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Immunology

D-Index
104
Citations
34812
World Ranking
623
National Ranking
363

Medicine

D-Index
104
Citations
34888
World Ranking
7116
National Ranking
3738

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

V. Michael Holers is affiliated with the University of Colorado Denver in the United States. Their research focuses primarily on Medicine, with significant contributions in Immunology and Microbiology. Subfields of study include Rheumatology, Immunology, Radiology, Nuclear Medicine and Imaging, Hematology, and Nephrology.

The scientist's work covers a range of topics, including:

  • Systemic Lupus Erythematosus Research
  • Rheumatoid Arthritis Research and Therapies
  • Complement system in diseases
  • Monoclonal and Polyclonal Antibodies Research
  • T-cell and B-cell Immunology
  • Renal Diseases and Glomerulopathies
  • Autoimmune and Inflammatory Disorders Research

V. Michael Holers has published in multiple venues with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Arthritis & Rheumatology
  • The Journal of Immunology
  • Annals of the Rheumatic Diseases
  • Frontiers in Immunology

Notable recent papers include:

  • Notch signalling drives synovial fibroblast identity and arthritis pathology (2020, Nature)
  • Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes (2023, Nature)
  • Rheumatoid Arthritis Pathogenesis, Prediction, and Prevention: An Emerging Paradigm Shift (2020, Arthritis & Rheumatology)
  • Methotrexate and rheumatoid arthritis associated interstitial lung disease (2020, European Respiratory Journal)
  • Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum (2022, Science Translational Medicine)

Frequent co-authors in their work include:

  • Kevin D. Deane
  • Jennifer Seifert
  • Larry W. Moreland
  • Gary S. Firestein
  • Jane H. Buckner

V. Michael Holers has been recognized as a Member of the Association of American Physicians.

Best Publications

  • Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.

    Fan Zhang;Kevin Wei;Kamil Slowikowski;Chamith Y Fonseka

  • Arthritis Critically Dependent on Innate Immune System Players

    Hong Ji;Koichiro Ohmura;Koichiro Ohmura;Umar Mahmood;David M Lee

  • Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome

    Guillermina Girardi;Jessica Berman;Patricia Redecha;Lynn Spruce

  • Complement C3 activation is required for antiphospholipid antibody-induced fetal loss.

    V. Michael Holers;Guillermina Girardi;Lian Mo;Joel M. Guthridge

  • C3 glomerulopathy: consensus report

    Matthew C. Pickering;Vivette D. D'agati;Carla M. Nester;Richard J. Smith

  • Genetic and environmental risk factors for rheumatoid arthritis

    Kevin D. Deane;M. Kristen Demoruelle;Lindsay B. Kelmenson;Kristine A. Kuhn

  • Identification of a central role for complement in osteoarthritis

    Qian Wang;Andrew L Rozelle;Christin M Lepus;Carla R Scanzello

  • Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis

    Kristine A. Kuhn;Liudmila Kulik;Beren Tomooka;Kristin J. Braschler

  • A Critical Role for Murine Complement Regulator Crry in Fetomaternal Tolerance

    Chenguang Xu;Dailing Mao;V. Michael Holers;Ben Palanca

  • The central role of the alternative complement pathway in human disease.

    Joshua M. Thurman;V. Michael Holers

  • Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction

    Guillermina Girardi;Dmitry Yarilin;Joshua M. Thurman;V. Michael Holers

  • Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo

    Fangfang Chen;Fangfang Chen;Guankui Wang;James I. Griffin;Barbara Brenneman

  • Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis.

    Jeremy Sokolove;Jeremy Sokolove;Reuven Bromberg;Reuven Bromberg;Kevin D. Deane;Lauren J. Lahey

  • Complement and Its Receptors: New Insights into Human Disease

    V Michael Holers

  • Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction.

    V. Michael Holers;M. Kristen Demoruelle;Kristine A. Kuhn;Jane H. Buckner

  • REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

    Peter K Gregersen;Chistopher I Amos;Annette T Lee;Yue Lu

  • Lack of a Functional Alternative Complement Pathway Ameliorates Ischemic Acute Renal Failure in Mice

    Joshua M. Thurman;Danica Ljubanovic;Charles L. Edelstein;Gary S. Gilkeson

  • Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis

    Ted R. Mikuls;Jeffrey B. Payne;Richard A. Reinhardt;Geoffrey M. Thiele

  • The spectrum of complement alternative pathway‐mediated diseases

    V. Michael Holers

  • N-α-Benzoyl-N5-(2-Chloro-1-Iminoethyl)-l-Ornithine Amide, a Protein Arginine Deiminase Inhibitor, Reduces the Severity of Murine Collagen-Induced Arthritis

    Van C. Willis;Alison M. Gizinski;Nirmal K. Banda;Corey P. Causey

Frequent Co-Authors

Jill M. Norris
Jill M. Norris University of Colorado Anschutz Medical Campus
Stephen Tomlinson
Stephen Tomlinson Medical University of South Carolina
William H. Robinson
William H. Robinson Stanford University
Richard J. Quigg
Richard J. Quigg University at Buffalo, State University of New York
William P. Arend
William P. Arend University of Colorado Denver
Michael H. Weisman
Michael H. Weisman Cedars-Sinai Medical Center
Kazue Takahashi
Kazue Takahashi Harvard University
Jane H. Buckner
Jane H. Buckner Virginia Mason Medical Center
Peter K. Gregersen
Peter K. Gregersen Feinstein Institute for Medical Research
Jane E. Salmon
Jane E. Salmon Hospital for Special Surgery

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Related Online Degrees & Career Pathways

For those interested in Immunology, exploring related healthcare fields can open diverse career opportunities. Many professionals transition into nursing and advanced practice roles, which are closely aligned with immunological knowledge. One popular route is through an accelerated NP program, designed to fast-track registered nurses into nurse practitioner roles, combining clinical expertise with specialized skills.

If you are new to healthcare, consider enrolling in online BSN programs for non nurses. These programs provide foundational nursing education and prepare students for a range of medical fields, including immunology support roles. For faster entry, some students opt for the easiest accelerated nursing programs, which offer more accessible admission criteria without compromising educational quality.

Additionally, practical nursing is another viable option. Schools often offer easy admission LPN programs, providing quick pathways into the workforce and a solid base for those who might later pursue advanced immunology or nursing credentials.

Strategically choosing these educational pathways can help build a versatile career in healthcare, blending immunology with practical skills for enhanced patient care and research opportunities.

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