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Biology and Biochemistry

D-Index
68
Citations
23992
World Ranking
7648
National Ranking
3481

Overview

Stefan Feske is affiliated with New York University in the United States. Their research primarily focuses on the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. The scientist's work spans several subfields, including Immunology, Molecular Biology, Sensory Systems, Physiology, and Genetics.

The main topics addressed in Stefan Feske's research cover Ion Channels and Receptors, Immune Cell Function and Interaction, Salivary Gland Disorders and Functions, Herbal Medicine Research Studies, Inflammatory Bowel Disease, RNA modifications and cancer, and T-cell and B-cell Immunology.

Frequent co-authors collaborating with Stefan Feske include Yin-Hu Wang, Anthony Tao, Ulrike Kaufmann, Lucile Noyer, and Carl Weidinger.

The scientist's research has been published extensively in various academic venues. Notable frequent publication venues are bioRxiv (Cold Spring Harbor Laboratory), Nature Immunology, Nature Communications, Journal of Crohn's and Colitis, and EMBO Molecular Medicine.

Recent papers by Stefan Feske feature the following works:

  • CRAC Channels and Calcium Signaling in T Cell-Mediated Immunity, 2020, Trends in Immunology
  • The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling, 2022, Nature Immunology
  • The function of Wtap in N6-adenosine methylation of mRNAs controls T cell receptor signaling and survival of T cells, 2022, Nature Immunology
  • Calcium regulation of T cell metabolism, 2020, Current Opinion in Physiology
  • Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses, 2021, Nature Immunology

Best Publications

  • A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

    Stefan Feske;Yousang Gwack;Murali Prakriya;Sonal Srikanth

  • Orai1 is an essential pore subunit of the CRAC channel

    Murali Prakriya;Stefan Feske;Yousang Gwack;Sonal Srikanth

  • Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

    Ping Chih Ho;Jessica Dauz Bihuniak;Andrew N. MacIntyre;Matthew Staron

  • Calcium signalling in lymphocyte activation and disease.

    Stefan Feske

  • Gene regulation mediated by calcium signals in T lymphocytes.

    Stefan Feske;Jena Giltnane;Ricardo Dolmetsch;Louis M. Staudt

  • Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance.

    Masatsugu Oh-hora;Megumi Yamashita;Patrick G Hogan;Sonia Sharma

  • Ion Channels in Innate and Adaptive Immunity

    Stefan Feske;Heike Wulff;Edward Y Skolnik

  • Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins.

    Vigo Heissmeyer;Fernando Macián;Fernando Macián;Sin Hyeog Im;Sin Hyeog Im;Rajat Varma

  • STIM1 Mutation Associated with a Syndrome of Immunodeficiency and Autoimmunity

    Capucine Picard;Christie Ann McCarl;Alexander Papolos;Sara Khalil

  • A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT

    Yousang Gwack;Sonia Sharma;Julie Nardone;Bogdan Tanasa

  • Ion channels and transporters in lymphocyte function and immunity

    Stefan Feske;Edward Y. Skolnik;Murali Prakriya

  • Biochemical and functional characterization of Orai proteins.

    Yousang Gwack;Sonal Srikanth;Stefan Feske;Fernando Cruz-Guilloty

  • Diseases caused by mutations in ORAI1 and STIM1

    Rodrigo S. Lacruz;Stefan Feske

  • Perforin Triggers a Plasma Membrane-Repair Response that Facilitates CTL Induction of Apoptosis

    Dennis Keefe;Lianfa Shi;Lianfa Shi;Stefan Feske;Stefan Feske;Ramiro Massol;Ramiro Massol

  • Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes.

    Yousang Gwack;Stefan Feske;Sonal Srikanth;Patrick G Hogan

  • ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia

    Christie-Ann McCarl;Christie-Ann McCarl;Capucine Picard;Capucine Picard;Sara Khalil;Takumi Kawasaki

  • Hair loss and defective T- and B-cell function in mice lacking ORAI1.

    Yousang Gwack;Sonal Srikanth;Masatsugu Oh-hora;Patrick G. Hogan

  • ORAI1 and STIM1 deficiency in human and mice: roles of store‐operated Ca2+ entry in the immune system and beyond

    Stefan Feske

  • Whole-exome sequencing-based discovery of STIM1 deficiency in a child with fatal classic Kaposi sarcoma

    Minji Byun;Avinash Abhyankar;Virginie Lelarge;Sabine Plancoulaine;Sabine Plancoulaine

  • Reduced Synaptic STIM2 Expression and Impaired Store-Operated Calcium Entry Cause Destabilization of Mature Spines in Mutant Presenilin Mice

    Suya Sun;Hua Zhang;Jie Liu;Elena Popugaeva

Frequent Co-Authors

Anjana Rao
Anjana Rao La Jolla Institute For Allergy & Immunology
Capucine Picard
Capucine Picard Université Paris Cité
Stephan Ehl
Stephan Ehl University of Freiburg
Alain Fischer
Alain Fischer Collège de France
Derya Unutmaz
Derya Unutmaz University of Connecticut
Indu S. Ambudkar
Indu S. Ambudkar National Institutes of Health
Frédéric Rieux-Laucat
Frédéric Rieux-Laucat Université Paris Cité
Raif S. Geha
Raif S. Geha Boston Children's Hospital
Hans-Hartmut Peter
Hans-Hartmut Peter University of Freiburg
Thomas B. Issekutz
Thomas B. Issekutz Dalhousie University

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