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Microbiology

D-Index
63
Citations
13611
World Ranking
2741
National Ranking
208

Overview

Oliver T. Keppler is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research primarily focuses on medicine, with significant contributions to subfields such as infectious diseases, molecular biology, immunology, epidemiology, and neurology.

The main topics of their work include:

  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 detection and testing
  • Long-Term Effects of COVID-19
  • HIV Research and Treatment
  • Immune Cell Function and Interaction
  • Cytomegalovirus and herpesvirus research

Key publications by Oliver T. Keppler include:

  • Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy, 2020, Circulation
  • Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern, 2022, Nature Medicine
  • Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19, 2021, Immunity
  • MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells, 2021, PLoS Genetics
  • CARD8 inflammasome activation triggers pyroptosis in human T cells, 2020, The EMBO Journal

Frequent collaborators include Maximilian Muenchhoff, Paul R. Wratil, Helmut Blum, Alexander Graf, and Marcel Stern.

Oliver T. Keppler's work has been published in a variety of scientific venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Medical Microbiology and Immunology
  • Infection
  • Nature Communications
  • Cell Reports

Best Publications

  • SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.

    Hanna Mari Baldauf;Xiaoyu Pan;Elina Erikson;Elina Erikson;Sarah Schmidt

  • Semen-Derived Amyloid Fibrils Drastically Enhance HIV Infection

    Jan Münch;Elke Rücker;Ludger Ständker;Knut Adermann

  • Biochemical engineering of the N-acyl side chain of sialic acid: biological implications.

    Oliver T. Keppler;Rüdiger Horstkorte;Michael Pawlita;Carolin Schmidt

  • Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy.

    Leo Nicolai;Alexander Leunig;Sophia Brambs;Rainer Kaiser

  • Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern

    Unknown

  • UDP-GlcNAc 2-Epimerase: A Regulator of Cell Surface Sialylation

    Oliver T. Keppler;Stephan Hinderlich;Josmar Langner;Reinhard Schwartz-Albiez

  • HIV-1 Buds Predominantly at the Plasma Membrane of Primary Human Macrophages

    Sonja Welsch;Oliver Till Keppler;Anja Habermann;Ina Allespach

  • MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells

    Unknown

  • HIV-1 antagonism of CD317 is species specific and involves Vpu-mediated proteasomal degradation of the restriction factor.

    Christine Goffinet;Ina Allespach;Stefanie Homann;Hanna-Mari Tervo

  • Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care

    Timo Wolf;Gerrit Kann;Stephan Becker;Christoph Stephan

  • Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides.

    Nuria Izquierdo-Useros;Maier Lorizate;Maria C. Puertas;Maria T. Rodriguez-Plata

  • Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.

    Benjamin Krämer;Rainer Knoll;Lorenzo Bonaguro;Michael ToVinh

  • The Nef protein of human immunodeficiency virus establishes superinfection immunity by a dual strategy to downregulate cell-surface CCR5 and CD4.

    Nico Michel;Ina Allespach;Stephanie Venzke;Oliver T. Fackler

  • Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020.

    Erik Alm;Eeva K Broberg;Thomas Connor;Emma B Hodcroft

  • Biosynthetic Modulation of Sialic Acid-dependent Virus-Receptor Interactions of Two Primate Polyoma Viruses

    Oliver T. Keppler;Peer Stehling;Markus Herrmann;Holger Kayser

  • Impaired detection of omicron by SARS-CoV-2 rapid antigen tests

    Unknown

  • The wide utility of rabbits as models of human diseases

    Pedro J. Esteves;Joana Abrantes;Hanna Mari Baldauf;Lbachir BenMohamed

  • Low vitamin D serum concentration is associated with high levels of hepatitis B virus replication in chronically infected patients

    Harald Farnik;Jörg Bojunga;Annemarie Berger;Regina Allwinn

  • CARD8 inflammasome activation triggers pyroptosis in human T cells

    Andreas Linder;Stefan Bauernfried;Yiming Cheng;Manuel Albanese

  • SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia

    Constanze Schneider;Thomas Oellerich;Hanna-Mari Baldauf;Hanna-Mari Baldauf;Sarah-Marie Schwarz

  • In vivo evolution of human immunodeficiency virus type 1 toward increased pathogenicity through CXCR4-mediated killing of uninfected CD4 T cells.

    Andreas Jekle;Oliver T. Keppler;Erik De Clercq;Dominique Schols

  • Sensory neuropathy in human immunodeficiency virus/acquired immunodeficiency syndrome patients: protease inhibitor-mediated neurotoxicity.

    Jacqueline A. Pettersen;Gareth Jones;Catherine Worthington;Hartmut B. Krentz

  • Restrictions to HIV-1 replication in resting CD4 + T lymphocytes

    Xiaoyu Pan;Hanna Mari Baldauf;Oliver T. Keppler;Oliver T. Fackler

  • Cell Cycle Control and HIV-1 Susceptibility Are Linked by CDK6-Dependent CDK2 Phosphorylation of SAMHD1 in Myeloid and Lymphoid Cells

    Eduardo Pauls;Alba Ruiz;Roger Badia;Marc Permanyer

  • HIV-1 Gag Processing Intermediates Trans-dominantly Interfere with HIV-1 Infectivity *

    Barbara Müller;Maria Anders;Hisashi Akiyama;Sonja Welsch;Sonja Welsch

Frequent Co-Authors

Oliver T. Fackler
Oliver T. Fackler University Hospital Heidelberg
Michael Pawlita
Michael Pawlita German Cancer Research Center
Werner Reutter
Werner Reutter Freie Universität Berlin
Annemarie Berger
Annemarie Berger Goethe University Frankfurt
Hans-Georg Kräusslich
Hans-Georg Kräusslich Heidelberg University
Mark A. Goldsmith
Mark A. Goldsmith Revolution Medicines
Javier Martinez-Picado
Javier Martinez-Picado University of Vic - Central University of Catalonia
Jindrich Cinatl
Jindrich Cinatl Goethe University Frankfurt
Veit Hornung
Veit Hornung Ludwig-Maximilians-Universität München
Gerd Geisslinger
Gerd Geisslinger Goethe University Frankfurt

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