, Davis
Heike Wulff
Heike Wulff University of California, Davis
Bruce L. Miller
Bruce L. Miller University of California, San Francisco
John M Olichney
John M Olichney University of California, Davis
William W. Seeley
William W. Seeley University of California, San Francisco
William J. Jagust
William J. Jagust University of California, Berkeley
Eliezer Masliah
Eliezer Masliah National Institutes of Health
Gil D. Rabinovici
Gil D. Rabinovici University of California, San Francisco
Peter St George-Hyslop
Peter St George-Hyslop Columbia University
Thomas D. Bird
Thomas D. Bird University of Washington

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can open doors to a wide range of online degrees and health-related career paths. For those interested in the diagnostic side of medicine, consider enrolling in the best online radiology tech programs. These programs offer flexibility and affordability for aspiring radiologic technologists.

Nutrition is another growing field linked to biochemistry studies. If you want to specialize in diet and health, check out reputable dietitian masters programs available online. These degrees can qualify you for advanced roles in nutrition counseling, research, or clinical settings.

For students seeking quicker entry into the healthcare workforce, online medical assistant programs with financial aid can be a strong starting point. Many programs offer flexible schedules and support for students who need financial assistance.

Already working as a medical assistant? Consider advancing your career with a bridge program, such as the medical assistant to lpn route, which prepares graduates for even greater responsibilities in patient care.

Best Scientists Citing Lee-Way Jin

Trending Scientists

Recently Published Articles