D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 83 Citations 25,041 314 World Ranking 10463 National Ranking 309
Genetics D-index 79 Citations 23,435 255 World Ranking 1073 National Ranking 41

Research.com Recognitions

Awards & Achievements

Fellow of The Academy of Medical Sciences, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Mutation
  • Internal medicine

Yanick J. Crow mainly focuses on Immunology, Genetics, Aicardi–Goutières syndrome, Interferon and Innate immune system. His research combines Disease and Immunology. His Mutation, Locus, Gene and ASPM study in the realm of Genetics interacts with subjects such as CDK5RAP2.

The concepts of his Mutation study are interwoven with issues in Cerebral cortex, Cancer research, Endonuclease complex and Virology. His study in Aicardi–Goutières syndrome is interdisciplinary in nature, drawing from both Biomarker, Aicardi syndrome, Alu element and Mendelian disorders. His Interferon research includes elements of RNA, Downregulation and upregulation, Immunity and Cell biology.

His most cited work include:

  • Large-scale discovery of novel genetic causes of developmental disorders (661 citations)
  • Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus. (605 citations)
  • Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus. (605 citations)

What are the main themes of his work throughout his whole career to date?

Yanick J. Crow focuses on Immunology, Genetics, Aicardi–Goutières syndrome, Interferon and Pathology. His study in the fields of Innate immune system, Interferon type I and Autoimmunity under the domain of Immunology overlaps with other disciplines such as Sting. Mutation, Gene, Phenotype, Locus and Genetic heterogeneity are the core of his Genetics study.

His Missense mutation study, which is part of a larger body of work in Mutation, is frequently linked to Singleton Merten syndrome and Context, bridging the gap between disciplines. The various areas that he examines in his Aicardi–Goutières syndrome study include Aicardi syndrome, Encephalopathy and Alpha interferon. His Interferon study integrates concerns from other disciplines, such as Cancer research, Downregulation and upregulation, Janus kinase 1, Molecular biology and Cell biology.

He most often published in these fields:

  • Immunology (41.41%)
  • Genetics (34.64%)
  • Aicardi–Goutières syndrome (31.25%)

What were the highlights of his more recent work (between 2018-2021)?

  • Interferon (41.41%)
  • Immunology (41.41%)
  • Genetics (34.64%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Interferon, Immunology, Genetics, Aicardi–Goutières syndrome and Disease. His studies deal with areas such as Phenotype, Gene, Wild type and Stimulator of interferon genes as well as Interferon. His biological study spans a wide range of topics, including Molecular biology and Cell biology.

Yanick J. Crow interconnects Downregulation and upregulation and Lung injury in the investigation of issues within Immunology. His study on Genotype, Proband and Zebrafish is often connected to Ribosome biogenesis and RRNA processing as part of broader study in Genetics. His Aicardi–Goutières syndrome study incorporates themes from Failure to thrive, Alpha interferon, Bioinformatics and Immunodeficiency.

Between 2018 and 2021, his most popular works were:

  • Self-Awareness: Nucleic Acid-Driven Inflammation and the Type I Interferonopathies. (49 citations)
  • Self-Awareness: Nucleic Acid-Driven Inflammation and the Type I Interferonopathies. (49 citations)
  • Bloom syndrome protein restrains innate immune sensing of micronuclei by cGAS. (32 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Mutation
  • Internal medicine

Yanick J. Crow mostly deals with Interferon, Mutation, Sting, Immunology and Cell biology. His Interferon research is multidisciplinary, incorporating elements of STAT2, Transcription, stat, Transcription factor and Loss of heterozygosity. His Mutation study combines topics from a wide range of disciplines, such as Phenotype, Gene silencing, Golgi apparatus and Pathology.

Yanick J. Crow studies Aicardi–Goutières syndrome, a branch of Phenotype. Yanick J. Crow works on Immunology which deals in particular with Interferon-stimulated gene. The Cell biology study combines topics in areas such as Inflammation, HEK 293 cells, Protein subunit, Gene and Immune system.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

David C. Goldstone;Valerie Ennis-Adeniran;Joseph J. Hedden;Harriet C. T. Groom.
Nature (2011)

854 Citations

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus.

Yanick J Crow;Yanick J Crow;Bruce E Hayward;Rekha Parmar;Peter Robins.
Nature Genetics (2006)

807 Citations

International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity

Capucine Picard;H. Bobby Gaspar;Waleed Al-Herz;Aziz Bousfiha.
Journal of Clinical Immunology (2018)

727 Citations

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response.

Gillian I Rice;Jacquelyn Bond;Aruna Asipu;Rebecca L Brunette.
Nature Genetics (2009)

699 Citations

ASPM is a major determinant of cerebral cortical size.

Jacquelyn Bond;Emma Roberts;Ganesh H. Mochida;Ganesh H. Mochida;Daniel J. Hampshire.
Nature Genetics (2002)

692 Citations

Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection.

Yanick J Crow;Yanick J Crow;Andrea Leitch;Bruce E Hayward;Anna Garner.
Nature Genetics (2006)

679 Citations

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

Gillian I. Rice;Paul R. Kasher;Gabriella M A Forte;Niamh M. Mannion.
Nature Genetics (2012)

670 Citations

Large-scale discovery of novel genetic causes of developmental disorders

T.W. Fitzgerald;S.S. Gerety;W.D. Jones;M. van Kogelenberg.
Nature (2015)

661 Citations

Aicardi–Goutières syndrome and the type I interferonopathies

Yanick J. Crow;Nicolas Manel.
Nature Reviews Immunology (2015)

643 Citations

The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies.

Aziz Bousfiha;Leïla Jeddane;Capucine Picard;Fatima Ailal.
Journal of Clinical Immunology (2018)

518 Citations

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