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Genetics and Molecular Biology
Germany
2024

D-Index & Metrics

Molecular Biology

D-Index
94
Citations
37862
World Ranking
649
National Ranking
54

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Germany Leader Award

Overview

Heinrich Leonhardt is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research output is focused primarily on the field of Biochemistry, Genetics, and Molecular Biology, with a strong emphasis on Molecular Biology. Other subfields represented in their body of work include Immunology, Oncology, Genetics, and Organic Chemistry.

The scientist's research topics include:

  • Genomics and Chromatin Dynamics
  • RNA Research and Splicing
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Advanced biosensing and bioanalysis techniques
  • Cancer-related gene regulation

Leonhardt's recent publications, demonstrating a range of collaborative efforts, include:

  • "A protein assembly mediates Xist localization and gene silencing," 2020, Nature
  • "FUS-dependent liquid-liquid phase separation is important for DNA repair initiation," 2021, The Journal of Cell Biology
  • "Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation," 2020, Nature Communications
  • "Spatial organization of transcribed eukaryotic genes," 2022, Nature Cell Biology
  • "IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network," 2022, Immunity

The venues in which this scientist frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nucleic Acids Research
  • Blood
  • Nucleus

Frequent coauthors who have collaborated with Heinrich Leonhardt are:

  • Hartmann Harz
  • M. Cristina Cardoso
  • Sebastian Bultmann
  • Enes Ugur
  • Weihua Qin

Best Publications

  • Induction of tumors in mice by genomic hypomethylation.

    François Gaudet;J. Graeme Hodgson;Amir Eden;Laurie Jackson-Grusby

  • A guide to super-resolution fluorescence microscopy

    Lothar Schermelleh;Rainer Heintzmann;Rainer Heintzmann;Heinrich Leonhardt

  • Comparative Analysis of Single-Cell RNA Sequencing Methods.

    Christoph Ziegenhain;Beate I.H. Vieth;Swati Parekh;Björn Reinius

  • A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

    Heinrich Leonhardt;Andrea W. Page;Heinz-Ulrich Weier;Timothy H. Bestor

  • Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy

    Lothar Schermelleh;Peter M. Carlton;Sebastian Haase;Lin Shao

  • Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

    Cornelia G. Spruijt;Felix Gnerlich;Arne H. Smits;Toni Pfaffeneder

  • LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

    Irina Solovei;Audrey S. Wang;Katharina Thanisch;Christine S. Schmidt

  • A Versatile Nanotrap for Biochemical and Functional Studies with Fluorescent Fusion Proteins

    Ulrich Rothbauer;Kourosh Zolghadr;Serge Muyldermans;Aloys Schepers

  • Targeting and tracing antigens in live cells with fluorescent nanobodies

    Ulrich Rothbauer;Kourosh Zolghadr;Sergey Tillib;Danny Nowak

  • Dynamics of DNA replication factories in living cells.

    Heinrich Leonhardt;Hans-Peter Rahn;Peter Weinzierl;Anje Sporbert

  • Camelid immunoglobulins and nanobody technology.

    S. Muyldermans;T.N. Baral;V. Cortez Retamozzo;P. De Baetselier

  • Modulation of protein properties in living cells using nanobodies

    Axel Kirchhofer;Jonas Helma;Jonas Helma;Katrin Schmidthals;Katrin Schmidthals;Carina Frauer;Carina Frauer

  • Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes

    Laura Trinkle-Mulcahy;Séverine Boulon;Yun Wah Lam;Roby Urcia

  • Heterochromatin drives compartmentalization of inverted and conventional nuclei

    Martin Falk;Yana Feodorova;Yana Feodorova;Natalia Naumova;Maxim Imakaev

  • Cortical Constriction During Abscission Involves Helices of ESCRT-III–Dependent Filaments

    Julien Guizetti;Julien Guizetti;Lothar Schermelleh;Jana Mäntler;Sandra Maar

  • Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA

    Aleksandra Szwagierczak;Sebastian Bultmann;Christine S. Schmidt;Fabio Spada

  • Reversal of terminal differentiation and control of DNA replication: Cyclin A and cdk2 specifically localize at subnuclear sites of DNA replication

    M.Cristina Cardoso;M.Cristina Cardoso;Heinrich Leonhardt;Heinrich Leonhardt;Bernardo Nadal-Ginard;Bernardo Nadal-Ginard

  • In vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases

    Julia Arand;David Spieler;Tommy Karius;Miguel R. Branco;Miguel R. Branco

  • cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders

    Liudmila Andreeva;Björn Hiller;Dirk Kostrewa;Charlotte Lässig

  • Recruitment of DNA methyltransferase I to DNA repair sites.

    Oliver Mortusewicz;Lothar Schermelleh;Joachim Walter;M. Cristina Cardoso

Frequent Co-Authors

M. Cristina Cardoso
M. Cristina Cardoso Technical University of Darmstadt
Lothar Schermelleh
Lothar Schermelleh University of Oxford
Christian P. R. Hackenberger
Christian P. R. Hackenberger Humboldt-Universität zu Berlin
Thomas Cremer
Thomas Cremer Ludwig-Maximilians-Universität München
Serge Muyldermans
Serge Muyldermans Vrije Universiteit Brussel
Wolfgang Hiddemann
Wolfgang Hiddemann Ludwig-Maximilians-Universität München
Thomas Carell
Thomas Carell Ludwig-Maximilians-Universität München
Karl-Peter Hopfner
Karl-Peter Hopfner Ludwig-Maximilians-Universität München
Elisabeth Kremmer
Elisabeth Kremmer Max Planck Society
Thomas Bein
Thomas Bein Ludwig-Maximilians-Universität München

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