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Biology and Biochemistry

D-Index
57
Citations
12317
World Ranking
13793
National Ranking
5836

Overview

Baek Kim is a researcher affiliated with Emory University in the United States with a focus on biochemistry, genetics, and molecular biology, alongside significant contributions in medicine. Their scholarly output reflects extensive work in molecular biology, infectious diseases, virology, epidemiology, and oncology.

Their recent publications include:

  • The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer, 2020, Nature Communications
  • Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase, 2021, Microorganisms
  • SAMHD1 Functions and Human Diseases, 2020, Viruses
  • Repurposing Nucleoside Analogs for Human Coronaviruses, 2020, Antimicrobial Agents and Chemotherapy
  • Ribonucleotide reductase inhibitors suppress SAMHD1 ara- CTP ase activity enhancing cytarabine efficacy, 2020, EMBO Molecular Medicine

Baek Kim frequently collaborates with several co-authors, including:

  • Raymond F. Schinazi
  • Adrian Oo
  • Nicole E. Bowen
  • Sijia Tao
  • Bijan Mahboubi

The researcher commonly publishes in the following venues:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • mBio
  • Journal of Biological Chemistry

The main fields of study for Baek Kim encompass biochemistry, genetics, and molecular biology with 76 publications, as well as medicine with 69 publications.

Subfields include:

  • Molecular Biology
  • Infectious Diseases
  • Virology
  • Epidemiology
  • Oncology

Key topics addressed in their work are:

  • HIV Research and Treatment
  • HIV/AIDS drug development and treatment
  • Cytomegalovirus and herpesvirus research
  • Interferon and immune responses
  • DNA Repair Mechanisms
  • Ubiquitin and proteasome pathways
  • Biochemical and Molecular Research

Best Publications

  • SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates.

    Hichem Lahouassa;Waaqo Daddacha;Henning Hofmann;Diana Ayinde;Diana Ayinde;Diana Ayinde

  • SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.

    Hanna Mari Baldauf;Xiaoyu Pan;Elina Erikson;Elina Erikson;Sarah Schmidt

  • Macrophage Tropism of HIV-1 Depends on Efficient Cellular dNTP Utilization by Reverse Transcriptase

    Tracy L. Diamond;Mikhail Roshal;Varuni K. Jamburuthugoda;Holly M. Reynolds

  • The Retroviral Restriction Ability of SAMHD1, but Not Its Deoxynucleotide Triphosphohydrolase Activity, Is Regulated by Phosphorylation

    Tommy E. White;Alberto Brandariz-Nuñez;Jose Carlos Valle-Casuso;Sarah Amie

  • The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

    Jeongmin Ryoo;Jongsu Choi;Changhoon Oh;Sungchul Kim

  • PB2 Residue 271 Plays a Key Role in Enhanced Polymerase Activity of Influenza A Viruses in Mammalian Host Cells

    Kendra A. Bussey;Tatiana L. Bousse;Emily A. Desmet;Baek Kim

  • Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R.

    Mikhail Roshal;Baek Kim;Yonghong Zhu;Paul Nghiem

  • Tight interplay among SAMHD1 protein level, cellular dNTP levels, and HIV-1 proviral DNA synthesis kinetics in human primary monocyte-derived macrophages.

    Baek Kim;Laura A. Nguyen;Waaqo Daddacha;Joseph A. Hollenbaugh

  • The Ambiguous Base-Pairing and High Substrate Efficiency of T-705 (Favipiravir) Ribofuranosyl 5′-Triphosphate towards Influenza A Virus Polymerase

    Zhinan Jin;Lucas K. Smith;Vivek K. Rajwanshi;Baek Kim

  • Host Factor SAMHD1 Restricts DNA Viruses in Non- Dividing Myeloid Cells

    Joseph A. Hollenbaugh;Peter Gee;Jonathon Baker;Michele B. Daly;Michele B. Daly

  • Mouse SAMHD1 Has Antiretroviral Activity and Suppresses a Spontaneous Cell-Intrinsic Antiviral Response.

    Raymond Behrendt;Tina Schumann;Alexander Gerbaulet;Laura A Nguyen

  • Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy.

    Pauline Chugh;Birgit Bradel-Tretheway;Carlos M R Monteiro-Filho;Vicente Planelles

  • The Vpx Lentiviral Accessory Protein Targets SAMHD1 for Degradation in the Nucleus

    Henning Hofmann;Eric C. Logue;Nicolin Bloch;Waaqo Daddacha

  • Restriction of diverse retroviruses by SAMHD1

    Thomas Gramberg;Tanja Kahle;Nicolin Bloch;Sabine Wittmann

  • SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.

    Waaqo Daddacha;Allyson E. Koyen;Amanda J. Bastien;Pamela Sara E. Head

  • Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1.

    Tommy E White;Alberto Brandariz-Nuñez;Jose Carlos Valle-Casuso;Sarah Amie

  • SAMHD1 prevents autoimmunity by maintaining genome stability

    Stefanie Kretschmer;Christine Wolf;Nadja König;Wolfgang Staroske

  • HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT.

    Joshua L Andersen;Jason L DeHart;Erik S Zimmerman;Orly Ardon

  • Metabolite profiles of human immunodeficiency virus infected CD4+ T cells and macrophages using LC-MS/MS analysis.

    Joseph A. Hollenbaugh;Joshua Munger;Baek Kim

  • PA Residues in the 2009 H1N1 Pandemic Influenza Virus Enhance Avian Influenza Virus Polymerase Activity in Mammalian Cells

    Kendra A. Bussey;Emily A. Desmet;Jonelle L. Mattiacio;Alice Hamilton

Frequent Co-Authors

Dong-Hyun Kim
Dong-Hyun Kim Kyung Hee University
Raymond F. Schinazi
Raymond F. Schinazi Emory University
Stephen Dewhurst
Stephen Dewhurst University of Rochester
Felipe Diaz-Griffero
Felipe Diaz-Griffero Albert Einstein College of Medicine
Robert A. Bambara
Robert A. Bambara University of Rochester
Raymond F. Schinazi
Raymond F. Schinazi Emory University
Gianfranco Pancino
Gianfranco Pancino Institut Pasteur
Li Wu
Li Wu University of Iowa
Oliver T. Keppler
Oliver T. Keppler Ludwig-Maximilians-Universität München

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