Heike Wulff spends much of her time researching Potassium channel, Pharmacology, Cell biology, Immunology and T cell. Her Potassium channel research is multidisciplinary, incorporating perspectives in Experimental autoimmune encephalomyelitis and Neuroscience. Her research in Pharmacology intersects with topics in Voltage-gated ion channel, Adoptive cell transfer, Voltage-gated potassium channel, Inward-rectifier potassium ion channel and Effector.
Her Cell biology research incorporates themes from Cell, Biochemistry, Voltage-dependent calcium channel, Margatoxin and Ion channel. The study incorporates disciplines such as Pathology and Stichodactyla helianthus in addition to Immunology. Her Potassium channel blocker study combines topics in areas such as Inflammation, K channels and Channel blocker.
Heike Wulff mostly deals with Pharmacology, Potassium channel, Internal medicine, Cell biology and Stereochemistry. Her work deals with themes such as Inflammation, Immunology, GABAA receptor, Membrane potential and In vivo, which intersect with Pharmacology. Her research integrates issues of Blockade, Biochemistry and Ion channel in her study of Potassium channel.
Heike Wulff combines subjects such as Endocrinology and Cardiology with her study of Internal medicine. Her study looks at the relationship between Cell biology and topics such as Microglia, which overlap with Neuroinflammation, Neurotoxicity and Neuroscience. Her research investigates the connection between Stereochemistry and topics such as Binding site that intersect with issues in Biophysics.
Her main research concerns Potassium channel, Pharmacology, Microglia, Cell biology and Neuroinflammation. Heike Wulff is interested in Voltage-gated potassium channel, which is a branch of Potassium channel. As part of the same scientific family, Heike Wulff usually focuses on Pharmacology, concentrating on GABAA receptor and intersecting with Convulsant, Subtype selectivity and Binding site.
Her Microglia research includes themes of Neurodegeneration, Disease, Long-term potentiation, Kir2.1 and Neuroscience. Her research investigates the connection with Neuroinflammation and areas like Hippocampal formation which intersect with concerns in Amyloid. Her In vivo research includes elements of Effector, Cell, Cell-penetrating peptide and Lymphocyte.
Her primary scientific interests are in Microglia, Potassium channel, Neuroscience, Neuroinflammation and Receptor. She has included themes like Lipopolysaccharide, Hippocampal formation, Long-term potentiation, Kir2.1 and Cell biology in her Microglia study. The Potassium channel study combines topics in areas such as Purinergic receptor, Calcium, Function, Ion channel and Parenchyma.
The various areas that Heike Wulff examines in her Neuroinflammation study include Leukemia, Downregulation and upregulation, Cell type and Small molecule. Her Tetramethylenedisulfotetramine research is multidisciplinary, relying on both Zebrafish, Antagonist and Pharmacology, Diazepam. Her study in Pharmacology is interdisciplinary in nature, drawing from both Competitive antagonist, Allosteric modulator, Bicuculline and Neuroactive steroid.
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International Union of Pharmacology. LIII. Nomenclature and Molecular Relationships of Voltage-Gated Potassium Channels
Aguan D. Wei;George A. Gutman;Richard W Aldrich;K. George Chandy.
Pharmacological Reviews (2005)
Voltage-gated potassium channels as therapeutic targets
Heike Wulff;Neil A. Castle;Luis A. Pardo.
Nature Reviews Drug Discovery (2009)
Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: A potential immunosuppressant
Heike Wulff;Mark J. Miller;Wolfram Hänsel;Stephan Grissmer.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases
Christine Beeton;Heike Wulff;Nathan E. Standifer;Philippe Azam.
Proceedings of the National Academy of Sciences of the United States of America (2006)
International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels : potassium channels
George A. Gutman;K. George Chandy;John P. Adelman;Jayashree Aiyar.
Pharmacological Reviews (2003)
K+ channels as targets for specific immunomodulation.
K. George Chandy;Heike Wulff;Christine Beeton;Michael Pennington.
Trends in Pharmacological Sciences (2004)
The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS
Heike Wulff;Peter A. Calabresi;Rameeza Allie;Sung Yun.
Journal of Clinical Investigation (2003)
Up-regulation of the IKCa1 Potassium Channel during T-cell Activation MOLECULAR MECHANISM AND FUNCTIONAL CONSEQUENCES
Sanjiv Ghanshani;Heike Wulff;Mark J. Miller;Heike Rohm.
Journal of Biological Chemistry (2000)
Selective blockade of T lymphocyte K+ channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis
Christine Beeton;Heike Wulff;Jocelyne Barbaria;Olivier Clot-Faybesse.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Ion Channels in Innate and Adaptive Immunity
Stefan Feske;Heike Wulff;Edward Y Skolnik.
Annual Review of Immunology (2015)
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