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Immunology

D-Index
114
Citations
43959
World Ranking
416
National Ranking
255

Overview

Michael C. Carroll is affiliated with Boston Children's Hospital in the United States. Their research primarily lies within the fields of Immunology and Microbiology, with a significant body of work also contributing to Medicine. The focus extends to several specialized subfields, including Immunology, Rheumatology, Neurology, Molecular Biology, and Radiology, Nuclear Medicine and Imaging.

The scientist's work covers main topics such as T-cell and B-cell Immunology, Systemic Lupus Erythematosus Research, Immune Cell Function and Interaction, Neuroinflammation and Neurodegeneration Mechanisms, Complement system in diseases, Immunotherapy and Immune Responses, and Atherosclerosis and Cardiovascular Diseases.

Frequent publication venues for their research include The Journal of Immunology, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Alzheimer's & Dementia, and Brain Behavior and Immunity.

Michael C. Carroll has collaborated on multiple occasions with several colleagues. Notable frequent co-authors are Carlos Castrillón, Elliot H. Akama-Garren, Minghe Ma, Esra Yalçın, and Ernest Aw.

Representative recent publications highlight the scope of their research contributions:

  • Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice, 2020, Nature Neuroscience
  • Microglial responses to peripheral type 1 interferon, 2020, Journal of Neuroinflammation
  • Antigen presentation by B cells enables epitope spreading across an MHC barrier, 2023, Nature Communications
  • Follicular T cells are clonally and transcriptionally distinct in B cell-driven mouse autoimmune disease, 2021, Nature Communications
  • Complement C4A Regulates Autoreactive B Cells in Murine Lupus, 2020, Cell Reports

Best Publications

  • Schizophrenia risk from complex variation of complement component 4

    Aswin Sekar;Aswin Sekar;Allison R. Bialas;Heather de Rivera;Heather de Rivera;Avery Davis;Avery Davis

  • The complement system in regulation of adaptive immunity.

    Michael C Carroll

  • Bacteria activate sensory neurons that modulate pain and inflammation

    Isaac M. Chiu;Balthasar A. Heesters;Balthasar A. Heesters;Nader Ghasemlou;Christian A. Von Hehn

  • A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo.

    Philip R. Taylor;Anna Carugati;Valerie A. Fadok;H. Terence Cook

  • Arthritis Critically Dependent on Innate Immune System Players

    Hong Ji;Koichiro Ohmura;Koichiro Ohmura;Umar Mahmood;David M Lee

  • THE ROLE OF COMPLEMENT AND COMPLEMENT RECEPTORS IN INDUCTION AND REGULATION OF IMMUNITY

    Michael C. Carroll

  • A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model

    Isaac M. Chiu;Emiko T.A. Morimoto;Hani Goodarzi;Jennifer T. Liao

  • B cell receptor signal strength determines B cell fate.

    Stefano Casola;Stefano Casola;Kevin L Otipoby;Marat Alimzhanov;Sibille Humme;Sibille Humme

  • A Critical Role of Natural Immunoglobulin M in Immediate Defense Against Systemic Bacterial Infection

    Marianne Boes;Andrey P. Prodeus;Tara Schmidt;Michael C. Carroll

  • Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex.

    Douglas T. Fearon;Michael C. Carroll

  • Disruption of the Cr2 Locus Results in a Reduction in B-1a Cells and in an Impaired B Cell Response to T-Dependent Antigen

    Joseph M Ahearn;Michael B Fischer;Denise Croix;Siegfried Goerg

  • Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity

    Michael R. Wessels;Peter Butko;Minghe Ma;Henry B. Warren

  • Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation

    Anneli Peters;Lisa A. Pitcher;Jenna M. Sullivan;Meike Mitsdoerffer

  • Conduits Mediate Transport of Low-Molecular-Weight Antigen to Lymph Node Follicles

    Ramon Roozendaal;Thorsten R. Mempel;Lisa A. Pitcher;Santiago F. Gonzalez

  • Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks

    Deepali Malhotra;Anne L Fletcher;Jillian Astarita;Veronika Lukacs-Kornek

  • A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B

    Michael C. Carroll;R. Duncan Campbell;David R. Bentley;Rodney R. Porter

  • Regulation of Humoral Immunity by Complement

    Michael C. Carroll;David E. Isenman

  • The structural basis of the multiple forms of human complement component C4

    K T Belt;M C Carroll;R R Porter

  • Follicular dendritic cells: dynamic antigen libraries

    Balthasar A. Heesters;Riley C. Myers;Michael C. Carroll

  • Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice

    Ethel R. Pereira;Dmitriy Kedrin;Giorgio Seano;Olivia Gautier;Olivia Gautier

  • Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes

    Michael C. Carroll;Philip Katzman;Elizabeth M. Alicot;Beverly H. Koller

  • Mapping of steroid 21-hydroxylase genes adjacent to complement component C4 genes in HLA, the major histocompatibility complex in man.

    M C Carroll;R D Campbell;R R Porter

  • The Follicular versus Marginal Zone B Lymphocyte Cell Fate Decision Is Regulated by Aiolos, Btk, and CD21

    Annaiah Cariappa;Mei Tang;Chuenlei Parng;Eugene Nebelitskiy

  • A Critical Role for Complement in Maintenance of Self-Tolerance

    Andrey P Prodeus;Siegfried Goerg;Li-Ming Shen;Olga O Pozdnyakova

Frequent Co-Authors

M. Pripstein
M. Pripstein University of California, Berkeley
B. Foster
B. Foster Deutsches Elektronen-Synchrotron DESY
T. Schalk
T. Schalk University of California, Santa Cruz
B. N. Ratcliff
B. N. Ratcliff Stanford University
R. Waldi
R. Waldi University of Rostock

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