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Frédéric Rieux-Laucat

Frédéric Rieux-Laucat

D-Index & Metrics

Immunology

D-Index
73
Citations
25616
World Ranking
2099
National Ranking
82

Overview

Frédéric Rieux-Laucat is affiliated with Université Paris Cité in France. Their research spans multiple fields primarily centered on medicine with a specific focus on immunology and microbiology. The scientist also contributes extensively to biochemistry, genetics, and molecular biology.

Their main subfields of study include immunology, molecular biology, genetics, infectious diseases, and oncology. The core topics covered in their work are:

  • Immunodeficiency and Autoimmune Disorders
  • Immune Cell Function and Interaction
  • Interferon and Immune Responses
  • COVID-19 Clinical Research Studies
  • Inflammasome and Immune Disorders
  • T-cell and B-cell Immunology
  • NF-κB Signaling Pathways

Frequent publication venues for their research are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Allergy and Clinical Immunology
  • La Revue de Médecine Interne
  • Journal of Clinical Immunology
  • Blood

Their recent papers illustrate a focus on immune response mechanisms, particularly related to severe COVID-19 and autoimmunity:

  • "Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients", 2020, Science
  • "Autoantibodies against type I IFNs in patients with life-threatening COVID-19", 2020, Science
  • "NF-κB: At the Borders of Autoimmunity and Inflammation", 2021, Frontiers in Immunology
  • "Impaired type I interferon activity and exacerbated inflammatory responses in severe Covid-19 patients", 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Overview of STING-Associated Vasculopathy with Onset in Infancy (SAVI) Among 21 Patients", 2020, The Journal of Allergy and Clinical Immunology In Practice

Collaboration appears integral to their work, with frequent co-authors including Jérôme Hadjadj, Darragh Duffy, Marie-Claude Stolzenberg, Capucine Pïcard, and Bénédicte Neven. The counts of joint publications with these collaborators are substantial, indicating sustained research partnerships.

Best Publications

  • Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients.

    Jérôme Hadjadj;Nader Yatim;Laura Barnabei;Aurélien Corneau

  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

    Paul Bastard;Paul Bastard;Paul Bastard;Lindsey B. Rosen;Qian Zhang;Eleftherios Michailidis

  • Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity

    F. Rieux-Laucat;F. Le Deist;C. Hivroz;I. A. G. Roberts

  • XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome

    Stéphanie Rigaud;Marie-Claude Fondanèche;Nathalie Lambert;Nathalie Lambert;Benoit Pasquier

  • Efficacy of Gene Therapy for X-Linked Severe Combined Immunodeficiency

    Salima Hacein-Bey-Abina;Julia Hauer;Annick Lim;Capucine Picard

  • Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

    Paul Bastard;Adrian Gervais;Adrian Gervais;Tom Le Voyer;Tom Le Voyer;Jérémie Rosain;Jérémie Rosain

  • The European Society for Immunodeficiencies (ESID) Registry Working Definitions for the Clinical Diagnosis of Inborn Errors of Immunity

    Markus G. Seidel;Gerhard Kindle;Benjamin Gathmann;Isabella Quinti

  • Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations

    Nadia Jeremiah;Bénédicte Neven;Matteo Gentili;Isabelle Callebaut

  • STIM1 Mutation Associated with a Syndrome of Immunodeficiency and Autoimmunity

    Capucine Picard;Christie Ann McCarl;Alexander Papolos;Sara Khalil

  • Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop.

    Joao B. Oliveira;Jack J. Bleesing;Umberto Dianzani;Thomas A. Fleisher

  • NF-κB: At the Borders of Autoimmunity and Inflammation.

    Laura Barnabei;Emmanuel Laplantine;William Mbongo;Frédéric Rieux-Laucat

  • Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study.

    Tanya I Coulter;Anita Chandra;Chris M Bacon;Judith Babar

  • Detection of interferon alpha protein reveals differential levels and cellular sources in disease.

    Mathieu P. Rodero;Jérémie Decalf;Jérémie Decalf;Vincent Bondet;Vincent Bondet;David Hunt;David Hunt

  • Autoimmune Lymphoproliferative Syndrome with Somatic Fas Mutations

    Eliska Holzelova;Cédric Vonarbourg;Marie Claude Stolzenberg;Peter D. Arkwright

  • Severe Food Allergy as a Variant of IPEX Syndrome Caused by a Deletion in a Noncoding Region of the FOXP3 Gene

    Troy R Torgerson;Avriel Linane;Nicolette Moes;Stephanie Anover

  • Autoimmune lymphoproliferative syndromes: genetic defects of apoptosis pathways.

    F Rieux-Laucat;F Le Deist;A Fischer

  • Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study

    Federica Barzaghi;Laura Cristina Amaya Hernandez;Benedicte Neven;Silvia Ricci

  • MST1 mutations in autosomal recessive primary immunodeficiency characterized by defective naive T-cell survival

    Nadine T. Nehme;Nadine T. Nehme;Jana Pachlopnik Schmid;Jana Pachlopnik Schmid;Franck Debeurme;Franck Debeurme;Isabelle André-Schmutz;Isabelle André-Schmutz

  • Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes.

    Silvia Cerboni;Nadia Jeremiah;Matteo Gentili;Ulf Gehrmann

  • Defective IL10 Signaling Defining a Subgroup of Patients With Inflammatory Bowel Disease

    Bernadette Begue;Julien Verdier;Frédéric Rieux-Laucat;Olivier Goulet

  • Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature.

    Tracy A. Briggs;Gillian I. Rice;Sarah Daly;Jill Urquhart

  • Impaired type I interferon activity and exacerbated inflammatory responses in severe Covid-19 patients

    Jerome Hadjadj;Nader Yatim;Laura Barnabei;Aurelien Corneau

Frequent Co-Authors

Alain Fischer
Alain Fischer Collège de France
Capucine Picard
Capucine Picard Université Paris Cité
Bénédicte Neven
Bénédicte Neven Université Paris Cité
Frank M. Ruemmele
Frank M. Ruemmele Necker-Enfants Malades Hospital
Nadine Cerf-Bensussan
Nadine Cerf-Bensussan Université Paris Cité
Yanick J. Crow
Yanick J. Crow Université Paris Cité
Olivier Hermine
Olivier Hermine Necker-Enfants Malades Hospital
Stéphane Blanche
Stéphane Blanche Université Paris Cité
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Françoise Le Deist
Françoise Le Deist University of Montreal

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