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Genetics

D-Index
86
Citations
65436
World Ranking
1228
National Ranking
583

Overview

Steven E. Brenner is affiliated with the University of California, Berkeley in the United States. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with a significant number of publications in related subfields such as molecular biology, genetics, cancer research, clinical biochemistry, and plant science.

Their work covers several main topics, including:

  • Genomics and rare diseases
  • Genomic variations and chromosomal abnormalities
  • RNA and protein synthesis mechanisms
  • Cancer genomics and diagnostics
  • RNA modifications and cancer
  • Genetic associations and epidemiology
  • Metabolism and genetic disorders

Steven E. Brenner has published extensively, contributing numerous papers in reputable venues. Frequent publication outlets include bioRxiv (Cold Spring Harbor Laboratory), Human Genetics, The American Journal of Human Genetics, Zenodo (CERN European Organization for Nuclear Research), and npj Genomic Medicine.

Among the recent papers authored or coauthored:

  • "Calibration of computational tools for missense variant pathogenicity classification and ClinGen recommendations for PP3/BP4 criteria," 2022, The American Journal of Human Genetics
  • "Using the ACMG/AMP framework to capture evidence related to predicted and observed impact on splicing: Recommendations from the ClinGen SVI Splicing Subgroup," 2023, The American Journal of Human Genetics
  • "The role of exome sequencing in newborn screening for inborn errors of metabolism," 2020, Nature Medicine
  • "SCOPe: improvements to the structural classification of proteins - extended database to facilitate variant interpretation and machine learning," 2021, Nucleic Acids Research
  • "Opportunities and challenges for the computational interpretation of rare variation in clinically important genes," 2021, The American Journal of Human Genetics

The scientist collaborates frequently with several coauthors, including:

  • Predrag Radivojac
  • Vikas Pejaver
  • Constantina Bakolitsa
  • Andrew G. Sharo
  • Zhiqiang Hu

Best Publications

  • WebLogo: A Sequence Logo Generator

    Gavin E. Crooks;Gary Hon;John Marc Chandonia;Steven E. Brenner;Steven E. Brenner

  • SCOP: a structural classification of proteins database for the investigation of sequences and structures.

    Alexey G. Murzin;Steven E. Brenner;Tim Hubbard;Cyrus Chothia

  • The Transcriptional Landscape of the Mammalian Genome

    P. Carninci;T. Kasukawa;S. Katayama;J. Gough

  • The Bioperl Toolkit: Perl Modules for the Life Sciences

    Jason E. Stajich;David Block;David Block;Kris Boulez;Steven E. Brenner

  • The developmental transcriptome of Drosophila melanogaster

    Brenton R. Graveley;Angela N. Brooks;Joseph W. Carlson;Michael O. Duff

  • KBase: The United States Department of Energy Systems Biology Knowledgebase.

    Adam P. Arkin;Adam P. Arkin;Robert W. Cottingham;Christopher S. Henry;Nomi L. Harris

  • Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

    Benjamin P. Lewis;Richard E. Green;Steven E. Brenner

  • Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

    Sushmita Roy;Jason Ernst;Peter V. Kharchenko;Pouya Kheradpour

  • SCOP Database in 2004: Refinements Integrate Structure and Sequence Family Data

    Antonina Andreeva;Dave Howorth;Steven E. Brenner;Tim J. P. Hubbard

  • A large-scale evaluation of computational protein function prediction

    Predrag Radivojac;Wyatt T Clark;Tal Ronnen Oron;Alexandra M Schnoes

  • Data growth and its impact on the SCOP database: new developments.

    Antonina Andreeva;Dave Howorth;John-Marc Chandonia;Steven E. Brenner

  • Errors in genome annotation.

    Steven E. Brenner

  • The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families.

    Shibu Yooseph;Granger Sutton;Douglas B. Rusch;Aaron L Halpern

  • SCOP: a Structural Classification of Proteins database

    Tim J. P. Hubbard;Bart Ailey;Steven E. Brenner;Alexey G. Murzin

  • Biases in Illumina transcriptome sequencing caused by random hexamer priming

    Kasper D. Hansen;Steven E. Brenner;Sandrine Dudoit

  • SCOPe: Structural Classification of Proteins—extended, integrating SCOP and ASTRAL data and classification of new structures

    Naomi K. Fox;Steven E. Brenner;John-Marc Chandonia

  • Characterization of the pufferfish ( Fugu ) genome as a compact model vertebrate genome

    Brenner S;Elgar G;Sandford R;Macrae A

  • The ASTRAL Compendium in 2004.

    John-Marc Chandonia;Gary Chung Hon;Nigel S. Walker;Loredana Lo Conte

  • Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements

    Liana F Lareau;Maki Inada;Richard E Green;Jordan C Wengrod

  • Assessing sequence comparison methods with reliable structurally identified distant evolutionary relationships

    Steven E. Brenner;Cyrus Chothia;Tim J. P. Hubbard

Frequent Co-Authors

Tim Hubbard
Tim Hubbard King's College London
Richard E. Green
Richard E. Green University of California, Santa Cruz
Sean D. Mooney
Sean D. Mooney University of Washington
Predrag Radivojac
Predrag Radivojac Northeastern University
Rita Casadio
Rita Casadio University of Bologna
John Moult
John Moult University of Maryland, College Park
Cyrus Chothia
Cyrus Chothia MRC Laboratory of Molecular Biology
Silvio C. E. Tosatto
Silvio C. E. Tosatto University of Padua
Jennifer M. Puck
Jennifer M. Puck University of California, San Francisco
Olivier Lichtarge
Olivier Lichtarge Baylor College of Medicine

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