D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 51 Citations 13,041 239 World Ranking 9559 National Ranking 4207

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • DNA

The scientist’s investigation covers issues in Biochemistry, Thermotoga maritima, Protein structure, Structural genomics and Crystallography. Scott A. Lesley regularly links together related areas like Stereochemistry in his Biochemistry studies. His research in Thermotoga maritima intersects with topics in Proteome, Resolution, Aquatic organisms and Protein folding.

His studies in Structural genomics integrate themes in fields like Structural biology, Computational biology and Protein Structure Initiative, Genomics. His Computational biology research is multidisciplinary, incorporating elements of Genetics, Protein expression, Proteomics, Primer extension and Cloning. His Crystallography study combines topics in areas such as Crystallization and Protein crystallization.

His most cited work include:

  • Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites (1477 citations)
  • Protein production and purification. (655 citations)
  • Protein production and purification. (655 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Biochemistry, Thermotoga maritima, Structural genomics, Peptide sequence and Crystal structure. Biochemistry is represented through his Protein structure, Active site, Hydrolase, Plasma protein binding and Enzyme research. As part of one scientific family, he deals mainly with the area of Thermotoga maritima, narrowing it down to issues related to the Crystallography, and often Crystallization.

Scott A. Lesley has included themes like Genetics, Protein folding, Protein family, Computational biology and Protein Structure Initiative in his Structural genomics study. The Peptide sequence study combines topics in areas such as Structural similarity, Bacteroides thetaiotaomicron and Binding site. His Crystal structure research integrates issues from Resolution and Stereochemistry.

He most often published in these fields:

  • Biochemistry (80.54%)
  • Thermotoga maritima (41.62%)
  • Structural genomics (47.01%)

What were the highlights of his more recent work (between 2011-2020)?

  • Biochemistry (80.54%)
  • Active site (24.85%)
  • Stereochemistry (29.04%)

In recent papers he was focusing on the following fields of study:

Scott A. Lesley spends much of his time researching Biochemistry, Active site, Stereochemistry, Protein structure and Structural genomics. His Biochemistry study is mostly concerned with Hydrolase, Plasma protein binding, Peptide sequence, Sequence alignment and Peptidoglycan. His work carried out in the field of Peptide sequence brings together such families of science as Isomerase, Computational biology and Cytidine monophosphate.

Scott A. Lesley works mostly in the field of Stereochemistry, limiting it down to topics relating to Cofactor binding and, in certain cases, Protein Data Bank, Flavin mononucleotide and Crystallography, as a part of the same area of interest. He works mostly in the field of Protein structure, limiting it down to topics relating to Crystal structure and, in certain cases, Protein subunit, Gating and Transporter. His Structural genomics research includes themes of Clostripain, C-terminus, Cysteine protease and Protein family.

Between 2011 and 2020, his most popular works were:

  • Co-regulatory networks of human serum proteins link genetics to disease (140 citations)
  • Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice (97 citations)
  • A Distinct Type of Pilus from the Human Microbiome. (40 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

Scott A. Lesley mostly deals with Biochemistry, Stereochemistry, Hydrolase, Active site and Cell biology. His work in Biochemistry is not limited to one particular discipline; it also encompasses Antibody. The concepts of his Stereochemistry study are interwoven with issues in Cofactor binding, Cofactor, Flavin group, Enzyme and CYP8B1.

His work carried out in the field of Hydrolase brings together such families of science as Peptidoglycan, Peptidoglycan binding and Amidase. The study incorporates disciplines such as Peptide sequence, Sequence alignment, Cell wall and Lysozyme in addition to Active site. His studies in Thermotoga maritima integrate themes in fields like Binding protein and Plasma protein binding.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

William R. Wikoff;Andrew T. Anfora;Jun Liu;Peter G. Schultz.
Proceedings of the National Academy of Sciences of the United States of America (2009)

1903 Citations

Protein production and purification.

S Gräslund.
Nature Methods (2008)

842 Citations

Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline

Scott A. Lesley;Peter Kuhn;Adam Godzik;Ashley M. Deacon.
Proceedings of the National Academy of Sciences of the United States of America (2002)

505 Citations

Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts

Heath E. Klock;Eric J. Koesema;Mark W. Knuth;Scott A. Lesley.
Proteins (2008)

374 Citations

High throughput processing system and method of using

Kristina Marie Burow;Jeremy S. Caldwell;Robert Charles Downs;Scott Allan Lesley.
(2001)

351 Citations

The Polymerase Incomplete Primer Extension (PIPE) Method Applied to High-Throughput Cloning and Site-Directed Mutagenesis

Heath E. Klock;Scott A. Lesley.
Methods of Molecular Biology (2009)

311 Citations

XtalPred: a web server for prediction of protein crystallizability.

Lukasz Slabinski;Lukasz Jaroszewski;Leszek Rychlewski;Ian A. Wilson.
Bioinformatics (2007)

291 Citations

Size and Shape of Detergent Micelles Determined by Small-Angle X-ray Scattering

Jan Lipfert;Linda Columbus;Vincent B. Chu;Scott A. Lesley.
Journal of Physical Chemistry B (2007)

244 Citations

Use of in vitro protein synthesis from polymerase chain reaction-generated templates to study interaction of Escherichia coli transcription factors with core RNA polymerase and for epitope mapping of monoclonal antibodies.

S. A. Lesley;M. A. D. Brow;R. R. Burgess.
Journal of Biological Chemistry (1991)

243 Citations

High-throughput proteomics: protein expression and purification in the postgenomic world.

Scott A. Lesley.
Protein Expression and Purification (2001)

231 Citations

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