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Biology and Biochemistry

D-Index
77
Citations
24337
World Ranking
4728
National Ranking
2290

Overview

John Moult is affiliated with the University of Maryland, College Park in the United States. Their research focuses on fields related to Biochemistry, Genetics, and Molecular Biology, with a particular emphasis on Molecular Biology. They have also contributed to areas including Materials Chemistry, Computational Theory and Mathematics, Genetics, and Cancer Research.

The scientist's research covers key topics such as:

  • RNA and protein synthesis mechanisms
  • Protein Structure and Dynamics
  • Enzyme Structure and Function
  • RNA modifications and cancer
  • Computational Drug Discovery Methods
  • Genomics and Rare Diseases
  • Biomedical Text Mining and Ontologies

John Moult has authored numerous papers, including significant contributions to the Critical Assessment of Structure Prediction (CASP) series. Notable recent publications include:

  • Critical assessment of methods of protein structure prediction (CASP) - Round XIV, 2021, Proteins Structure Function and Bioinformatics
  • Critical assessment of methods of protein structure prediction (CASP) - Round XV, 2023, Proteins Structure Function and Bioinformatics
  • CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding, 2022, Nature Reviews Chemistry
  • New prediction categories in CASP15, 2023, Proteins Structure Function and Bioinformatics
  • CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods, 2024, Genome biology

Frequent co-authors in their research output include:

  • Andriy Kryshtafovych
  • Krzysztof Fidelis
  • Torsten Schwede
  • Maya Topf
  • M.D. Hartmann

John Moult's work is regularly published in journals such as:

  • Proteins Structure Function and Bioinformatics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Reviews Chemistry
  • Genome biology

Best Publications

  • SNPs, protein structure, and disease

    Zhen Wang;John Moult

  • Genetic algorithms for protein folding simulations

    Ron Unger;John Moult

  • CAPRI: A Critical Assessment of PRedicted Interactions

    Joel Janin;Kim Henrick;John Moult;Lynn Ten Eyck

  • Critical assessment of methods of protein structure prediction (CASP) — round x

    John Moult;Krzysztof Fidelis;Andriy Kryshtafovych;Torsten Schwede

  • A large-scale experiment to assess protein structure prediction methods.

    John Moult;Jan T. Pedersen;Richard Judson;Krzysztof Fidelis

  • A decade of CASP: progress, bottlenecks and prognosis in protein structure prediction.

    John Moult

  • The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H through genomic and proteomic analyses

    Barbara A. Methé;Karen E. Nelson;Jody W. Deming;Bahram Momen

  • An all-atom distance-dependent conditional probability discriminatory function for protein structure prediction.

    Ram Samudrala;John Moult

  • Critical assessment of methods of protein structure prediction (CASP)-Round XIII

    Andriy Kryshtafovych;Torsten Schwede;Maya Topf;Krzysztof Fidelis

  • SNPs3D: Candidate gene and SNP selection for association studies

    Peng-Fei Yue;Peng-Fei Yue;Eugene Melamud;Eugene Melamud;John Moult

  • Loss of protein structure stability as a major causative factor in monogenic disease.

    Peng Yue;Zhaolong Li;John Moult

  • Critical assessment of methods of protein structure prediction (CASP)-Round XIV.

    Andriy Kryshtafovych;Torsten Schwede;Maya Topf;Krzysztof Fidelis

  • Completeness in structural genomics.

    Dennis Vitkup;Dennis Vitkup;Eugene Melamud;John Moult;Chris Sander;Chris Sander

  • Bacterial resistance to beta-lactam antibiotics: crystal structure of beta-lactamase from Staphylococcus aureus PC1 at 2.5 A resolution.

    Osnat Herzberg;John Moult

  • Critical assessment of methods of protein structure prediction (CASP): round III.

    John Moult;Tim Hubbard;Krzysztof Fidelis;Jan T. Pedersen

  • Critical assessment of methods of protein structure prediction (CASP)-Round XII

    John Moult;Krzysztof Fidelis;Andriy Kryshtafovych;Torsten Schwede

  • A model for the Ca2+-induced conformational transition of troponin C. A trigger for muscle contraction.

    O Herzberg;J Moult;M N James

  • An algorithm for determining the conformation of polypeptide segments in proteins by systematic search.

    J. Moult;M. N. G. James

  • Critical assessment of methods of protein structure prediction (CASP): Round II

    John Moult;Tim Hubbard;Stephen H. Bryant;Krzysztof Fidelis

  • Critical assessment of methods of protein structure prediction (CASP)- Round IX

    John Moult;Krzysztof Fidelis;Andriy Kryshtafovych;Anna Tramontano

Frequent Co-Authors

Andriy Kryshtafovych
Andriy Kryshtafovych University of California, Davis
Osnat Herzberg
Osnat Herzberg University of Maryland, College Park
Torsten Schwede
Torsten Schwede University of Basel
Steven E. Brenner
Steven E. Brenner University of California, Berkeley
Anna Tramontano
Anna Tramontano Sapienza University of Rome
Predrag Radivojac
Predrag Radivojac Northeastern University
Silvio C. E. Tosatto
Silvio C. E. Tosatto University of Padua
Andrzej Joachimiak
Andrzej Joachimiak Argonne National Laboratory
Olivier Lichtarge
Olivier Lichtarge Baylor College of Medicine
Rita Casadio
Rita Casadio University of Bologna

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