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Biology and Biochemistry

D-Index
51
Citations
8357
World Ranking
17270
National Ranking
7104

Overview

Kevin J. Yarema is affiliated with Johns Hopkins University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions in medicine. They have published extensively in areas related to molecular biology, radiology, nuclear medicine and imaging, immunology, cell biology, and organic chemistry.

The main topics addressed in their work include:

  • Glycosylation and Glycoproteins Research
  • Monoclonal and Polyclonal Antibodies Research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Immunotherapy and Immune Responses
  • Ubiquitin and proteasome pathways
  • Biochemical and Molecular Research
  • Mitochondrial Function and Pathology

Kevin J. Yarema has published in several scientific venues, frequently contributing to:

  • Frontiers in Chemistry
  • Cells
  • Biomaterials Advances
  • Advanced Functional Materials
  • JCI Insight

Recent papers include:

  • "Strategies for Glycoengineering Therapeutic Proteins," 2022, Frontiers in Chemistry
  • "Improving the Pharmacodynamics and In Vivo Activity of ENPP1-Fc Through Protein and Glycosylation Engineering," 2020, Clinical and Translational Science
  • "A dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models," 2024, JCI Insight
  • "Glycoengineering Human Neural and Adipose Stem Cells with Novel Thiol-Modified N-Acetylmannosamine (ManNAc) Analogs," 2021, Cells
  • "Glycoengineering human neural stem cells (hNSCs) for adhesion improvement using a novel thiol-modified N-acetylmannosamine (ManNAc) analog," 2022, Biomaterials Advances

The scientist frequently collaborates with:

  • Kris Dammen-Brower
  • Christian Agatemor
  • Jian Du
  • Xiaofeng Jia
  • Paul R. Stabach

Best Publications

  • Engineering chemical reactivity on cell surfaces through oligosaccharide biosynthesis

    Lara K. Mahal;Kevin J. Yarema;Carolyn R. Bertozzi

  • Metabolic Glycoengineering: Sialic Acid and Beyond

    Jian Du;M Adam Meledeo;Zhiyun Wang;Hargun S Khanna

  • The effect of nanofiber-guided cell alignment on the preferential differentiation of neural stem cells.

    Shawn H. Lim;Xingyu Y. Liu;Xingyu Y. Liu;Hongjun Song;Kevin J. Yarema

  • Analysis of Incision Sites Produced by Human Cell Extracts and Purified Proteins during Nucleotide Excision Repair of a 1,3-Intrastrand d(GpTpG)-Cisplatin Adduct

    Jonathan G. Moggs;Kevin J. Yarema;John M. Essigmann;Richard D. Wood

  • Metabolic Delivery of Ketone Groups to Sialic Acid Residues APPLICATION TO CELL SURFACE GLYCOFORM ENGINEERING

    Kevin J. Yarema;Lara K. Mahal;Richard E. Bruehl;Elena C. Rodriguez

  • Chemical approaches to glycobiology and emerging carbohydrate-based therapeutic agents.

    Kevin J Yarema;Carolyn R Bertozzi

  • Substrate specificity of the sialic acid biosynthetic pathway

    Christina L. Jacobs;Scarlett Goon;Kevin J. Yarema;Stephan Hinderlich

  • An intrastrand d(GpG) platinum crosslink in duplex M13 DNA is refractory to repair by human cell extracts.

    David E. Szymkowski;Kevin Yarema;John M. Essigmann;Stephen J. Lippard

  • Exploiting differences in sialoside expression for selective targeting of MRI contrast reagents

    George A. Lemieux;Kevin J. Yarema;Christina L. Jacobs;Carolyn R. Bertozzi

  • Metabolic installation of thiols into sialic acid modulates adhesion and stem cell biology

    Srinivasa Gopalan Sampathkumar;Adrienne V. Li;Mark B. Jones;Zhonghui Sun

  • Glucosamine modulates chondrocyte proliferation, matrix synthesis, and gene expression

    S. Varghese;P. Theprungsirikul;S. Sahani;N. Hwang

  • Characterizing glycosylation pathways

    Kevin J Yarema;Kevin J Yarema;Carolyn R Bertozzi

  • Characterization of the cellular uptake and metabolic conversion of acetylated N-acetylmannosamine (ManNAc) analogues to sialic acids.

    Mark B. Jones;Howard Teng;Jun Kyu Rhee;Nicholas Lahar

  • Metabolic oligosaccharide engineering: perspectives, applications, and future directions.

    Christopher T. Campbell;Srinivasa Gopalan Sampathkumar;Kevin J. Yarema

  • Exploiting metabolic glycoengineering to advance healthcare.

    Christian Agatemor;Matthew J. Buettner;Ryan Ariss;Keerthana Muthiah

  • No overall hyposialylation in hereditary inclusion body myopathy myoblasts carrying the homozygous M712T GNE mutation.

    Ilan Salama;Stephan Hinderlich;Zipora Shlomai;Iris Eisenberg

  • Roles for UDP-GlcNAc 2-Epimerase/ManNAc 6-Kinase outside of Sialic Acid Biosynthesis MODULATION OF SIALYLTRANSFERASE AND BiP EXPRESSION, GM3 AND GD3 BIOSYNTHESIS, PROLIFERATION, AND APOPTOSIS, AND ERK1/2 PHOSPHORYLATION

    Zhiyun Wang;Zhonghui Sun;Adrienne V. Li;Kevin J. Yarema

  • Mutagenicity and genotoxicity of the major DNA adduct of the antitumor drug cis-diamminedichloroplatinum(II).

    Lisa J. N. Bradley;Kevin J. Yarema;Stephen J. Lippard;John M. Essigmann

  • Targeting Cancer Cells with Dendrimers

    Srinivasa Gopalan Sampathkumar;Kevin J. Yarema

  • GlcNAc 2-Epimerase Can Serve a Catabolic Role in Sialic Acid Metabolism

    Sarah J. Luchansky;Kevin J. Yarema;Saori Takahashi;Carolyn R. Bertozzi

Frequent Co-Authors

Carolyn R. Bertozzi
Carolyn R. Bertozzi Stanford University
Michael J. Betenbaugh
Michael J. Betenbaugh Johns Hopkins University
Hui Zhang
Hui Zhang Johns Hopkins University
Jennifer H. Elisseeff
Jennifer H. Elisseeff Johns Hopkins University
Werner Reutter
Werner Reutter Freie Universität Berlin
Andre Levchenko
Andre Levchenko Yale University
Kelley W. Moremen
Kelley W. Moremen University of Georgia
Chen-Zhong Li
Chen-Zhong Li Chinese University of Hong Kong, Shenzhen

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