What is he best known for?
The fields of study he is best known for:
Karl-Peter Hopfner mainly focuses on Biochemistry, DNA, Protein structure, Cell biology and Molecular biology.
His studies in DNA integrate themes in fields like ATPase, Biophysics and Cyclic GMP-AMP synthase, Stimulator of interferon genes.
His Protein structure research includes themes of Plasma protein binding, Cyclase activity, Histone octamer, DNA repair and Antibody.
His study in Cell biology is interdisciplinary in nature, drawing from both Interferon and Base pair.
He has researched Molecular biology in several fields, including Epitope, Primary and secondary antibodies, Antigen, Signal transduction and Monoclonal antibody.
His biological study spans a wide range of topics, including Nucleic acid and Pattern recognition receptor.
His most cited work include:
- Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily. (821 citations)
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING (688 citations)
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING (688 citations)
What are the main themes of his work throughout his whole career to date?
Karl-Peter Hopfner focuses on Cell biology, DNA, Biochemistry, RNA and Genetics.
The study incorporates disciplines such as ATP hydrolysis, Molecular biology, Protein structure, Innate immune system and Binding site in addition to Cell biology.
His studies deal with areas such as Mutation, Signal transduction, Antibody and Transcription factor as well as Molecular biology.
His DNA research is multidisciplinary, incorporating perspectives in Biophysics and Rad50.
His research investigates the link between Biophysics and topics such as ATPase that cross with problems in Adenosine triphosphate, Hydrolase and Structural biology.
His work on Active site, Enzyme and Plasma protein binding as part of his general Biochemistry study is frequently connected to DNA clamp, thereby bridging the divide between different branches of science.
He most often published in these fields:
- Cell biology (40.00%)
- DNA (36.33%)
- Biochemistry (28.98%)
What were the highlights of his more recent work (between 2016-2021)?
- DNA (36.33%)
- Cell biology (40.00%)
- Cancer research (9.39%)
In recent papers he was focusing on the following fields of study:
Karl-Peter Hopfner mostly deals with DNA, Cell biology, Cancer research, Chromatin and Nucleosome.
His DNA research is included under the broader classification of Biochemistry.
His Cell biology research integrates issues from Protein structure, Innate immune system, DNA repair and DNA-binding protein.
His Innate immune system research is multidisciplinary, incorporating elements of RNA, Endogeny and Function.
As part of one scientific family, he deals mainly with the area of Chromatin, narrowing it down to issues related to the Microbial DNA, and often MAPK/ERK pathway, Signal transduction, Stimulator of interferon genes and ATP synthase.
His work carried out in the field of Nucleosome brings together such families of science as Genome, Computational biology and Chromatin remodeling.
Between 2016 and 2021, his most popular works were:
- cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders (150 citations)
- cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders (150 citations)
- Structural basis for ATP-dependent chromatin remodelling by the INO80 complex. (105 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Cell biology, DNA, Chromatin, RNA and RIG-I.
Karl-Peter Hopfner combines subjects such as Protein structure, Innate immune system, DNA repair and DNA-binding protein with his study of Cell biology.
His research in DNA intersects with topics in Biophysics and Rad50.
His work deals with themes such as Gene expression, Virus, Herpes simplex virus, Virology and Ribosomal RNA, which intersect with RNA.
He has included themes like Influenza A virus and Gene silencing in his RIG-I study.
Base pair is a subfield of Biochemistry that Karl-Peter Hopfner tackles.
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