D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 84 Citations 29,623 280 World Ranking 526 National Ranking 39

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

Heinrich Leonhardt focuses on Molecular biology, Cell biology, DNA methylation, Chromatin and Control of chromosome duplication. His studies in Molecular biology integrate themes in fields like Replication protein A, DNA damage, DNA methyltransferase and DNA repair. In his research, Chromosome instability, Chromosome 15, DNA hypomethylation, Carcinogenesis and Gene rearrangement is intimately related to DNMT1, which falls under the overarching field of DNA methyltransferase.

Heinrich Leonhardt has researched Cell biology in several fields, including Antibody, Fluorescence, DNA and Green fluorescent protein. The concepts of his DNA methylation study are interwoven with issues in Histone and Epigenetics. Heinrich Leonhardt has included themes like Fluorescence recovery after photobleaching, Photobleaching and Propidium iodide in his Chromatin study.

His most cited work include:

  • Induction of tumors in mice by genomic hypomethylation. (1275 citations)
  • Induction of tumors in mice by genomic hypomethylation. (1275 citations)
  • A guide to super-resolution fluorescence microscopy (911 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Cell biology, Molecular biology, Chromatin, DNA methylation and Biochemistry. His Cell biology research integrates issues from DNA damage, DNA, DNA repair, Proliferating cell nuclear antigen and DNA replication. His study in the field of Eukaryotic DNA replication also crosses realms of DNA polymerase delta.

His study in Molecular biology is interdisciplinary in nature, drawing from both Cell, Cellular differentiation, Antigen, Cell nucleus and Gene isoform. His Chromatin study combines topics from a wide range of disciplines, such as Biophysics and Histone. His DNA methylation research includes elements of Methylation and Epigenetics.

He most often published in these fields:

  • Cell biology (49.53%)
  • Molecular biology (36.14%)
  • Chromatin (22.43%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cell biology (49.53%)
  • Chromatin (22.43%)
  • Computational biology (8.10%)

In recent papers he was focusing on the following fields of study:

Heinrich Leonhardt spends much of his time researching Cell biology, Chromatin, Computational biology, DNA and Biophysics. His Cell biology research incorporates themes from RNA, DNA repair, Gene silencing, Epigenetics and XIST. Heinrich Leonhardt has included themes like Chromosome, Nucleus and Compartmentalization in his Chromatin study.

DNA is a subfield of Biochemistry that he tackles. His research integrates issues of Wild type, Regulation of gene expression, MHC class I and Molecular biology in his study of Gene expression. His research in DNA methylation is mostly concerned with DNA hypomethylation.

Between 2018 and 2021, his most popular works were:

  • Heterochromatin drives compartmentalization of inverted and conventional nuclei (174 citations)
  • BigStitcher: reconstructing high-resolution image datasets of cleared and expanded samples. (70 citations)
  • Front Cover: N‐Hydroxysuccinimide‐Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates (ChemBioChem 1‐2/2020) (27 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

The scientist’s investigation covers issues in Cell biology, Computational biology, Chromatin, Genome and Transcription. His Cell biology research is multidisciplinary, incorporating perspectives in Ubiquitin, Multicellular organism and DNA repair. His research in Ubiquitin intersects with topics in Histone H3, DNA hypomethylation, DNMT1, DNA methylation and Phenotype.

Chromatin is closely attributed to Nucleolus in his research. The Genome study which covers Heterochromatin that intersects with DNA replication, DNA synthesis, Compartment and Proliferating cell nuclear antigen. His studies deal with areas such as Plasmid, DNA and Gene expression as well as Transcription.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Induction of tumors in mice by genomic hypomethylation.

François Gaudet;J. Graeme Hodgson;Amir Eden;Laurie Jackson-Grusby.
Science (2003)

1716 Citations

A guide to super-resolution fluorescence microscopy

Lothar Schermelleh;Rainer Heintzmann;Rainer Heintzmann;Heinrich Leonhardt.
Journal of Cell Biology (2010)

1434 Citations

A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

Heinrich Leonhardt;Andrea W. Page;Heinz-Ulrich Weier;Timothy H. Bestor.
Cell (1992)

1306 Citations

Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy

Lothar Schermelleh;Peter M. Carlton;Sebastian Haase;Lin Shao.
Science (2008)

1151 Citations

Comparative Analysis of Single-Cell RNA Sequencing Methods.

Christoph Ziegenhain;Beate I.H. Vieth;Swati Parekh;Björn Reinius.
Molecular Cell (2017)

987 Citations

Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

Cornelia G. Spruijt;Felix Gnerlich;Arne H. Smits;Toni Pfaffeneder.
Cell (2013)

945 Citations

A Versatile Nanotrap for Biochemical and Functional Studies with Fluorescent Fusion Proteins

Ulrich Rothbauer;Kourosh Zolghadr;Serge Muyldermans;Aloys Schepers.
Molecular & Cellular Proteomics (2008)

709 Citations

LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

Irina Solovei;Audrey S. Wang;Katharina Thanisch;Christine S. Schmidt.
Cell (2013)

681 Citations

Targeting and tracing antigens in live cells with fluorescent nanobodies

Ulrich Rothbauer;Kourosh Zolghadr;Sergey Tillib;Danny Nowak.
Nature Methods (2006)

669 Citations

Dynamics of DNA replication factories in living cells.

Heinrich Leonhardt;Hans-Peter Rahn;Peter Weinzierl;Anje Sporbert.
Journal of Cell Biology (2000)

640 Citations

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