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Christian P. R. Hackenberger

Christian P. R. Hackenberger

D-Index & Metrics

Chemistry

D-Index
44
Citations
7693
World Ranking
16782
National Ranking
1215

Overview

Christian P. R. Hackenberger is affiliated with Humboldt-Universität zu Berlin in Germany. Their research spans multiple disciplines including Biochemistry, Genetics and Molecular Biology, Medicine, and Chemistry, with a focus on various subfields such as Molecular Biology, Organic Chemistry, Radiology, Nuclear Medicine and Imaging, Oncology, and Materials Chemistry.

The primary topics covered in their work include:

  • Click Chemistry and Applications
  • Chemical Synthesis and Analysis
  • Monoclonal and Polyclonal Antibodies Research
  • Glycosylation and Glycoproteins Research
  • Virus-based gene therapy research
  • Advanced biosensing and bioanalysis techniques
  • Peptidase Inhibition and Analysis

Hackenberger has published extensively in a range of scientific journals. Frequent publication venues include:

  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Chemical Science
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Chemistry - A European Journal

Among their recent papers are:

  • Cellular uptake of large biomolecules enabled by cell-surface-reactive cell-penetrating peptide additives (2021, Nature Chemistry)
  • Recent advances of thiol-selective bioconjugation reactions (2020, Current Opinion in Chemical Biology)
  • Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry (2020, Nature Nanotechnology)
  • Chemically Induced Vinylphosphonothiolate Electrophiles for Thiol-Thiol Bioconjugations (2020, Journal of the American Chemical Society)
  • Diethynyl Phosphinates for Cysteine-Selective Protein Labeling and Disulfide Rebridging (2021, Angewandte Chemie International Edition)

Collaborations form a significant part of Hackenberger's research activities. Frequent co-authors include Christian E. Stieger, Jan Vincent V. Arafiles, Marc-André Kasper, Philipp Ochtrop, and Daniel Lauster, with multiple joint publications reflecting ongoing scientific partnerships.

Best Publications

  • Chemoselective Ligation and Modification Strategies for Peptides and Proteins

    Christian P. R. Hackenberger;Dirk Schwarzer

  • Covalent Attachment of Cyclic TAT Peptides to GFP Results in Protein Delivery into Live Cells with Immediate Bioavailability

    Nicole Nischan;Henry D. Herce;Henry D. Herce;Francesco Natale;Nina Bohlke

  • Nanobodies: Chemical Functionalization Strategies and Intracellular Applications.

    Dominik Schumacher;Dominik Schumacher;Jonas Helma;Anselm F. L. Schneider;Heinrich Leonhardt

  • Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells

    Henry D. Herce;Dominik Schumacher;Anselm F. L. Schneider;Anne K. Ludwig

  • Chemoselektive Ligations‐ und Modifikationsstrategien für Peptide und Proteine

    Christian P. R. Hackenberger;Dirk Schwarzer

  • Current Status: Site-Specific Antibody Drug Conjugates

    Dominik Schumacher;Christian P. R. Hackenberger;Heinrich Leonhardt;Jonas Helma

  • Cellular uptake of large biomolecules enabled by cell-surface-reactive cell-penetrating peptide additives.

    Anselm F. L. Schneider;Marina Kithil;M. Cristina Cardoso;Martin Lehmann

  • Recent advances of thiol-selective bioconjugation reactions.

    Philipp Ochtrop;Christian Peter Richard Hackenberger

  • Chemoselective peptide cyclization by traceless Staudinger ligation.

    Rolf Kleineweischede;Christian P. R. Hackenberger

  • An alkaloid-mediated desymmetrization of meso-anhydrides via a nucleophilic ring opening with benzyl alcohol and its application in the synthesis of highly enantiomerically enriched β-amino acids

    Carsten Bolm;Ingo Schiffers;Iuliana Atodiresei;Christian P.R. Hackenberger

  • Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation

    Caroline Smet-Nocca;Malgorzata Broncel;Jean-Michel Wieruszeski;Caroline Tokarski

  • Chemoselective Staudinger-phosphite reaction of azides for the phosphorylation of proteins.

    Remigiusz Serwa;Ina Wilkening;Giuseppe Del Signore;Michaela Mühlberg

  • Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry

    Daniel Lauster;Daniel Lauster;Simon Klenk;Kai Ludwig;Saba Nojoumi;Saba Nojoumi

  • Fluorescent labelling in living cells.

    Anselm Fabian Lowell Schneider;Christian Peter Richard Hackenberger;Christian Peter Richard Hackenberger

  • Versatile and Efficient Site-Specific Protein Functionalization by Tubulin Tyrosine Ligase

    Dominik Schumacher;Dominik Schumacher;Jonas Helma;Florian A. Mann;Florian A. Mann;Garwin Pichler

  • Site-specific PEGylation of proteins: recent developments.

    Nicole Nischan;Christian P. R. Hackenberger;Christian P. R. Hackenberger

  • Multivalent Peptide–Nanoparticle Conjugates for Influenza-Virus Inhibition

    Daniel Lauster;Maria Glanz;Maria Glanz;Markus Bardua;Kai Ludwig

  • Live-cell MRI with Xenon Hyper-CEST Biosensors Targeted to Metabolically Labeled Cell-Surface Glycans†

    Christopher Witte;Vera Martos;Honor May Rose;Stefan Reinke

  • More than add-on: chemoselective reactions for the synthesis of functional peptides and proteins.

    Dominik Schumacher;Christian P R Hackenberger

  • Cysteine-Selective Phosphonamidate Electrophiles for Modular Protein Bioconjugations

    Marc‐André Kasper;Maria Glanz;Andreas Stengl;Martin Penkert

  • Synthesis of phosphonamidate peptides by Staudinger reactions of silylated phosphinic acids and esters

    Ina Wilkening;Giuseppe del Signore;Christian P. R. Hackenberger

  • Synthetic and Spectroscopic Investigation of N-Acylated Sulfoximines†

    Christian P. R. Hackenberger;Gerhard Raabe;Carsten Bolm

Frequent Co-Authors

Heinrich Leonhardt
Heinrich Leonhardt Ludwig-Maximilians-Universität München
Carsten Bolm
Carsten Bolm RWTH Aachen University
M. Cristina Cardoso
M. Cristina Cardoso Technical University of Darmstadt
Peter Schmieder
Peter Schmieder Leibniz Institute for Neurobiology
Nediljko Budisa
Nediljko Budisa University of Manitoba
Dirk Schwarzer
Dirk Schwarzer Max Planck Society
Andreas Herrmann
Andreas Herrmann Humboldt-Universität zu Berlin
Rainer Haag
Rainer Haag Freie Universität Berlin
Christoph Böttcher
Christoph Böttcher Freie Universität Berlin

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