The scientist’s investigation covers issues in Biochemistry, Thermotoga maritima, Protein structure, Structural genomics and Crystallography. Scott A. Lesley regularly links together related areas like Stereochemistry in his Biochemistry studies. His research in Thermotoga maritima intersects with topics in Proteome, Resolution, Aquatic organisms and Protein folding.
His studies in Structural genomics integrate themes in fields like Structural biology, Computational biology and Protein Structure Initiative, Genomics. His Computational biology research is multidisciplinary, incorporating elements of Genetics, Protein expression, Proteomics, Primer extension and Cloning. His Crystallography study combines topics in areas such as Crystallization and Protein crystallization.
His main research concerns Biochemistry, Thermotoga maritima, Structural genomics, Peptide sequence and Crystal structure. Biochemistry is represented through his Protein structure, Active site, Hydrolase, Plasma protein binding and Enzyme research. As part of one scientific family, he deals mainly with the area of Thermotoga maritima, narrowing it down to issues related to the Crystallography, and often Crystallization.
Scott A. Lesley has included themes like Genetics, Protein folding, Protein family, Computational biology and Protein Structure Initiative in his Structural genomics study. The Peptide sequence study combines topics in areas such as Structural similarity, Bacteroides thetaiotaomicron and Binding site. His Crystal structure research integrates issues from Resolution and Stereochemistry.
Scott A. Lesley spends much of his time researching Biochemistry, Active site, Stereochemistry, Protein structure and Structural genomics. His Biochemistry study is mostly concerned with Hydrolase, Plasma protein binding, Peptide sequence, Sequence alignment and Peptidoglycan. His work carried out in the field of Peptide sequence brings together such families of science as Isomerase, Computational biology and Cytidine monophosphate.
Scott A. Lesley works mostly in the field of Stereochemistry, limiting it down to topics relating to Cofactor binding and, in certain cases, Protein Data Bank, Flavin mononucleotide and Crystallography, as a part of the same area of interest. He works mostly in the field of Protein structure, limiting it down to topics relating to Crystal structure and, in certain cases, Protein subunit, Gating and Transporter. His Structural genomics research includes themes of Clostripain, C-terminus, Cysteine protease and Protein family.
Scott A. Lesley mostly deals with Biochemistry, Stereochemistry, Hydrolase, Active site and Cell biology. His work in Biochemistry is not limited to one particular discipline; it also encompasses Antibody. The concepts of his Stereochemistry study are interwoven with issues in Cofactor binding, Cofactor, Flavin group, Enzyme and CYP8B1.
His work carried out in the field of Hydrolase brings together such families of science as Peptidoglycan, Peptidoglycan binding and Amidase. The study incorporates disciplines such as Peptide sequence, Sequence alignment, Cell wall and Lysozyme in addition to Active site. His studies in Thermotoga maritima integrate themes in fields like Binding protein and Plasma protein binding.
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Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
William R. Wikoff;Andrew T. Anfora;Jun Liu;Peter G. Schultz.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Protein production and purification.
Nature Methods (2008)
Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline
Scott A. Lesley;Peter Kuhn;Adam Godzik;Ashley M. Deacon.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts
Heath E. Klock;Eric J. Koesema;Mark W. Knuth;Scott A. Lesley.
High throughput processing system and method of using
Kristina Marie Burow;Jeremy S. Caldwell;Robert Charles Downs;Scott Allan Lesley.
The Polymerase Incomplete Primer Extension (PIPE) Method Applied to High-Throughput Cloning and Site-Directed Mutagenesis
Heath E. Klock;Scott A. Lesley.
Methods of Molecular Biology (2009)
XtalPred: a web server for prediction of protein crystallizability.
Lukasz Slabinski;Lukasz Jaroszewski;Leszek Rychlewski;Ian A. Wilson.
Size and Shape of Detergent Micelles Determined by Small-Angle X-ray Scattering
Jan Lipfert;Linda Columbus;Vincent B. Chu;Scott A. Lesley.
Journal of Physical Chemistry B (2007)
Use of in vitro protein synthesis from polymerase chain reaction-generated templates to study interaction of Escherichia coli transcription factors with core RNA polymerase and for epitope mapping of monoclonal antibodies.
S. A. Lesley;M. A. D. Brow;R. R. Burgess.
Journal of Biological Chemistry (1991)
High-throughput proteomics: protein expression and purification in the postgenomic world.
Scott A. Lesley.
Protein Expression and Purification (2001)
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