World's Best Scientists 2026 revealed!
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René E. M. Toes
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Immunology
Netherlands
2026
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Medicine
Netherlands
2023

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Immunology 124 297 275 10 10 568 59635
Medicine 124 3212 2999 118 116 573 59635

René E. M. Toes publications per year

The chart shows the history of publications by René E. M. Toes between 1992 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. René E. M. Toes published across 34 years, from 1992 to 2025, averaging 20 papers a year. Output peaked at 50 publications in 2013. 65 of the 679 publications appeared in the last two years.

No. of publications
10 20 30 40 50
Bar chart. Horizontal axis: year, 1992 to 2025. Vertical axis: number of publications, 0 to 50. Peak 50 publications in 2013. 1992: 1 publication 1993: 2 publications 1994: 1 publication 1995: 3 publications 1996: 6 publications 1997: 3 publications 1998: 5 publications 1999: 9 publications 2000: 13 publications 2001: 9 publications 2002: 7 publications 2003: 14 publications 2004: 18 publications 2005: 18 publications 2006: 22 publications 2007: 24 publications 2008: 19 publications 2009: 21 publications 2010: 26 publications 2011: 42 publications 2012: 34 publications 2013: 50 publications 2014: 31 publications 2015: 39 publications 2016: 33 publications 2017: 37 publications 2018: 28 publications 2019: 25 publications 2020: 12 publications 2021: 11 publications 2022: 26 publications 2023: 25 publications 2024: 29 publications 2025: 36 publications
1992 2025

679 publications in total across all disciplines

View publications per year as a table
René E. M. Toes: publications per year, 1992 to 2025
Year Publications
1992 1
1993 2
1994 1
1995 3
1996 6
1997 3
1998 5
1999 9
2000 13
2001 9
2002 7
2003 14
2004 18
2005 18
2006 22
2007 24
2008 19
2009 21
2010 26
2011 42
2012 34
2013 50
2014 31
2015 39
2016 33
2017 37
2018 28
2019 25
2020 12
2021 11
2022 26
2023 25
2024 29
2025 36
Total 679
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René E. M. Toes publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where René E. M. Toes sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 76 bars. Horizontal axis: publications, 62–71 to 807+. Vertical axis: number of scientists, 0 to 189. Most scientists, 189, have 152–161 publications. The last bar groups every scientist with 807 publications or more. The highlighted bar, 562–571 publications, is where this scientist sits. 62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientist 807+ publications: 100 scientists
62–71 publications 807+

This scientist: 568 publications — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

View publications distribution as a table
Number of Immunology scientists by publication count, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
Publications Scientists This scientist
62–71 9
72–81 23
82–91 40
92–101 72
102–111 86
112–121 108
122–131 150
132–141 160
142–151 159
152–161 189
162–171 166
172–181 181
182–191 188
192–201 187
202–211 178
212–221 158
222–231 168
232–241 159
242–251 160
252–261 148
262–271 116
272–281 125
282–291 115
292–301 111
302–311 95
312–321 97
322–331 97
332–341 99
342–351 96
352–361 69
362–371 76
372–381 71
382–391 71
392–401 62
402–411 54
412–421 41
422–431 63
432–441 53
442–451 31
452–461 42
462–471 40
472–481 29
482–491 34
492–501 30
502–511 23
512–521 41
522–531 29
532–541 28
542–551 16
552–561 18
562–571 18 568
572–581 17
582–591 17
592–601 17
602–611 19
612–621 13
622–631 12
632–641 11
642–651 16
652–661 9
662–671 5
672–681 13
682–691 12
692–701 6
702–711 6
712–721 9
722–731 9
732–741 6
742–751 11
752–761 10
762–771 7
772–781 12
782–791 7
792–801 5
802–806 1
807+ 100
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René E. M. Toes D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where René E. M. Toes sits on this spectrum.

No. of scientists
50 100 150 200
Bar chart with 60 bars. Horizontal axis: D-Index, 40–41 to 157+. Vertical axis: number of scientists, 0 to 201. Most scientists, 201, have 58–59 D-Index. The last bar groups every scientist with 157 D-Index or more. The highlighted bar, 124–125 D-Index, is where this scientist sits. 40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40–41 D-Index 157+

This scientist: 124 D-Index — 94th percentile

94% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

View D-Index distribution as a table
Number of Immunology scientists by D-index, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
D-Index Scientists This scientist
40–41 28
42–43 91
44–45 157
46–47 192
48–49 175
50–51 188
52–53 177
54–55 155
56–57 194
58–59 201
60–61 197
62–63 201
64–65 173
66–67 167
68–69 172
70–71 199
72–73 184
74–75 133
76–77 163
78–79 127
80–81 121
82–83 125
84–85 121
86–87 102
88–89 96
90–91 75
92–93 72
94–95 74
96–97 66
98–99 68
100–101 49
102–103 60
104–105 54
106–107 36
108–109 23
110–111 52
112–113 41
114–115 34
116–117 25
118–119 28
120–121 11
122–123 20
124–125 27 124
126–127 19
128–129 20
130–131 16
132–133 17
134–135 14
136–137 15
138–139 9
140–141 11
142–143 9
144–145 9
146–147 7
148–149 7
150–151 7
152–153 5
154–155 8
156 6
157+ 96
Download as CSV

Research.com Recognitions

  • 2026 - Research.com Immunology in Netherlands Leader Award
  • 2025 - Research.com Immunology in Netherlands Leader Award
  • 2023 - Research.com Medicine in Netherlands Leader Award
  • 2022 - Research.com Immunology in Netherlands Leader Award

Overview

René E. M. Toes is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a notable focus on several specialized subfields.

The main areas of study for René E. M. Toes include:

  • Medicine
  • Immunology and Microbiology

The scientist's work covers important subfields such as:

  • Rheumatology
  • Immunology
  • Radiology, Nuclear Medicine and Imaging
  • Pathology and Forensic Medicine
  • Molecular Biology

The primary research topics addressed by René E. M. Toes involve:

  • Monoclonal and Polyclonal Antibodies Research
  • Systemic Lupus Erythematosus Research
  • Rheumatoid Arthritis Research and Therapies
  • T-cell and B-cell Immunology
  • Systemic Sclerosis and Related Diseases
  • Glycosylation and Glycoproteins Research
  • Autoimmune Bullous Skin Diseases

René E. M. Toes has contributed extensively to scientific literature, publishing in several respected venues. The most frequent publication venues include:

  • Annals of the Rheumatic Diseases
  • RMD Open
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Arthritis Research & Therapy
  • Arthritis & Rheumatology

Several recent papers authored or co-authored by René E. M. Toes highlight ongoing contributions to immunology and autoimmune disease research:

  • Neutrophil Extracellular Traps (NETs) Take the Central Stage in Driving Autoimmune Responses (2020, Cells)
  • Abatacept in individuals at high risk of rheumatoid arthritis (APIPPRA): a randomised, double-blind, multicentre, parallel, placebo-controlled, phase 2b clinical trial (2024, The Lancet)
  • Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications (2020, Annals of the Rheumatic Diseases)
  • Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis (2020, Science Translational Medicine)
  • Onset of rheumatoid arthritis after COVID-19: coincidence or connected? (2021, Annals of the Rheumatic Diseases)

The scientist frequently collaborates with other researchers, including:

  • T. Huizinga
  • Hans Ulrich Scherer
  • Diane van der Woude
  • Theresa Kissel
  • Tineke J van Wesemael

Best Publications

  • T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

    S. P. Schoenberger;R. E. M. Toes;E. I. H. Van Der Voort;R. Offringa

  • Genetics of rheumatoid arthritis contributes to biology and drug discovery

    Yukinori Okada;Yukinori Okada;Di Wu;Di Wu;Di Wu;Gosia Trynka;Gosia Trynka;Towfique Raj;Towfique Raj

  • Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

    Eli A Stahl;Soumya Raychaudhuri;Soumya Raychaudhuri;Elaine F Remmers;Gang Xie

  • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses.

    R. P.M. Sutmuller;L. M. Van Duivenvoorde;A. Van Elsas;T. N.M. Schumacher

  • Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells.

    Jun Wang;Andreea Ioan-Facsinay;Ellen I. H. van der Voort;Tom W. J. Huizinga

  • Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis: a prospective cohort study.

    F.A. van Gaalen;S.P. Linn-Rasker;W.J.W. van Venrooij;B.A. de Jong

  • Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

    Ulrike Harre;Dan Georgess;Holger Bang;Aline Bozec

  • High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

    Steve Eyre;John Bowes;John Bowes;Dorothée Diogo;Dorothée Diogo;Annette Lee

  • Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins.

    Tom W. J. Huizinga;Christopher I. Amos;Annette H. M. van der Helm-van Mil;Wei Chen

  • Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

    B.J.E. de Lange-Brokaar;A. Ioan-Facsinay;G.J.V.M. van Osch;A.-M. Zuurmond

  • Decreased tumor surveillance in perforin-deficient mice.

    M. F. Van Den Broek;D. Kagi;F. Ossendorp;R. Toes

  • Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage

    Jing Shi;Rachel Knevel;Parawee Suwannalai;Michael P. van der Linden

  • Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis

    Annette H M van der Helm-van Mil;Kirsten N Verpoort;Ferdinand C Breedveld;René E M Toes

  • CD4 T cells and their role in antitumor immune responses.

    René E.M. Toes;Ferry Ossendorp;Rienk Offringa;Cornelis J.M. Melief

  • Common variants at CD40 and other loci confer risk of rheumatoid arthritis

    Soumya Raychaudhuri;Soumya Raychaudhuri;Soumya Raychaudhuri;Elaine F Remmers;Annette T Lee;Rachel Hackett

  • Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans.

    Mary E. Morgan;Jolanda H.M. van Bilsen;Aleida M. Bakker;Bianca Heemskerk

  • Gene-Gene and Gene-Environment Interactions Involving HLA-DRB1, PTPN22, and Smoking in Two Subsets of Rheumatoid Arthritis

    Henrik Källberg;Leonid Padyukov;Robert M. Plenge;Robert M. Plenge;Johan Rönnelid

  • CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy.

    Diehl L;den Boer At;Schoenberger Sp;van der Voort Ei

  • The heat shock protein gp96 induces maturation of dendritic cells and down-regulation of its receptor.

    Harpreet Singh-Jasuja;Hans Ulrich Scherer;Norbert Hilf;Danièle Arnold-Schild

  • Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: A double‐blind, randomized, placebo‐controlled trial

    Henrike van Dongen;Jill van Aken;Leroy R Lard;Karen Visser

  • Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid Arthritis

    Floris A van Gaalen;Jill van Aken;Tom W J Huizinga;Geziena M Th Schreuder

Frequent Co-Authors

Tom W. J. Huizinga
Tom W. J. Huizinga Leiden University Medical Center
Leendert A. Trouw
Leendert A. Trouw Leiden University Medical Center
Rienk Offringa
Rienk Offringa German Cancer Research Center
Cornelis J. M. Melief
Cornelis J. M. Melief ISA Pharmaceuticals (Netherlands)
Jeanine J. Houwing-Duistermaat
Jeanine J. Houwing-Duistermaat University of Leeds
Lars Klareskog
Lars Klareskog Karolinska Institute
Alexandra Zhernakova
Alexandra Zhernakova University Medical Center Groningen
Peter K. Gregersen
Peter K. Gregersen Feinstein Institute for Medical Research
Soumya Raychaudhuri
Soumya Raychaudhuri Brigham and Women's Hospital
Robert M. Plenge
Robert M. Plenge Bristol Myers Squibb

External Links

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Best Scientists Citing René E. M. Toes

Lars Klareskog

Lars Klareskog

Karolinska Institute

Publications: 172

Anne Barton

Anne Barton

University of Manchester

Publications: 125

Soumya Raychaudhuri

Soumya Raychaudhuri

Brigham and Women's Hospital

Publications: 122

Leonid Padyukov

Leonid Padyukov

Karolinska Institute

Publications: 109

Tom W. J. Huizinga

Tom W. J. Huizinga

Leiden University Medical Center

Publications: 107

Lars Alfredsson

Lars Alfredsson

Karolinska Institute

Publications: 105

Rikard Holmdahl

Rikard Holmdahl

Karolinska Institute

Publications: 100

Paul Emery

Paul Emery

University of Leeds

Publications: 97

Cornelis J. M. Melief

Cornelis J. M. Melief

ISA Pharmaceuticals (Netherlands)

Publications: 97

Jane Worthington

Jane Worthington

University of Manchester

Publications: 96

Peter K. Gregersen

Peter K. Gregersen

Feinstein Institute for Medical Research

Publications: 95

Yukinori Okada

Yukinori Okada

Osaka University

Publications: 91

Paul P. Tak

Paul P. Tak

GlaxoSmithKline (United Kingdom)

Publications: 90

Robert M. Plenge

Robert M. Plenge

Bristol Myers Squibb

Publications: 86

John D. Isaacs

John D. Isaacs

Newcastle University

Publications: 84

Kazuhiko Yamamoto

Kazuhiko Yamamoto

RIKEN

Publications: 83

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