Fellow of The Academy of Medical Sciences, United Kingdom
Yanick J. Crow mainly focuses on Immunology, Genetics, Aicardi–Goutières syndrome, Interferon and Innate immune system. His research combines Disease and Immunology. His Mutation, Locus, Gene and ASPM study in the realm of Genetics interacts with subjects such as CDK5RAP2.
The concepts of his Mutation study are interwoven with issues in Cerebral cortex, Cancer research, Endonuclease complex and Virology. His study in Aicardi–Goutières syndrome is interdisciplinary in nature, drawing from both Biomarker, Aicardi syndrome, Alu element and Mendelian disorders. His Interferon research includes elements of RNA, Downregulation and upregulation, Immunity and Cell biology.
Yanick J. Crow focuses on Immunology, Genetics, Aicardi–Goutières syndrome, Interferon and Pathology. His study in the fields of Innate immune system, Interferon type I and Autoimmunity under the domain of Immunology overlaps with other disciplines such as Sting. Mutation, Gene, Phenotype, Locus and Genetic heterogeneity are the core of his Genetics study.
His Missense mutation study, which is part of a larger body of work in Mutation, is frequently linked to Singleton Merten syndrome and Context, bridging the gap between disciplines. The various areas that he examines in his Aicardi–Goutières syndrome study include Aicardi syndrome, Encephalopathy and Alpha interferon. His Interferon study integrates concerns from other disciplines, such as Cancer research, Downregulation and upregulation, Janus kinase 1, Molecular biology and Cell biology.
His primary areas of investigation include Interferon, Immunology, Genetics, Aicardi–Goutières syndrome and Disease. His studies deal with areas such as Phenotype, Gene, Wild type and Stimulator of interferon genes as well as Interferon. His biological study spans a wide range of topics, including Molecular biology and Cell biology.
Yanick J. Crow interconnects Downregulation and upregulation and Lung injury in the investigation of issues within Immunology. His study on Genotype, Proband and Zebrafish is often connected to Ribosome biogenesis and RRNA processing as part of broader study in Genetics. His Aicardi–Goutières syndrome study incorporates themes from Failure to thrive, Alpha interferon, Bioinformatics and Immunodeficiency.
Yanick J. Crow mostly deals with Interferon, Mutation, Sting, Immunology and Cell biology. His Interferon research is multidisciplinary, incorporating elements of STAT2, Transcription, stat, Transcription factor and Loss of heterozygosity. His Mutation study combines topics from a wide range of disciplines, such as Phenotype, Gene silencing, Golgi apparatus and Pathology.
Yanick J. Crow studies Aicardi–Goutières syndrome, a branch of Phenotype. Yanick J. Crow works on Immunology which deals in particular with Interferon-stimulated gene. The Cell biology study combines topics in areas such as Inflammation, HEK 293 cells, Protein subunit, Gene and Immune system.
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HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
David C. Goldstone;Valerie Ennis-Adeniran;Joseph J. Hedden;Harriet C. T. Groom.
Nature (2011)
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus.
Yanick J Crow;Yanick J Crow;Bruce E Hayward;Rekha Parmar;Peter Robins.
Nature Genetics (2006)
International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity
Capucine Picard;H. Bobby Gaspar;Waleed Al-Herz;Aziz Bousfiha.
Journal of Clinical Immunology (2018)
Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response.
Gillian I Rice;Jacquelyn Bond;Aruna Asipu;Rebecca L Brunette.
Nature Genetics (2009)
ASPM is a major determinant of cerebral cortical size.
Jacquelyn Bond;Emma Roberts;Ganesh H. Mochida;Ganesh H. Mochida;Daniel J. Hampshire.
Nature Genetics (2002)
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection.
Yanick J Crow;Yanick J Crow;Andrea Leitch;Bruce E Hayward;Anna Garner.
Nature Genetics (2006)
Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature
Gillian I. Rice;Paul R. Kasher;Gabriella M A Forte;Niamh M. Mannion.
Nature Genetics (2012)
Large-scale discovery of novel genetic causes of developmental disorders
T.W. Fitzgerald;S.S. Gerety;W.D. Jones;M. van Kogelenberg.
Nature (2015)
Aicardi–Goutières syndrome and the type I interferonopathies
Yanick J. Crow;Nicolas Manel.
Nature Reviews Immunology (2015)
The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies.
Aziz Bousfiha;Leïla Jeddane;Capucine Picard;Fatima Ailal.
Journal of Clinical Immunology (2018)
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